Consequences of Disturbing Manganese Homeostasis.
exposure to manganese
manganese
manganese neurotoxicity
manganese toxicity
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
06 Oct 2023
06 Oct 2023
Historique:
received:
11
09
2023
revised:
01
10
2023
accepted:
04
10
2023
medline:
23
10
2023
pubmed:
14
10
2023
entrez:
14
10
2023
Statut:
epublish
Résumé
Manganese (Mn) is an essential trace element with unique functions in the body; it acts as a cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant enzyme systems, neurotransmitter production, and the regulation of reproductive hormones. However, overexposure to Mn is toxic, particularly to the central nervous system (CNS) due to it causing the progressive destruction of nerve cells. Exposure to manganese is widespread and occurs by inhalation, ingestion, or dermal contact. Associations have been observed between Mn accumulation and neurodegenerative diseases such as manganism, Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis. People with genetic diseases associated with a mutation in the gene associated with impaired Mn excretion, kidney disease, iron deficiency, or a vegetarian diet are at particular risk of excessive exposure to Mn. This review has collected data on the current knowledge of the source of Mn exposure, the experimental data supporting the dispersive accumulation of Mn in the brain, the controversies surrounding the reference values of biomarkers related to Mn status in different matrices, and the competitiveness of Mn with other metals, such as iron (Fe), magnesium (Mg), zinc (Zn), copper (Cu), lead (Pb), calcium (Ca). The disturbed homeostasis of Mn in the body has been connected with susceptibility to neurodegenerative diseases, fertility, and infectious diseases. The current evidence on the involvement of Mn in metabolic diseases, such as type 2 diabetes mellitus/insulin resistance, osteoporosis, obesity, atherosclerosis, and non-alcoholic fatty liver disease, was collected and discussed.
Identifiants
pubmed: 37834407
pii: ijms241914959
doi: 10.3390/ijms241914959
pmc: PMC10573482
pii:
doi:
Substances chimiques
Manganese
42Z2K6ZL8P
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Environ Res. 1997;73(1-2):92-100
pubmed: 9311535
Int J Mol Sci. 2021 Aug 25;22(17):
pubmed: 34502091
Biochim Biophys Acta. 2010 Jan;1802(1):52-61
pubmed: 19682570
Brain Res Brain Res Rev. 2003 Jan;41(1):79-87
pubmed: 12505649
Mol Biol Cell. 2009 Jun;20(12):2810-9
pubmed: 19369420
J Trace Elem Med Biol. 2002;16(1):9-13
pubmed: 11878754
Biometals. 2003 Mar;16(1):41-54
pubmed: 12572663
Clin Chem Lab Med. 2013 Apr;51(4):839-49
pubmed: 23314559
Physiol Rev. 2004 Oct;84(4):1155-228
pubmed: 15383650
Toxicol Lett. 2013 Apr 26;218(3):299-307
pubmed: 23296100
Adv Neurobiol. 2017;18:113-142
pubmed: 28889265
Curr Environ Health Rep. 2015 Sep;2(3):315-28
pubmed: 26231508
Met Ions Biol Syst. 2000;37:89-121
pubmed: 10693132
J Neurochem. 2010 Mar;112(5):1190-8
pubmed: 20002294
Environ Res. 2004 Jun;95(2):119-25
pubmed: 15147916
Environ Toxicol Pharmacol. 2015 Jul;40(1):18-21
pubmed: 26056973
Anim Reprod Sci. 2022 Mar;238:106924
pubmed: 35121412
Biol Trace Elem Res. 2015 May;165(1):1-9
pubmed: 25578336
Breast Cancer Res. 2004;6(6):R647-55
pubmed: 15535847
Acta Neurol Scand Suppl. 1984;100:89-93
pubmed: 6592933
Neurotoxicology. 2012 Jan;33(1):91-7
pubmed: 22182530
J Trace Elem Med Biol. 2011 Jan;25(1):19-26
pubmed: 21242073
Ann Dermatol Venereol. 1982;109(8):667-78
pubmed: 7187192
PLoS Pathog. 2011 Sep;7(9):e1002261
pubmed: 21980287
J Am Chem Soc. 2006 Aug 2;128(30):9893-901
pubmed: 16866548
Biol Trace Elem Res. 2017 Feb;175(2):278-286
pubmed: 27334435
Int J Mol Sci. 2021 Oct 31;22(21):
