Well-being trajectories in breast cancer and their predictors: A machine-learning approach.


Journal

Psycho-oncology
ISSN: 1099-1611
Titre abrégé: Psychooncology
Pays: England
ID NLM: 9214524

Informations de publication

Date de publication:
11 2023
Historique:
revised: 29 09 2023
received: 02 06 2023
accepted: 02 10 2023
medline: 8 11 2023
pubmed: 13 10 2023
entrez: 13 10 2023
Statut: ppublish

Résumé

This study aimed to describe distinct trajectories of anxiety/depression symptoms and overall health status/quality of life over a period of 18 months following a breast cancer diagnosis, and identify the medical, socio-demographic, lifestyle, and psychological factors that predict these trajectories. 474 females (mean age = 55.79 years) were enrolled in the first weeks after surgery or biopsy. Data from seven assessment points over 18 months, at 3-month intervals, were used. The two outcomes were assessed at all points. Potential predictors were assessed at baseline and the first follow-up. Machine-Learning techniques were used to detect latent patterns of change and identify the most important predictors. Five trajectories were identified for each outcome: stably high, high with fluctuations, recovery, deteriorating/delayed response, and stably poor well-being (chronic distress). Psychological factors (i.e., negative affect, coping, sense of control, social support), age, and a few medical variables (e.g., symptoms, immune-related inflammation) predicted patients' participation in the delayed response and the chronic distress trajectories versus all other trajectories. There is a strong possibility that resilience does not always reflect a stable response pattern, as there might be some interim fluctuations. The use of machine-learning techniques provides a unique opportunity for the identification of illness trajectories and a shortlist of major bio/behavioral predictors. This will facilitate the development of early interventions to prevent a significant deterioration in patient well-being.

Identifiants

pubmed: 37830776
doi: 10.1002/pon.6230
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1762-1770

Informations de copyright

© 2023 John Wiley & Sons Ltd.

