Effects of COVID-19 hospitalization rates on the incidence of hospital-acquired Candida central line-associated bloodstream infection.
Candida bloodstream infection
Central line bloodstream infection
Health care–associated Infections
Journal
American journal of infection control
ISSN: 1527-3296
Titre abrégé: Am J Infect Control
Pays: United States
ID NLM: 8004854
Informations de publication
Date de publication:
Apr 2024
Apr 2024
Historique:
received:
24
08
2023
revised:
03
10
2023
accepted:
04
10
2023
pubmed:
10
10
2023
medline:
10
10
2023
entrez:
9
10
2023
Statut:
ppublish
Résumé
An increase in central line-associated bloodstream infections (CLABSIs) has been reported during the Coronavirus (COVID-19) pandemic; however, few studies have documented causative pathogens, particularly Candida species associated with candidemia. This was a retrospective study based on the National Health Care Safety Network surveillance definitions of CLABSI caused by Candida species during pre-COVID-19 (October 2017 to February 2020) and COVID-19 (March 2020 to December 2021) periods within a local community hospital. Candida CLABSI incidence per 1,000 central line days was compared between periods using the χ Overall CLABSI (0.68 vs 1.98 per 1,000, P = .004) and Candida CLABSI incidence (0.06 vs 0.77 per 1,000, P = .003) significantly increased from pre-COVID-19 to COVID-19 periods. There was a significant correlation between COVID-19 ICU hospitalizations and CLABSIs (R = 0.18, P = .048), but not acute care hospitalizations and CLABSIs (R = 0.065, P = .250). Conversely, there was a significant association between COVID-19 acute care hospitalizations and Candida CLABSIs (R = 0.50, P < .001), but not COVID-19 ICU hospitalizations and Candida CLABSIs (R = 0.01, P = .631). During the COVID-19 pandemic, our facility experienced a significant increase in Candida CLABSI and a significant correlation of Candida CLABSIs with acute care COVID-19 hospitalizations.
Sections du résumé
BACKGROUND
BACKGROUND
An increase in central line-associated bloodstream infections (CLABSIs) has been reported during the Coronavirus (COVID-19) pandemic; however, few studies have documented causative pathogens, particularly Candida species associated with candidemia.
METHODS
METHODS
This was a retrospective study based on the National Health Care Safety Network surveillance definitions of CLABSI caused by Candida species during pre-COVID-19 (October 2017 to February 2020) and COVID-19 (March 2020 to December 2021) periods within a local community hospital. Candida CLABSI incidence per 1,000 central line days was compared between periods using the χ
RESULTS
RESULTS
Overall CLABSI (0.68 vs 1.98 per 1,000, P = .004) and Candida CLABSI incidence (0.06 vs 0.77 per 1,000, P = .003) significantly increased from pre-COVID-19 to COVID-19 periods. There was a significant correlation between COVID-19 ICU hospitalizations and CLABSIs (R = 0.18, P = .048), but not acute care hospitalizations and CLABSIs (R = 0.065, P = .250). Conversely, there was a significant association between COVID-19 acute care hospitalizations and Candida CLABSIs (R = 0.50, P < .001), but not COVID-19 ICU hospitalizations and Candida CLABSIs (R = 0.01, P = .631).
CONCLUSIONS
CONCLUSIONS
During the COVID-19 pandemic, our facility experienced a significant increase in Candida CLABSI and a significant correlation of Candida CLABSIs with acute care COVID-19 hospitalizations.
Identifiants
pubmed: 37813280
pii: S0196-6553(23)00677-6
doi: 10.1016/j.ajic.2023.10.002
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
387-391Informations de copyright
Published by Elsevier Inc.