Urodynamic findings in children with primary refractory nocturnal enuresis: 10 years' experience of a tertiary center.

MNE NMNE UDS enuresis urodynamic study

Journal

Health science reports
ISSN: 2398-8835
Titre abrégé: Health Sci Rep
Pays: United States
ID NLM: 101728855

Informations de publication

Date de publication:
Oct 2023
Historique:
received: 12 04 2023
revised: 22 09 2023
accepted: 27 09 2023
medline: 13 10 2023
pubmed: 13 10 2023
entrez: 13 10 2023
Statut: epublish

Résumé

To identify correlations between urodynamic study (UDS) findings and urinary symptoms in children with refractory monosymptomatic and nonmonosymptomatic primary nocturnal enuresis. A total of 96 neurologically normal children were enrolled, 44 consecutive boys and 51 consecutive girls, aged 5-18 years, of whom 41 (38.8%) had refractory monosymptomatic nocturnal enuresis (MNE) and 55 (61.2%) had refractory non-MNE (NMNE). We assessed the urodynamics of all children to detect any underlying bladder overactivity. A comparative analysis was carried out between the two groups of patients. Detrusor overactivity (DO), low bladder capacity, low compliance, and increased postvoid residual (PVR) were identified in 70 (72.9%), 35 (36.5%), 43, and 76 (79.2%) patients, respectively. The mean bladder compliance was 21.66 ± 14.52 mL/cmH There was a high prevalence of bladder function disorders in both refractory MNE and NMNE patients in our study. This included small functional capacity, low bladder compliance, and marked DO. A nocturnal enuresis may be the only presenting symptom, however, it may be associated with bladder overactivity, UTI, and constipation; the UDS findings may aid in guiding the assessment and treatment of children suffering from primary refractory nocturnal enuresis and its association with bladder and bowel symptoms.

Sections du résumé

Background/Aim UNASSIGNED
To identify correlations between urodynamic study (UDS) findings and urinary symptoms in children with refractory monosymptomatic and nonmonosymptomatic primary nocturnal enuresis.
Materials and Methods UNASSIGNED
A total of 96 neurologically normal children were enrolled, 44 consecutive boys and 51 consecutive girls, aged 5-18 years, of whom 41 (38.8%) had refractory monosymptomatic nocturnal enuresis (MNE) and 55 (61.2%) had refractory non-MNE (NMNE). We assessed the urodynamics of all children to detect any underlying bladder overactivity. A comparative analysis was carried out between the two groups of patients.
Results UNASSIGNED
Detrusor overactivity (DO), low bladder capacity, low compliance, and increased postvoid residual (PVR) were identified in 70 (72.9%), 35 (36.5%), 43, and 76 (79.2%) patients, respectively. The mean bladder compliance was 21.66 ± 14.52 mL/cmH
Conclusion UNASSIGNED
There was a high prevalence of bladder function disorders in both refractory MNE and NMNE patients in our study. This included small functional capacity, low bladder compliance, and marked DO. A nocturnal enuresis may be the only presenting symptom, however, it may be associated with bladder overactivity, UTI, and constipation; the UDS findings may aid in guiding the assessment and treatment of children suffering from primary refractory nocturnal enuresis and its association with bladder and bowel symptoms.

Identifiants

pubmed: 37829504
doi: 10.1002/hsr2.1626
pii: HSR21626
pmc: PMC10565087
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e1626

Informations de copyright

© 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

Int Neurourol J. 2021 Sep;25(3):236-243
pubmed: 33676380
Pediatr Nephrol. 2018 Dec;33(12):2207-2219
pubmed: 28975420
Front Pediatr. 2016 Oct 03;4:101
pubmed: 27752507
Eur Urol Focus. 2017 Apr;3(2-3):198-206
pubmed: 28888814
Int J Urol. 2006 Jan;13(1):36-41
pubmed: 16448430
Int J Urol. 2017 Mar;24(3):174-182
pubmed: 28208214
Urology. 2023 Sep 9;:
pubmed: 37696309
J Pediatr Urol. 2023 Feb;19(1):6-18
pubmed: 37310191
BJU Int. 2001 Jun;87(9):760-6
pubmed: 11412210
J Pediatr Urol. 2018 Apr;14(2):160.e1-160.e6
pubmed: 29174376
Gastroenterol Res Pract. 2018 Feb 27;2018:3108021
pubmed: 29681930
Arch Iran Med. 2012 Nov;15(11):702-6
pubmed: 23102248
Int J Environ Res Public Health. 2019 Apr 11;16(7):
pubmed: 30978908
BMC Pediatr. 2020 Jun 22;20(1):305
pubmed: 32571248
World J Urol. 2017 Mar;35(3):459-465
pubmed: 27306687
Indian Pediatr. 2012 May;49(5):401-3
pubmed: 22700665
Neurourol Urodyn. 2018 Nov;37(8):2311-2314
pubmed: 29931789
Expert Rev Gastroenterol Hepatol. 2020 Jan;14(1):39-46
pubmed: 31893959
Neurourol Urodyn. 2020 Feb;39(2):688-694
pubmed: 31804751
Investig Clin Urol. 2021 May;62(3):331-339
pubmed: 33834643
Turk J Med Sci. 2015;45(2):320-4
pubmed: 26084121
Neurourol Urodyn. 2014 Jun;33(5):482-7
pubmed: 23775924
Dtsch Arztebl Int. 2019 Apr 19;116(16):279-285
pubmed: 31159915
BJU Int. 2002 Aug;90(3):302-7
pubmed: 12133069
Arch Psychiatr Nurs. 2017 Jun;31(3):319-323
pubmed: 28499575
Urology. 2012 Feb;79(2):421-4
pubmed: 22173180

Auteurs

Farzaneh Sharifiaghdas (F)

Department of Urology, Shahid Labbafinejad Medical Center, Urology and Nephrology Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

Behzad Narouie (B)

Department of Urology Zahedan University of Medical Sciences Zahedan Iran.

Mohadese Ahmadzade (M)

Department of Urology, Shahid Labbafinejad Medical Center, Urology and Nephrology Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

Hamidreza Rouientan (H)

Department of Urology, Shahid Labbafinejad Medical Center, Urology and Nephrology Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

Darya Najafi (D)

Department of Urology, Shahid Labbafinejad Medical Center, Urology and Nephrology Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

Mehdi Dadpour (M)

Department of Urology, Shahid Labbafinejad Medical Center, Urology and Nephrology Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

Nariman Latifi (N)

Department of Urology, Shahid Labbafinejad Medical Center, Urology and Nephrology Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

Hamideh Hanafi Bojd (H)

Department of Urology, Shahid Labbafinejad Medical Center, Urology and Nephrology Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

Sobhan Sabzi (S)

Department of Urology, Shahid Labbafinejad Medical Center, Urology and Nephrology Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.

Classifications MeSH