A repository of grade 1 and 2 meningioma MRIs in a public dataset for radiomics reproducibility tests.

TCIA atypical dataset meningioma radiomics

Journal

Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746

Informations de publication

Date de publication:
10 Oct 2023
Historique:
revised: 24 07 2023
received: 23 05 2023
accepted: 28 08 2023
medline: 10 10 2023
pubmed: 10 10 2023
entrez: 10 10 2023
Statut: aheadofprint

Résumé

Meningiomas are the most common primary brain tumors in adults with management varying widely based on World Health Organization (WHO) grade. However, there are limited datasets available for researchers to develop and validate radiomic models. The purpose of our manuscript is to report on the first dataset of meningiomas in The Cancer Imaging Archive (TCIA). The dataset consists of pre-operative MRIs from 96 patients with meningiomas who underwent resection from 2010-2019 and include axial T1post and T2-FLAIR sequences-55 grade 1 and 41 grade 2. Meningioma grade was confirmed based on the 2016 WHO Bluebook classification guideline by two neuropathologists and one neuropathology fellow. The hyperintense T1post tumor and hyperintense T2-FLAIR regions were manually contoured on both sequences and resampled to an isotropic resolution of 1 × 1 × 1 mm The data was imported into TCIA for storage and can be accessed at https://doi.org/10.7937/0TKV-1A36. The total size of the dataset is 8.8GB, with 47 519 individual Digital Imaging and Communications in Medicine (DICOM) files consisting of 384 image series, and 192 structures. Grade 1 and 2 meningiomas have different treatment paradigms and are often treated based on radiologic diagnosis alone. Therefore, predicting grade prior to treatment is essential in clinical decision-making. This dataset will allow researchers to create models to auto-differentiate grade 1 and 2 meningiomas as well as evaluate for other pathologic features including mitotic index, brain invasion, and atypical features. Limitations of this study are the small sample size and inclusion of only two MRI sequences. However, there are no meningioma datasets on TCIA and limited datasets elsewhere although meningiomas are the most common intracranial tumor in adults.

Identifiants

pubmed: 37815256
doi: 10.1002/mp.16763
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023 American Association of Physicists in Medicine.

Références

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Auteurs

April Vassantachart (A)

Department of Radiation Oncology, LAC+USC Medical Center, Los Angeles, California, USA.
Department of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Yufeng Cao (Y)

Department of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Zhilei Shen (Z)

Department of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Karen Cheng (K)

Department of Radiation Oncology, LAC+USC Medical Center, Los Angeles, California, USA.
Department of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Michael Gribble (M)

Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Jason C Ye (JC)

Department of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Gabriel Zada (G)

Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Kyle Hurth (K)

Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Anna Mathew (A)

Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Samuel Guzman (S)

Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Wensha Yang (W)

Department of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Classifications MeSH