AI interprets the Central Dogma and Genetic Code.

Central Dogma ChatGPT Sequence Hypothesis artificial intelligence large language models natural language processing

Journal

Trends in biochemical sciences
ISSN: 0968-0004
Titre abrégé: Trends Biochem Sci
Pays: England
ID NLM: 7610674

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 19 06 2023
revised: 01 09 2023
accepted: 13 09 2023
medline: 13 11 2023
pubmed: 14 10 2023
entrez: 13 10 2023
Statut: ppublish

Résumé

Generative artificial intelligence (AI) is a burgeoning field with widespread applications, including in science. Here, we explore two paradigms that provide insight into the capabilities and limitations of Chat Generative Pre-trained Transformer (ChatGPT): its ability to (i) define a core biological concept (the Central Dogma of molecular biology); and (ii) interpret the genetic code.

Identifiants

pubmed: 37833131
pii: S0968-0004(23)00230-X
doi: 10.1016/j.tibs.2023.09.004
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1014-1018

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests No interests are declared.

Auteurs

Alexander M Ille (AM)

School of Graduate Studies, Rutgers University, Newark, NJ, USA. Electronic address: mai86@gsbs.rutgers.edu.

Michael B Mathews (MB)

School of Graduate Studies, Rutgers University, Newark, NJ, USA; Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA. Electronic address: mathews@njms.rutgers.edu.

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Classifications MeSH