Different methods for resolving overlapping UV spectra of combination medicinal dose forms of ciprofloxacin and metronidazole.
Advanced absorbance subtraction (AAS)
Bivariate
Ciprofloxacin
Metronidazole
Ratio difference
Spectrum subtraction
Journal
BMC chemistry
ISSN: 2661-801X
Titre abrégé: BMC Chem
Pays: Switzerland
ID NLM: 101741142
Informations de publication
Date de publication:
10 Oct 2023
10 Oct 2023
Historique:
received:
12
04
2023
accepted:
17
07
2023
medline:
11
10
2023
pubmed:
11
10
2023
entrez:
11
10
2023
Statut:
epublish
Résumé
Four simple, specific, easy, precise and accurate spectrophotometric methods were developed for the first time to examine ciprofloxacin and metronidazole in combination, without having been separated beforehand by the developed methods. Ciprofloxacin and metronidazole were determined by utilizing advanced absorbance subtraction (AAS), spectrum subtraction, bivariate and ratio difference methods. Precision, repeatability, robustness, and accuracy were all determined to be within acceptable levels after each of these procedures underwent validation in accordance with ICH recommendations. Each method's benefits and drawbacks are illustrated, and the proposed and reported methodologies were statistically compared.
Identifiants
pubmed: 37817284
doi: 10.1186/s13065-023-01007-z
pii: 10.1186/s13065-023-01007-z
pmc: PMC10566196
doi:
Types de publication
Journal Article
Langues
eng
Pagination
137Informations de copyright
© 2023. Springer Nature Switzerland AG.
Références
Talanta. 2000 Aug 16;52(5):845-52
pubmed: 18968044
Spectrochim Acta A Mol Biomol Spectrosc. 2020 Jan 5;224:117429
pubmed: 31394394
J Pharm Biomed Anal. 2005 Apr 29;37(5):851-8
pubmed: 15862658
J Enzyme Inhib Med Chem. 2010 Aug;25(4):577-89
pubmed: 20235755
J Adv Nurs. 1996 Aug;24(2):244-50
pubmed: 8858426
BMJ Open. 2018 Jan 23;8(1):e015332
pubmed: 29362241
Value Health. 2008 Jan-Feb;11(1):44-7
pubmed: 18237359
Spectrochim Acta A Mol Biomol Spectrosc. 2013 Oct;114:592-8
pubmed: 23807049
Clin Ther. 2004 Oct;26(10):1564-77
pubmed: 15598473
J Chromatogr B Analyt Technol Biomed Life Sci. 2015 May 1;989:80-5
pubmed: 25813900
J Anal Methods Chem. 2019 Sep 8;2019:8919345
pubmed: 31612094
J Pharm Biomed Anal. 1999 Dec;21(5):1003-9
pubmed: 10703968
Spectrochim Acta A Mol Biomol Spectrosc. 2018 Dec 5;205:160-169
pubmed: 30015021
Spectrochim Acta A Mol Biomol Spectrosc. 2016 Feb 5;154:232-236
pubmed: 26540201
Chem Pharm Bull (Tokyo). 2011;59(12):1485-93
pubmed: 22130371
Spectrochim Acta A Mol Biomol Spectrosc. 2022 Feb 5;266:120436
pubmed: 34619509
Spectrochim Acta A Mol Biomol Spectrosc. 2022 Apr 5;270:120819
pubmed: 35033809
J Pharm Biomed Anal. 2003 Sep 15;33(1):125-30
pubmed: 12946539
Spectrochim Acta A Mol Biomol Spectrosc. 2015 Sep 5;148:328-37
pubmed: 25909908
Ann Pharm Fr. 2021 Jan;79(1):3-15
pubmed: 32777297