Design, Synthesis, and Potent Anticancer Activity of Novel Indole-Based Bcl-2 Inhibitors.
Bcl-2
anti-apoptotic protein
cancer drug discovery
indole
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
28 Sep 2023
28 Sep 2023
Historique:
received:
26
07
2023
revised:
16
08
2023
accepted:
20
08
2023
medline:
2
11
2023
pubmed:
14
10
2023
entrez:
14
10
2023
Statut:
epublish
Résumé
The Bcl-2 family plays a crucial role in regulating cell apoptosis, making it an attractive target for cancer therapy. In this study, a series of indole-based compounds,
Identifiants
pubmed: 37834104
pii: ijms241914656
doi: 10.3390/ijms241914656
pmc: PMC10572575
pii:
doi:
Substances chimiques
Antineoplastic Agents
0
Proto-Oncogene Proteins c-bcl-2
0
Indoles
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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