Références

Mansano-Schlosser TC, Ceolim MF, Valerio TD. Poor sleep quality, depression and hope before breast cancer surgery. Appl Nurs Res. 2017;34:7-11. https://doi.org/10.1016/j.apnr.2016.11.010
Helgeson VS, Snyder P, Seltman H. Psychological and physical adjustment to breast cancer over 4 years: identifying distinct trajectories of change. Health Psychol. 2004;23(1):3-15. https://doi.org/10.1037/0278-6133.23.1.3
Roine E, Sintonen H, Kellokumpu-Lehtinen PL, et al. Long-term health-related quality of life of breast cancer survivors remains impaired compared to the age-matched general population especially in young women. Results from the prospective controlled BREX exercise study. Breast. 2021;59:110-116. https://doi.org/10.1016/j.breast.2021.06.012
Bonanno GA. Loss, trauma, and human resilience: have we underestimated the human capacity to thrive after extremely aversive events? Am Psychol. 2004;59(1):20-28. https://doi.org/10.1037/0003-066X.59.1.20
Leventhal H, Halm E, Horowitz C, Leventhal EA, Ozakinci G. Living with chronic illness: a contextualized, self-regulation approach. In: Sutton S, Baum A, Johnston M, eds. The SAGE Handbook of Health Psychology. Sage; 2005:197-240.
Leventhal H, Yu JS, Leventhal EA, Bodnar-Deren SM. Cognitive mechanisms and common-sense management of cancer risk: do patients make decisions? In: Diefenbach MA, Miller-Halegoua S, Bowen DJ, eds. Handbook of Health Decision Science. Springer; 2016:87-108.
Dunn LB, Cooper BA, Neuhaus J, et al. Identification of distinct depressive symptom trajectories in women following surgery for breast cancer [published correction appears in Health Psychol. 2012 Mar;31(2):155]. Health Psychol. 2011;30(6):683-692. https://doi.org/10.1037/a0024366
Kant J, Czisch A, Schott S, Siewerdt-Werner D, Birkenfeld F, Keller M. Identifying and predicting distinct distress trajectories following a breast cancer diagnosis - from treatment into early survival. J Psychosom Res. 2018;115:6-13. https://doi.org/10.1016/j.jpsychores.2018.09.012
Lam WW, Soong I, Yau TK, et al. The evolution of psychological distress trajectories in women diagnosed with advanced breast cancer: a longitudinal study. Psycho Oncol. 2013;22(12):2831-2839. https://doi.org/10.1002/pon.3361
Saboonchi F, Petersson LM, Wennman-Larsen A, Alexanderson K, Vaez M. Trajectories of anxiety among women with breast cancer: a proxy for adjustment from acute to transitional survivorship. J Psychosoc Oncol. 2015;33(6):603-619. https://doi.org/10.1080/07347332.2015.1082165
Durá-Ferrandis E, Mandelblatt JS, Clapp J, et al. Personality, coping, and social support as predictors of long-term quality-of-life trajectories in older breast cancer survivors: CALGB protocol 369901 (Alliance). Psycho Oncol. 2017;26(11):1914-1921. https://doi.org/10.1002/pon.4404
Di Meglio A, Havas J, Gbenou AS, et al. Dynamics of long-term patient-reported quality of life and health behaviors after adjuvant breast cancer chemotherapy. J Clin Oncol. 2022;40(27):3190-3204. https://doi.org/10.1200/JCO.21.00277
Bower JE, Wiley J, Petersen L, Irwin MR, Cole SW, Ganz PA. Fatigue after breast cancer treatment: biobehavioral predictors of fatigue trajectories. Health Psychol. 2018;37(11):1025-1034. https://doi.org/10.1037/hea0000652
Seligman B, Tuljapurkar S, Rehkopf D. Machine learning approaches to the social determinants of health in the health and retirement study. SSM Popul Health. 2017;4:95-99. https://doi.org/10.1016/j.ssmph.2017.11.008
Verboon P, Pat-El R. Clustering longitudinal data using R: a Monte Carlo study. Methodol. 2022;18(2):144-163. https://doi.org/10.5964/meth.7143
Brandão T, Schulz MS, Matos PM. Psychological adjustment after breast cancer: a systematic review of longitudinal studies. Psycho Oncol. 2017;26(7):917-926. https://doi.org/10.1002/pon.4230
Hiensch AE, Bolam KA, Mijwel S, May AM, Wengström Y. Sense of coherence and its relationship to participation, cancer-related fatigue, symptom burden, and quality of life in women with breast cancer participating in the OptiTrain exercise trial. Support Care Cancer. 2020;28(11):5371-5379. https://doi.org/10.1007/s00520-020-05378-0
Pereira MA, Araújo A, Simões M, Costa C. Influence of psychological factors in breast and lung cancer risk - a systematic review. Front Psychol. 2022;12:769394. Published 2022 Jan 3. https://doi.org/10.3389/fpsyg.2021.769394
Swartzman S, Booth JN, Munro A, Sani F. Posttraumatic stress disorder after cancer diagnosis in adults: a meta-analysis. Depress Anxiety. 2017;34(4):327-339. https://doi.org/10.1002/da.22542
Chirico A, Lucidi F, Merluzzi T, et al. A meta-analytic review of the relationship of cancer coping self-efficacy with distress and quality of life. Oncotarget. 2017;8(22):36800-36811. https://doi.org/10.18632/oncotarget.15758
Lazarus RS, Folkman S. Stress, Appraisal, and Coping. Springer; 1984.
Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361-370. https://doi.org/10.1111/j.1600-0447.1983.tb09716.x
Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993;85(5):365-376. https://doi.org/10.1093/jnci/85.5.365
Sprangers MA, Groenvold M, Arraras JI, et al. The European Organization for Research and Treatment of Cancer breast cancer-specific quality-of-life questionnaire module: first results from a three-country field study. J Clin Oncol. 1996;14(10):2756-2768. https://doi.org/10.1200/JCO.1996.14.10.2756
Scheier MF, Carver CS, Bridges MW. Distinguishing optimism from neuroticism (and trait anxiety, self-mastery, and self-esteem): a reevaluation of the Life Orientation Test. J Pers Soc Psychol. 1994;67(6):1063-1078. https://doi.org/10.1037//0022-3514.67.6.1063
Antonovsky A. The structure and properties of the sense of coherence scale. Soc Sci Med. 1993;36(6):725-733. https://doi.org/10.1016/0277-9536(93)90033-z
Connor KM, Davidson JR. Development of a new resilience scale: the Connor-Davidson resilience scale (CD-RISC). Depress Anxiety. 2003;18(2):76-82. https://doi.org/10.1002/da.10113
Carlson LE, Brown KW. Validation of the mindful attention awareness scale in a cancer population. J Psychosom Res. 2005;58(1):29-33. https://doi.org/10.1016/j.jpsychores.2004.04.366
Watson M, Law M, dos Santos M, Greer S, Baruch J, Bliss J. The Mini-MAC: further development of the mental adjustment to cancer scale. J Psychosoc Oncol. 1994;12(3):33-46. https://doi.org/10.1300/J077V12N03_03
Bonanno GA, Pat-Horenczyk R, Noll J. Coping flexibility and trauma: the perceived ability to cope with trauma (PACT) scale. Psychol Trauma Theor Res Pract Pol. 2011;3(2):117-129. https://doi.org/10.1037/a0020921
Cann A, Calhoun LG, Tedeschi RG, et al. A short form of the posttraumatic growth inventory. Hist Philos Logic. 2010;23(2):127-137. https://doi.org/10.1080/10615800903094273
Moser A, Stuck AE, Silliman RA, Ganz PA, Clough-Gorr KM. The eight-item modified Medical Outcomes Study Social Support Survey: psychometric evaluation showed excellent performance. J Clin Epidemiol. 2012;65(10):1107-1116. https://doi.org/10.1016/j.jclinepi.2012.04.007
Faccio F, Gandini S, Renzi C, Fioretti C, Crico C, Pravettoni G. Development and validation of the Family Resilience (FaRE) Questionnaire: an observational study in Italy [published correction appears in BMJ Open. 2019 Sep 4;9(9):e024670corr1]. BMJ Open. 2019;9(6):e024670. Published 2019 Jun 5. https://doi.org/10.1136/bmjopen-2018-024670
Heitzmann CA, Merluzzi TV, Jean-Pierre P, Roscoe JA, Kirsh KL, Passik SD. Assessing self-efficacy for coping with cancer: development and psychometric analysis of the brief version of the Cancer Behavior Inventory (CBI-B). Psycho Oncol. 2011;20(3):302-312. https://doi.org/10.1002/pon.1735
Simard S, Savard J. Screening and comorbidity of clinical levels of fear of cancer recurrence. J Cancer Surviv. 2015;9(3):481-491. https://doi.org/10.1007/s11764-015-0424-4
Watson D, Clark LA, Tellegen A. Development and validation of brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol. 1988;54(6):1063-1070. https://doi.org/10.1037//0022-3514.54.6.1063
Garnefski N, Kraaij V. The Cognitive Emotion Regulation Questionnaire: psychometric features and prospective relationships with depression and anxiety in adults. Eur J Psychol Assess. 2007;23(3):141-149. https://doi.org/10.1027/1015-5759.23.3.141
Southwick SM, Bonanno GA, Masten AS, Panter-Brick C, Yehuda R. Resilience definitions, theory, and challenges: interdisciplinary perspectives. Eur J Psychotraumatol. 2014;5(1). https://doi.org/10.3402/ejpt.v5.25338
Stanton AL, Wiley JF, Krull JL, Crespi CM, Weihs KL. Cancer-related coping processes as predictors of depressive symptoms, trajectories, and episodes. J Consult Clin Psychol. 2018;86(10):820-830. https://doi.org/10.1037/ccp0000328
Tsunoda A, Nakao K, Hiratsuka K, Yasuda N, Shibusawa M, Kusano M. Anxiety, depression and quality of life in colorectal cancer patients. Int J Clin Oncol. 2005;10(6):411-417. https://doi.org/10.1007/s10147-005-0524-7

