NAD

DNA damage NAD booster PARP mustard agents nicotinamide adenine dinucleotide nicotinamide riboside poly(ADP-ribosylation) sulfur mustard

Journal

Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052

Informations de publication

Date de publication:
02 10 2023
Historique:
received: 24 08 2023
revised: 20 09 2023
accepted: 25 09 2023
medline: 23 10 2023
pubmed: 13 10 2023
entrez: 13 10 2023
Statut: epublish

Résumé

Sulfur mustard (SM) and its derivatives are potent genotoxic agents, which have been shown to trigger the activation of poly (ADP-ribose) polymerases (PARPs) and the depletion of their substrate, nicotinamide adenine dinucleotide (NAD

Identifiants

pubmed: 37830610
pii: cells12192396
doi: 10.3390/cells12192396
pmc: PMC10572126
pii:
doi:

Substances chimiques

2-chloroethyl ethyl sulfide 693-07-2
Alkylating Agents 0
NAD 0U46U6E8UK
Poly(ADP-ribose) Polymerases EC 2.4.2.30
DNA 9007-49-2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Joanna Ruszkiewicz (J)

Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.

Ylea Papatheodorou (Y)

Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.

Nathalie Jäck (N)

Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.

Jasmin Melzig (J)

Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.

Franziska Eble (F)

Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.

Annika Pirker (A)

Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.

Marius Thomann (M)

Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.

Andreas Haberer (A)

Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.

Simone Rothmiller (S)

Bundeswehr Institute of Pharmacology and Toxicology, 80937 Munich, Germany.

Alexander Bürkle (A)

Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.

Aswin Mangerich (A)

Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.
Nutritional Toxicology, Institute Nutritional Science, University of Potsdam, 14469 Potsdam, Germany.

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Classifications MeSH