Comparison of Two Methods for Estimating MS-Related Mortality: The Excess Mortality vs. the Cause-Specific Frameworks.
cause-specific
excess hazard
multiple sclerosis
observational study
probability of death
Journal
Neurology
ISSN: 1526-632X
Titre abrégé: Neurology
Pays: United States
ID NLM: 0401060
Informations de publication
Date de publication:
12 Oct 2023
12 Oct 2023
Historique:
received:
17
07
2023
accepted:
11
09
2023
medline:
13
10
2023
pubmed:
13
10
2023
entrez:
12
10
2023
Statut:
aheadofprint
Résumé
Determining whether multiple sclerosis (MS) causes death is challenging. Our objective was to contrast two frameworks to estimate probabilities of death attributed to MS (P We used data from the In the comparative subset, the estimated 30-year P EMF has the strong advantage of not requiring death certificates, which quality is sub-optimal. Conceptually, it also appears more relevant as it avoids having to state, for each individual, if death was directly or indirectly caused by MS or if it would have occurred anyway, which is especially difficult in such chronic diseases.
Sections du résumé
BACKGROUND AND OBJECTIVE
OBJECTIVE
Determining whether multiple sclerosis (MS) causes death is challenging. Our objective was to contrast two frameworks to estimate probabilities of death attributed to MS (P
METHODS
METHODS
We used data from the
RESULTS
RESULTS
In the comparative subset, the estimated 30-year P
DISCUSSION
CONCLUSIONS
EMF has the strong advantage of not requiring death certificates, which quality is sub-optimal. Conceptually, it also appears more relevant as it avoids having to state, for each individual, if death was directly or indirectly caused by MS or if it would have occurred anyway, which is especially difficult in such chronic diseases.
Identifiants
pubmed: 37827849
pii: WNL.0000000000207925
doi: 10.1212/WNL.0000000000207925
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2023 American Academy of Neurology. Unauthorized reproduction of this article is prohibited.