Vaginal atrophy and genital pain in women on depot medroxyprogesterone acetate contraceptive injection.

atrophy dyspareunia medroxyprogesterone acetate sexual dysfunction vaginal diseases

Journal

The Australian & New Zealand journal of obstetrics & gynaecology
ISSN: 1479-828X
Titre abrégé: Aust N Z J Obstet Gynaecol
Pays: Australia
ID NLM: 0001027

Informations de publication

Date de publication:
10 Oct 2023
Historique:
received: 20 06 2023
accepted: 25 09 2023
medline: 11 10 2023
pubmed: 11 10 2023
entrez: 11 10 2023
Statut: aheadofprint

Résumé

Depot medroxyprogesterone acetate causes a hypo-estrogenic state in over half of users although clinical vaginal atrophy causing superficial dyspareunia is thought rarely to occur. This is a case series of ten women using depot medroxyprogesterone acetate who presented with superficial dyspareunia and clinical vaginal atrophy. The women were treated with vaginal estriol cream and their contraception was discontinued or changed. All patients had either a complete resolution of symptoms or a substantial improvement at follow-up, and the clinical and laboratory findings of vaginal atrophy had resolved. This case series demonstrates that vaginal atrophy may occur more frequently than previously thought.

Identifiants

pubmed: 37817446
doi: 10.1111/ajo.13757
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023 Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

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Auteurs

Nicky Perkins (N)

Auckland Sexual Health Service, Te Whatu Ora/Te Toka Tumai, Auckland, New Zealand.

Classifications MeSH