Perfusion Collateral Index versus Hypoperfusion Intensity Ratio in Assessment of Collaterals in Patients with Acute Ischemic Stroke.
Journal
AJNR. American journal of neuroradiology
ISSN: 1936-959X
Titre abrégé: AJNR Am J Neuroradiol
Pays: United States
ID NLM: 8003708
Informations de publication
Date de publication:
11 2023
11 2023
Historique:
received:
14
05
2023
accepted:
20
08
2023
pmc-release:
01
11
2024
medline:
10
11
2023
pubmed:
13
10
2023
entrez:
12
10
2023
Statut:
ppublish
Résumé
Perfusion-based collateral indices such as the perfusion collateral index and the hypoperfusion intensity ratio have shown promise in the assessment of collaterals in patients with acute ischemic stroke. We aimed to compare the diagnostic performance of the perfusion collateral index and the hypoperfusion intensity ratio in collateral assessment compared with angiographic collaterals and outcome measures, including final infarct volume, infarct growth, and functional independence. Consecutive patients with acute ischemic stroke with anterior circulation proximal arterial occlusion who underwent endovascular thrombectomy and had pre- and posttreatment MRI were included. Using pretreatment MR perfusion, we calculated the perfusion collateral index and the hypoperfusion intensity ratio for each patient. The angiographic collaterals obtained from DSA were dichotomized to sufficient (American Society of Interventional and Therapeutic Neuroradiology [ASITN] scale 3-4) versus insufficient (ASITN scale 0-2). The association of collateral status determined by the perfusion collateral index and the hypoperfusion intensity ratio was assessed against angiographic collaterals and outcome measures. A total of 98 patients met the inclusion criteria. Perfusion collateral index values were significantly higher in patients with sufficient angiographic collaterals ( Results show that the perfusion collateral index outperforms the hypoperfusion intensity ratio in the assessment of collateral status, infarct growth, and determination of functional outcomes.
Sections du résumé
BACKGROUND AND PURPOSE
Perfusion-based collateral indices such as the perfusion collateral index and the hypoperfusion intensity ratio have shown promise in the assessment of collaterals in patients with acute ischemic stroke. We aimed to compare the diagnostic performance of the perfusion collateral index and the hypoperfusion intensity ratio in collateral assessment compared with angiographic collaterals and outcome measures, including final infarct volume, infarct growth, and functional independence.
MATERIALS AND METHODS
Consecutive patients with acute ischemic stroke with anterior circulation proximal arterial occlusion who underwent endovascular thrombectomy and had pre- and posttreatment MRI were included. Using pretreatment MR perfusion, we calculated the perfusion collateral index and the hypoperfusion intensity ratio for each patient. The angiographic collaterals obtained from DSA were dichotomized to sufficient (American Society of Interventional and Therapeutic Neuroradiology [ASITN] scale 3-4) versus insufficient (ASITN scale 0-2). The association of collateral status determined by the perfusion collateral index and the hypoperfusion intensity ratio was assessed against angiographic collaterals and outcome measures.
RESULTS
A total of 98 patients met the inclusion criteria. Perfusion collateral index values were significantly higher in patients with sufficient angiographic collaterals (
CONCLUSIONS
Results show that the perfusion collateral index outperforms the hypoperfusion intensity ratio in the assessment of collateral status, infarct growth, and determination of functional outcomes.
Identifiants
pubmed: 37827719
pii: ajnr.A8002
doi: 10.3174/ajnr.A8002
pmc: PMC10631520
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1249-1255Informations de copyright
© 2023 by American Journal of Neuroradiology.
Références
Radiology. 2015 May;275(2):510-20
pubmed: 25633505
Stroke. 2003 Aug;34(8):e109-37
pubmed: 12869717
IEEE Trans Med Imaging. 2004 Jul;23(7):881-90
pubmed: 15250640
Stroke. 1999 Feb;30(2):293-8
pubmed: 9933262
J Cereb Blood Flow Metab. 2013 Mar;33(3):365-71
pubmed: 23149554
Curr Opin Neurol. 2015 Feb;28(1):10-5
pubmed: 25514251
Stroke. 2016 Feb;47(2):531-4
pubmed: 26658445
Eur J Neurol. 2020 May;27(5):864-870
pubmed: 32068938
World Neurosurg. 2019 Mar;123:e797-e802
pubmed: 30590217
Stroke. 2010 Oct;41(10):2316-22
pubmed: 20829514
Stroke. 2019 Dec;50(12):e344-e418
pubmed: 31662037
IEEE Trans Med Imaging. 2012 Jul;31(7):1381-95
pubmed: 22410325
J Neuroradiol. 2022 Mar;49(2):198-204
pubmed: 34800563
Stroke. 2011 May;42(5):1276-81
pubmed: 21454821
AJNR Am J Neuroradiol. 2016 Nov;37(11):2037-2042
pubmed: 27418474
JAMA Netw Open. 2021 Nov 1;4(11):e2132376
pubmed: 34739060
Stroke. 2003 Sep;34(9):2279-84
pubmed: 12881609
J Neuroimaging. 2015 Nov-Dec;25(6):969-77
pubmed: 26082023
AJNR Am J Neuroradiol. 2005 Aug;26(7):1789-97
pubmed: 16091531
J Clin Med. 2021 Mar 21;10(6):
pubmed: 33801050
Int J Stroke. 2019 Aug;14(6):603-612
pubmed: 31096871
Stroke. 2014 Apr;45(4):1018-23
pubmed: 24595591
Brain Sci. 2022 Sep 02;12(9):
pubmed: 36138917
J Comput Assist Tomogr. 2020 Nov/Dec;44(6):984-992
pubmed: 33196604
J Cereb Blood Flow Metab. 2018 Oct;38(10):1839-1847
pubmed: 29135347
Neurology. 2002 Nov 12;59(9):1381-7
pubmed: 12427888
AJNR Am J Neuroradiol. 2015 Feb;36(2):275-82
pubmed: 25500313
Stroke. 2013 Oct;44(10):2748-54
pubmed: 23887836
AJNR Am J Neuroradiol. 2011 Oct;32(9):1640-5
pubmed: 21799045
AJNR Am J Neuroradiol. 2008 Mar;29(3):582-7
pubmed: 18337393
AJNR Am J Neuroradiol. 2018 Feb;39(2):219-225
pubmed: 29217747
AJNR Am J Neuroradiol. 2021 Aug;42(8):1380-1386
pubmed: 34140276
Radiology. 2020 Apr;295(1):192-201
pubmed: 32068506
Ann Neurol. 2018 Oct;84(4):616-620
pubmed: 30168180