KMT2D suppresses Sonic hedgehog-driven medulloblastoma progression and metastasis.
Cancer
Genetics
Model organism
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
20 Oct 2023
20 Oct 2023
Historique:
received:
24
08
2022
revised:
29
03
2023
accepted:
01
09
2023
medline:
12
10
2023
pubmed:
12
10
2023
entrez:
12
10
2023
Statut:
epublish
Résumé
The major cause of treatment failure and mortality among medulloblastoma patients is metastasis intracranially or along the spinal cord. The molecular mechanisms driving tumor metastasis in Sonic hedgehog-driven medulloblastoma (SHH-MB) patients, however, remain largely unknown. In this study we define a tumor suppressive role of
Identifiants
pubmed: 37822508
doi: 10.1016/j.isci.2023.107831
pii: S2589-0042(23)01908-9
pmc: PMC10562805
doi:
Types de publication
Journal Article
Langues
eng
Pagination
107831Informations de copyright
© 2023 The Authors.
Déclaration de conflit d'intérêts
The authors declare no competing interests.
Références
J Korean Neurosurg Soc. 2018 May;61(3):292-301
pubmed: 29742881
Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3392-3397
pubmed: 29531057
Nature. 2019 Aug;572(7767):67-73
pubmed: 31043743
Elife. 2019 Apr 16;8:
pubmed: 30990415
Cell. 2018 May 31;173(6):1549
pubmed: 29856958
Cancer Cell. 2017 Jun 12;31(6):737-754.e6
pubmed: 28609654
Acta Neuropathol. 2015 Mar;129(3):449-57
pubmed: 25689980
Trends Genet. 2021 Mar;37(3):235-250
pubmed: 33272592
eNeuro. 2021 May 12;8(3):
pubmed: 33762301
Genesis. 2001 Oct;31(2):85-94
pubmed: 11668683
Cancer Lett. 2020 May 1;477:10-18
pubmed: 32112900
Cancer Res. 2017 Jul 15;77(14):3766-3777
pubmed: 28490517
Acta Biochim Biophys Sin (Shanghai). 2009 Apr;41(4):263-72
pubmed: 19352540
J Child Neurol. 2009 Nov;24(11):1418-30
pubmed: 19841429
Nature. 2012 Feb 15;482(7386):529-33
pubmed: 22343890
Genesis. 2003 Jul;36(3):158-61
pubmed: 12872247
J Clin Oncol. 2011 Apr 10;29(11):1408-14
pubmed: 20823417
Acta Neuropathol Commun. 2014 Jul 25;2:85
pubmed: 25059231
Cell Rep. 2020 Apr 14;31(2):107511
pubmed: 32294450
Nat Rev Cancer. 2012 Dec;12(12):818-34
pubmed: 23175120
Cancer Res. 2014 Apr 15;74(8):2351-61
pubmed: 24599127
Nat Genet. 2002 Sep;32(1):128-34
pubmed: 12185368
Genome Biol. 2014;15(12):550
pubmed: 25516281
J Cancer. 2021 Jan 15;12(6):1592-1603
pubmed: 33613746
Mol Cancer Res. 2021 May;19(5):743-752
pubmed: 33608450
Oncogene. 2020 Feb;39(9):2024-2026
pubmed: 31745295
Annu Rev Neurosci. 2022 Jul 8;45:515-531
pubmed: 35440142
EMBO Mol Med. 2019 Aug;11(8):e9830
pubmed: 31328883
Lancet Oncol. 2017 Jul;18(7):958-971
pubmed: 28545823
Cancer Res. 2013 Sep 1;73(17):5381-90
pubmed: 23852537
Int J Mol Sci. 2022 Mar 31;23(7):
pubmed: 35409206
Cancer Cell. 2014 Mar 17;25(3):393-405
pubmed: 24651015
Mol Cancer Res. 2021 Nov;19(11):1831-1839
pubmed: 34330843
Int J Oncol. 2006 Dec;29(6):1349-57
pubmed: 17088972
Nat Rev Mol Cell Biol. 2012 Oct;13(10):616-30
pubmed: 22992590
Development. 2016 Mar 1;143(5):810-21
pubmed: 26932671
Cell Rep. 2012 Aug 30;2(2):386-96
pubmed: 22884371
Development. 2006 May;133(9):1811-21
pubmed: 16571625
Gene. 2017 Sep 5;627:337-342
pubmed: 28669924
Nat Rev Cancer. 2015 Jun;15(6):334-46
pubmed: 25998713
Nature. 2017 Jul 19;547(7663):311-317
pubmed: 28726821
Nature. 2012 Aug 2;488(7409):100-5
pubmed: 22832583
J Biol Chem. 2014 Nov 21;289(47):32742-56
pubmed: 25288800
Front Oncol. 2021 Jun 14;11:694320
