Tailored interventions to improve adherence to medication in elderly patients with Parkinson's disease: a study protocol for a randomized controlled trial (AdhCare).
Adherence
Chronic diseases
Intervention
Medication
Parkinson’s disease
Randomization
Journal
Trials
ISSN: 1745-6215
Titre abrégé: Trials
Pays: England
ID NLM: 101263253
Informations de publication
Date de publication:
12 Oct 2023
12 Oct 2023
Historique:
received:
20
06
2023
accepted:
19
09
2023
medline:
1
11
2023
pubmed:
13
10
2023
entrez:
12
10
2023
Statut:
epublish
Résumé
Nonadherence to medication is a major issue in patients with chronic disorders such as Parkinson's disease (PD). Many interventions for increasing adherence have been tested, and these have shown weak-to-moderate efficiency. Although the best methods to improve adherence remain unclear, it is reasonable to use tailored interventions instead of the "one-size-fits-all" approach. A randomized, controlled, triple-blinded trial in elderly patients with PD is conducted to test the efficacy of AdhCare, a tailored intervention to enhance adherence compared with that achieved with routine care (64 participants per arm). Motor function, quality of life, and adherence measures will be assessed at baseline and at 3 and 6 months of follow-up. The type of intervention depends on the main personal reason for nonadherence (e.g., forgetting to take the medication or poor knowledge about the medication). The results of this study will provide valuable information for health professionals and policymakers on the effectiveness of tailored interventions in elderly patients with PD. German Clinical Trials Register DRKS00023655. Registered on 24 February 2021. Last update on 22 March 2023.
Sections du résumé
BACKGROUND
BACKGROUND
Nonadherence to medication is a major issue in patients with chronic disorders such as Parkinson's disease (PD). Many interventions for increasing adherence have been tested, and these have shown weak-to-moderate efficiency. Although the best methods to improve adherence remain unclear, it is reasonable to use tailored interventions instead of the "one-size-fits-all" approach.
METHODS
METHODS
A randomized, controlled, triple-blinded trial in elderly patients with PD is conducted to test the efficacy of AdhCare, a tailored intervention to enhance adherence compared with that achieved with routine care (64 participants per arm). Motor function, quality of life, and adherence measures will be assessed at baseline and at 3 and 6 months of follow-up. The type of intervention depends on the main personal reason for nonadherence (e.g., forgetting to take the medication or poor knowledge about the medication).
DISCUSSION
CONCLUSIONS
The results of this study will provide valuable information for health professionals and policymakers on the effectiveness of tailored interventions in elderly patients with PD.
TRIAL REGISTRATION
BACKGROUND
German Clinical Trials Register DRKS00023655. Registered on 24 February 2021. Last update on 22 March 2023.
Identifiants
pubmed: 37828583
doi: 10.1186/s13063-023-07663-9
pii: 10.1186/s13063-023-07663-9
pmc: PMC10571350
doi:
Types de publication
Clinical Trial Protocol
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
668Subventions
Organisme : Deutsche Forschungsgemeinschaft
ID : 413668513
Organisme : Bundesministerium für Bildung und Forschung
ID : 01GY1804
Informations de copyright
© 2023. BioMed Central Ltd., part of Springer Nature.
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