Orthodontic appliances for the treatment of pediatric obstructive sleep apnea: A systematic review and network meta-analysis.


Journal

Sleep medicine reviews
ISSN: 1532-2955
Titre abrégé: Sleep Med Rev
Pays: England
ID NLM: 9804678

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 07 08 2023
revised: 12 09 2023
accepted: 19 09 2023
medline: 27 11 2023
pubmed: 12 10 2023
entrez: 11 10 2023
Statut: ppublish

Résumé

This systematic review and network meta-analysis aims to preliminarily investigate the efficacy of different orthodontic appliances for the treatment of pediatric obstructive sleep apnea (OSA). Electronic databases were systematically searched. Randomized and non-randomized controlled trials with patients <18 y treated with either mandibular advancement appliance (MAA), rapid maxillary expansion (RME), or myofunctional therapy (MFT) were included. A network meta-analysis using multivariate random effects was conducted to estimate pooled differences using the apnea-hypopnea index (AHI) as the main outcome. Eleven studies (595 patients) were included in the analysis. Compared with control, MAA was associated with significant reductions in AHI of -2.18/h (95%CI -3.48 to -0.89, p = 0.001). Combined treatment of RME + adenotonsillectomy (AT) and RME + MAA showed a significant decrease in AHI, with -5.13/h (95%CI -7.50 to -2.76, p < 0.0001) and -3.79 (95%CI -5.21 to -2.37, p < 0.0001), respectively. MFT was associated with a -2.45/h (95%CI -4.76 to -0.14, p = 0.038) decrease in AHI. However, RME alone was not associated with significant AHI reduction (0.02, 95%CI -1.72 to 1.75, p = 0.985). The heterogeneity of the network meta-analysis was I

Identifiants

pubmed: 37820534
pii: S1087-0792(23)00111-9
doi: 10.1016/j.smrv.2023.101855
pii:
doi:

Types de publication

Meta-Analysis Systematic Review Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

101855

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Min Yu (M)

Department of Orthodontics, Peking University School and Hospital of Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China; Center for Oral Therapy of Sleep Apnea, Peking University Hospital of Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China; National Center for Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China.

Yanyan Ma (Y)

Department of Stomatology, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, PR China.

Ying Xu (Y)

Department of Orthodontics, Peking University School and Hospital of Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China; Center for Oral Therapy of Sleep Apnea, Peking University Hospital of Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China; National Center for Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China.

Jingxuan Bai (J)

Department of Orthodontics, Peking University School and Hospital of Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China; Center for Oral Therapy of Sleep Apnea, Peking University Hospital of Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China; National Center for Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China.

Yujia Lu (Y)

Department of Orthodontics, Peking University School and Hospital of Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China; Center for Oral Therapy of Sleep Apnea, Peking University Hospital of Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China; National Center for Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China.

Fang Han (F)

Sleep Division, Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, 100044, PR China. Electronic address: hanfang1@hotmail.com.

Xuemei Gao (X)

Department of Orthodontics, Peking University School and Hospital of Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China; Center for Oral Therapy of Sleep Apnea, Peking University Hospital of Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China; National Center for Stomatology, No. 22 Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China. Electronic address: xmgao@263.net.

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