pubmed: 34195095
Cancer Cell. 2008 Aug 12;14(2):123-34
pubmed: 18691547
Development. 2005 May;132(10):2425-39
pubmed: 15843415
Acta Neuropathol. 2012 Apr;123(4):473-84
pubmed: 22358457
Curr Protoc Mol Biol. 2015 Jan 05;109:21.29.1-21.29.9
pubmed: 25559105
Nat Commun. 2018 Oct 8;9(1):4121
pubmed: 30297829
Nat Rev Neurol. 2012 May 08;8(6):340-51
pubmed: 22565209
Curr Opin Oncol. 2013 Nov;25(6):674-81
pubmed: 24076581
Mol Cell. 2018 Jun 7;70(5):825-841.e6
pubmed: 29861161
Neural Dev. 2011 Jun 20;6:29
pubmed: 21689430
Science. 2020 Jul 17;369(6501):276-282
pubmed: 32675368
Cell. 2007 Jul 13;130(1):77-88
pubmed: 17632057
Cancer Discov. 2012 May;2(5):401-4
pubmed: 22588877
Acta Neuropathol. 2014;127(6):931-3
pubmed: 24699697
Acta Neuropathol. 2012 Apr;123(4):465-72
pubmed: 22134537
Nat Methods. 2013 Dec;10(12):1213-8
pubmed: 24097267
J Neurosurg Pediatr. 2019 Feb 15;:1-9
pubmed: 30771762
J Neurooncol. 2020 Jan;146(1):25-39
pubmed: 31754919
Sci Rep. 2020 Jan 10;10(1):148
pubmed: 31924815
Genome Biol. 2008;9(9):R137
pubmed: 18798982
Cancer Res. 2012 Oct 1;72(19):4944-53
pubmed: 22875024
Nat Genet. 1999 Sep;23(1):99-103
pubmed: 10471508
Nucleic Acids Res. 2019 Jan 25;47(2):607-620
pubmed: 30335158
Dev Dyn. 2005 Nov;234(3):633-50
pubmed: 16145671
Mol Cell. 2010 May 28;38(4):576-89
pubmed: 20513432
J Neurooncol. 2016 Feb;126(3):415-24
pubmed: 26518543
Cancer Cell. 2014 Jul 14;26(1):33-47
pubmed: 24954133
Cold Spring Harb Perspect Med. 2013 Nov 01;3(11):
pubmed: 24186490
Future Oncol. 2016 Jan;12(1):107-17
pubmed: 26617331
J Biomed Sci. 2012 Dec 14;19:102
pubmed: 23241400
Cancer Res. 2006 Oct 15;66(20):10171-8
pubmed: 17047082
Gene Expr. 2003;11(3-4):181-97
pubmed: 14686790
Mol Brain. 2015 Apr 12;8:25
pubmed: 25888505
Cancer Cell. 2018 Sep 10;34(3):396-410.e8
pubmed: 30205044
Brain Pathol. 2020 May;30(3):691-702
pubmed: 31883407
Cancer Res. 2013 Jun 15;73(12):3796-807
pubmed: 23596255
Expert Rev Neurother. 2012 Jul;12(7):871-84
pubmed: 22853794
Nucleic Acids Res. 2014 Jul;42(Web Server issue):W187-91
pubmed: 24799436
Science. 2011 Jan 28;331(6016):435-9
pubmed: 21163964
Science. 2009 Dec 4;326(5958):1424-7
pubmed: 19965762
Clin Cancer Res. 2008 Feb 15;14(4):971-6
pubmed: 18281528
Nature. 2012 Aug 2;488(7409):106-10
pubmed: 22820256
Cancer Cell. 2012 Feb 14;21(2):168-80
pubmed: 22340591
Elife. 2013 Dec 24;2:e01503
pubmed: 24368734
Front Oncol. 2019 Sep 20;9:904
pubmed: 31616629
Stem Cells. 2011 Jan;29(1):20-31
pubmed: 21280156
Sci Signal. 2013 Apr 02;6(269):pl1
pubmed: 23550210
Nat Commun. 2021 Mar 19;12(1):1749
pubmed: 33741928
Nat Methods. 2017 Oct;14(10):959-962
pubmed: 28846090
J Psychiatr Res. 2014 Aug;55:87-95
pubmed: 24768109
Acta Neuropathol. 2011 Aug;122(2):231-40
pubmed: 21681522
AJNR Am J Neuroradiol. 2022 Jul;43(7):928-937
pubmed: 35710121
J Neurooncol. 2017 Nov;135(2):353-360
pubmed: 28808827
Nature. 2010 Dec 23;468(7327):1095-9
pubmed: 21150899
J Clin Oncol. 2011 Apr 10;29(11):1424-30
pubmed: 21098324
Nat Methods. 2012 Jul;9(7):671-5
pubmed: 22930834
Bioinformatics. 2010 Mar 15;26(6):841-2
pubmed: 20110278
Neural Dev. 2019 Feb 14;14(1):4
pubmed: 30764875
Dev Biol. 2004 Jun 15;270(2):393-410
pubmed: 15183722
AJNR Am J Neuroradiol. 2014 Jul;35(7):1263-9
pubmed: 24831600
J Vis Exp. 2018 Jul 28;(137):
pubmed: 30102289
Annu Rev Pathol. 2008;3:341-65
pubmed: 18039127
Acc Chem Res. 2020 Nov 17;53(11):2534-2545
pubmed: 33074649