Solvent-Induced Raynaud's Phenomenon.
iloprost
occupational risk
raynaud’s phenomenon
secondary raynaud’s phenomenon
solvent exposure
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
accepted:
10
09
2023
medline:
13
10
2023
pubmed:
13
10
2023
entrez:
13
10
2023
Statut:
epublish
Résumé
Raynaud's phenomenon (RP) is a vasospastic disorder characterized by an exaggerated vasoconstrictive response to cold or emotional stress. It can be classified as primary (PRP) or secondary (SRP) depending on its association with an underlying condition. We present a case of a young female with severe RP, with trophic changes and abnormal capillaroscopy. After a detailed investigation, a diagnosis of secondary RP due to solvent exposure was made. The patient was treated with calcium channel blocker in low doses, due to hypotension, without improvement of symptoms. Vitamin C and pentoxifylline were added with an unsatisfactory response. Given the progressive worsening of RP and the appearance of trophic lesions, the patient's treatment was reviewed, and continuous intravenous iloprost infusion through an elastomeric pump was started. This resulted in significant symptom improvement and normalization on the capillaroscopic examination.
Identifiants
pubmed: 37829986
doi: 10.7759/cureus.45004
pmc: PMC10565523
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e45004Informations de copyright
Copyright © 2023, Rodrigues et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Front Pharmacol. 2016 Nov 16;7:438
pubmed: 27899893
Occup Environ Med. 2002 Aug;59(8):545-9
pubmed: 12151611
J Rheumatol. 2011 Sep;38(9):1940-6
pubmed: 21677001
Rheumatology (Oxford). 2005 May;44(5):587-96
pubmed: 15741200
Vasa. 2017 Oct;46(6):413-423
pubmed: 28895508
PLoS One. 2012;7(12):e51506
pubmed: 23284705
Rheum Dis Clin North Am. 1990 Feb;16(1):75-91
pubmed: 2406812
J Autoimmun. 2014 Feb-Mar;48-49:60-5
pubmed: 24491823
BMJ Open. 2015 Mar 16;5(3):e006389
pubmed: 25776043
Lancet. 2001 Jun 23;357(9273):2042-8
pubmed: 11438158
Ann Rheum Dis. 2017 Aug;76(8):1327-1339
pubmed: 27941129
J Rheumatol. 2005 Sep;32(9):1713-8
pubmed: 16142866
Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1955-61
pubmed: 17644575
Am J Epidemiol. 2003 Mar 15;157(6):493-500
pubmed: 12631538
Alcohol Alcohol. 2010 Jul-Aug;45(4):347-55
pubmed: 20522422
Vasc Med. 2021 Feb;26(1):56-70
pubmed: 33566754
Nat Rev Rheumatol. 2015 Mar;11(3):146-58
pubmed: 25536485