CP110 and CEP135 localize near the proximal and distal centrioles of cattle and human spermatozoa.
Journal
microPublication biology
ISSN: 2578-9430
Titre abrégé: MicroPubl Biol
Pays: United States
ID NLM: 101759238
Informations de publication
Date de publication:
2023
2023
Historique:
received:
08
08
2023
revised:
07
09
2023
accepted:
22
09
2023
medline:
12
10
2023
pubmed:
12
10
2023
entrez:
12
10
2023
Statut:
epublish
Résumé
Centrosomes play an important role in the microtubule organization of a cell. The sperm's specialized centrosome consists of the canonical barrel-shaped proximal centriole, the funnel-shaped distal centriole, and the pericentriolar material known as striated columns (or segmented columns). Here, we examined the localization of the centriole proteins CEP135 and CP110 in cattle and human spermatozoa. In canonical centrioles, CP110 is a centriole tip protein that controls cilia formation, while CEP135 is a structural protein essential for constructing the centriole. In contrast, we found antibodies recognizing CEP135 and CP110 label near the proximal and distal centrioles at the expected location of the striated columns and capitulum in cattle and humans in an antibody and species-specific way. These findings provide a pathway to understanding the unique functions of spermatozoan centrosome.
Identifiants
pubmed: 37822686
doi: 10.17912/micropub.biology.000951
pmc: PMC10562935
doi:
Types de publication
Journal Article
Langues
eng
Informations de copyright
Copyright: © 2023 by the authors.
Déclaration de conflit d'intérêts
The authors declare that there are no conflicts of interest present.
Références
Gene. 2017 Oct 30;633:48-53
pubmed: 28866084
Philos Trans R Soc Lond B Biol Sci. 2014 Sep 5;369(1650):
pubmed: 25047611
Nat Commun. 2018 Jun 7;9(1):2210
pubmed: 29880810
Dev Cell. 2007 Aug;13(2):190-202
pubmed: 17681131
Reproduction. 2019 Feb;157(2):R33-R51
pubmed: 30496124
Cilia. 2013 Jul 26;2(1):9
pubmed: 24053599
Curr Biol. 2016 Dec 5;26(23):3183-3189
pubmed: 28094036
Nat Med. 1995 Jan;1(1):47-52
pubmed: 7584952
Mol Biol Cell. 2012 Dec;23(24):4820-32
pubmed: 23115304
Biol Reprod. 2020 Apr 24;102(5):988-998
pubmed: 31995163
MicroPubl Biol. 2022 Nov 12;2022:
pubmed: 36444375
Mol Biol Cell. 2009 May;20(10):2605-14
pubmed: 19321663
Mol Biol Evol. 2002 Nov;19(11):1973-80
pubmed: 12411606
Andrology. 2023 Oct;11(7):1418-1436
pubmed: 36896575
Histochem Cell Biol. 2008 Jun;129(6):667-86
pubmed: 18437411
Bioessays. 2018 Apr;40(4):e1700241
pubmed: 29508910
Cells. 2021 Aug 31;10(9):
pubmed: 34571916
Nature. 2021 Aug;596(7873):583-589
pubmed: 34265844
Nucleic Acids Res. 2022 Jan 7;50(D1):D439-D444
pubmed: 34791371
Cells. 2023 May 07;12(9):
pubmed: 37174735
Anat Rec. 1969 Oct;165(2):153-64
pubmed: 5387815
Mol Cell Endocrinol. 2020 Dec 1;518:110987
pubmed: 32810575
J Mol Cell Biol. 2021 Dec 6;13(9):611-621
pubmed: 34264337
Development. 2016 May 1;143(9):1491-501
pubmed: 26965371
Eur J Cell Biol. 2022 Jun-Aug;101(3):151243
pubmed: 35640396
Curr Top Dev Biol. 2000;49:343-63
pubmed: 11005027
J Assist Reprod Genet. 2021 Aug;38(8):2097-2105
pubmed: 33786733
Nat Commun. 2021 Jun 21;12(1):3808
pubmed: 34155206
EMBO J. 2022 Oct 17;41(20):e104582
pubmed: 36093892
Cells. 2019 Jul 10;8(7):
pubmed: 31295970
Philos Trans R Soc Lond B Biol Sci. 2014 Sep 5;369(1650):
pubmed: 25047614
Hum Reprod Update. 2018 Sep 1;24(5):535-555
pubmed: 29800303
Cell Div. 2022 Feb 14;17(1):1
pubmed: 35164835
J Cell Biol. 2022 Jan 3;221(1):
pubmed: 34813648
EMBO J. 2021 Apr 1;40(7):e107410
pubmed: 33694216