Higher Infectivity of the Human Immunodeficiency Virus in Sensitive Cells with a Modification of the CCR5 Gene.
CCR5
CXCR4
MT-4 cells
human immunodeficiency virus type 1 (HIV-1)
Journal
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections
ISSN: 1608-3105
Titre abrégé: Dokl Biol Sci
Pays: United States
ID NLM: 7505459
Informations de publication
Date de publication:
Aug 2023
Aug 2023
Historique:
received:
03
02
2023
accepted:
10
03
2023
revised:
07
03
2023
medline:
1
11
2023
pubmed:
14
10
2023
entrez:
13
10
2023
Statut:
ppublish
Résumé
As a natural mutation of the human ccr5 gene has been shown to confer resistance to human immunodeficiency virus type 1 (HIV-1) infection, a new avenue has opened in the development of alternative treatment approaches through genome editing. One of the two chemokine co-receptors of the plasma membrane is utilized by HIV-1 to infect CD4
Identifiants
pubmed: 37833581
doi: 10.1134/S0012496623700412
pii: 10.1134/S0012496623700412
doi:
Substances chimiques
CCR5 protein, human
0
Receptors, CCR5
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
251-254Informations de copyright
© 2023. Pleiades Publishing, Ltd.
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