Auteurs

Evangelos C Karademas (EC)

Department of Psychology, University of Crete, Rethymnon, Greece.
Foundation for Research and Technology-Hellas, Heraklion, Greece.

Eugenia Mylona (E)

Foundation for Research and Technology-Hellas, Heraklion, Greece.

Ketti Mazzocco (K)

Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy.
Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology IRCCS, Milan, Italy.

Ruth Pat-Horenczyk (R)

School of Social Work and Social Welfare, Hebrew University of Jerusalem, Jerusalem, Israel.

Berta Sousa (B)

Breast Unit, Champalimaud Clinical Centre, Champalimaud Foundation, Lisboa, Portugal.

Albino J Oliveira-Maia (AJ)

Champalimaud Research and Clinical Centre, Champalimaud Foundation, Lisboa, Portugal.
NOVA Medical School, Faculdade de Ciências Médicas, NMS, FCM, Universidade NOVA de Lisboa, Lisboa, Portugal.

Jose Oliveira (J)

Champalimaud Research and Clinical Centre, Champalimaud Foundation, Lisboa, Portugal.
NOVA Medical School, Faculdade de Ciências Médicas, NMS, FCM, Universidade NOVA de Lisboa, Lisboa, Portugal.

Ilan Roziner (I)

Department of Communication Disorders, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Georgios Stamatakos (G)

Institute of Communication and Computer Systems, School of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece.

Fatima Cardoso (F)

Breast Unit, Champalimaud Clinical Centre, Champalimaud Foundation, Lisboa, Portugal.

Haridimos Kondylakis (H)

Foundation for Research and Technology-Hellas, Heraklion, Greece.

Eleni Kolokotroni (E)

Institute of Communication and Computer Systems, School of Electrical and Computer Engineering, National Technical University of Athens, Athens, Greece.

Konstantina Kourou (K)

Foundation for Research and Technology-Hellas, Heraklion, Greece.

Raquel Lemos (R)

Champalimaud Research and Clinical Centre, Champalimaud Foundation, Lisboa, Portugal.
ISPA-Instituto Universitário de Ciências Psicológicas, Sociais e da Vida, Lisboa, Portugal.

Isabel Manica (I)

Champalimaud Research and Clinical Centre, Champalimaud Foundation, Lisboa, Portugal.

George Manikis (G)

Foundation for Research and Technology-Hellas, Heraklion, Greece.

Chiara Marzorati (C)

Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology IRCCS, Milan, Italy.

Johanna Mattson (J)

Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
University of Helsinki, Helsinki, Finland.

Luzia Travado (L)

Champalimaud Research and Clinical Centre, Champalimaud Foundation, Lisboa, Portugal.

Chariklia Tziraki-Segal (C)

Hebrew University of Jerusalem Center for Sustainability, Jerusalem, Israel.

Dimitris Fotiadis (D)

Foundation for Research and Technology-Hellas, Heraklion, Greece.
Unit of Medical Technology and Intelligent Information Systems, Department of Materials Science and Engineering, University of Ioannina, Ioannina, Greece.

Paula Poikonen-Saksela (P)

Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.
University of Helsinki, Helsinki, Finland.

Panagiotis Simos (P)

Foundation for Research and Technology-Hellas, Heraklion, Greece.
Medical School, University of Crete, Rethymnon, Greece.

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