pubmed: 34769276
Toxicol Sci. 2015 Aug;146(2):204-12
pubmed: 26220508
J Trace Elem Med Biol. 2015 Jan;29:123-9
pubmed: 24916793
Toxics. 2021 Jun 17;9(6):
pubmed: 34204190
Am J Clin Nutr. 2015 Dec;102(6):1482-9
pubmed: 26561627
J Neuroinflammation. 2018 Nov 21;15(1):324
pubmed: 30463564
J Bacteriol. 2011 Oct;193(19):5073-80
pubmed: 21784944
ACS Appl Mater Interfaces. 2015 Mar 11;7(9):5373-83
pubmed: 25685956
Cochrane Database Syst Rev. 2010 Dec 08;(12):CD005978
pubmed: 21154362
Neurology. 2019 Apr 2;92(14):e1580-e1588
pubmed: 30842294
Cureus. 2021 Mar 30;13(3):e14188
pubmed: 33936898
Neuroimage. 2015 Oct 15;120:36-42
pubmed: 26142275
Andrologia. 2014 Apr;46(3):246-53
pubmed: 23374134
Int J Environ Res Public Health. 2022 Sep 04;19(17):
pubmed: 36078782
Int J Mol Sci. 2021 Oct 09;22(20):
pubmed: 34681565
Biol Trace Elem Res. 1989 Dec;22(3):251-6
pubmed: 2484410
Nutrients. 2023 Jun 19;15(12):
pubmed: 37375704
Neurology. 2005 Jan 25;64(2):230-5
pubmed: 15668418
FASEB J. 2007 Jan;21(1):223-30
pubmed: 17116743
Res Autism Spectr Disord. 2015 Oct 1;18:73-82
pubmed: 26309447
Nature. 2001 Dec 13;414(6865):782-7
pubmed: 11742409
Neurotoxicology. 2011 Mar;32(2):171-9
pubmed: 21192973
Brain Res Mol Brain Res. 2004 Mar 30;122(2):167-79
pubmed: 15010209
J Autism Dev Disord. 2012 Jun;42(6):929-36
pubmed: 21735299
Polymers (Basel). 2020 Nov 13;12(11):
pubmed: 33202968
Redox Biol. 2018 May;15:490-503
pubmed: 29413961
J Toxicol Environ Health A. 2010;73(13-14):878-87
pubmed: 20563921
Arch Public Health. 2023 Mar 15;81(1):40
pubmed: 36918930
Environ Res. 2013 May;123:52-7
pubmed: 23578827
Microbiology (Reading). 2012 Mar;158(Pt 3):804-815
pubmed: 22222497
Neurology. 1996 Feb;46(2):492-8
pubmed: 8614520
Toxicol Sci. 2008 Feb;101(2):310-20
pubmed: 17977900
Nature. 2000 Apr 13;404(6779):787-90
pubmed: 10783895
Biometals. 2013 Dec;26(6):941-53
pubmed: 23996061
Toxicology. 2003 May 3;187(2-3):139-48
pubmed: 12699903
Arch Environ Occup Health. 2014;69(1):46-54
pubmed: 23930796
Int J Hyg Environ Health. 2012 Feb;215(2):102-8
pubmed: 22178406
Adv Neurobiol. 2020;24:193-206
pubmed: 32006361
Neurotoxicology. 2006 Mar;27(2):229-36
pubmed: 16325911
Biol Reprod. 1998 Sep;59(3):599-605
pubmed: 9716559
Nat Rev Microbiol. 2012 Jul 16;10(8):525-37
pubmed: 22796883
Arch Toxicol. 2013 Jul;87(7):1231-44
pubmed: 23385959
Biol Trace Elem Res. 2023 Jun;201(6):2701-2710
pubmed: 35896886
Aquat Toxicol. 2015 Jan;158:192-201
pubmed: 25481785
Environ Res. 2012 Oct;118:65-71
pubmed: 22925625
Metallomics. 2016 Jun 1;8(6):628-32
pubmed: 26962965
J Trace Elem Med Biol. 2019 Dec;56:146-155
pubmed: 31470248
Exp Eye Res. 2017 Jan;154:47-52
pubmed: 27984016
Environ Health. 2014 Oct 24;13:87
pubmed: 25342305
Environ Monit Assess. 2015 Nov;187(11):677
pubmed: 26446131
Toxicol Sci. 2016 Apr;150(2):292-300
pubmed: 26721301
Diabetes Care. 1991 Nov;14(11):1050-6
pubmed: 1797486
J Trop Pediatr. 2011 Dec;57(6):457-60
pubmed: 21300623
Acta Neuropathol Commun. 2013 May 09;1:11
pubmed: 24252509
Environ Health. 2016 Aug 30;15(1):91
pubmed: 27576472
Front Aging Neurosci. 2020 Nov 10;12:556008
pubmed: 33244298
Front Pediatr. 2023 Jul 04;11:1169733
pubmed: 37469682
Environ Health Perspect. 2017 May 26;125(5):057003
pubmed: 28564632
J Hematother Stem Cell Res. 2001 Feb;10(1):27-42
pubmed: 11276357
Scand J Clin Lab Invest. 2014 Mar;74(2):143-8
pubmed: 24329009
Chemosphere. 2007 Nov;70(1):155-64
pubmed: 17707880
Biol Trace Elem Res. 2001 Mar;79(3):205-19
pubmed: 11354346
Biochem Med (Zagreb). 2016;26(1):5-16
pubmed: 26981015
J Inherit Metab Dis. 2010 Dec;33 Suppl 3:S503-6
pubmed: 21229317
J Neurosci Res. 2006 Jun;83(8):1601-10
pubmed: 16568477
Environ Health Perspect. 2014 Dec;122(12):1343-50
pubmed: 25260096
Biochem J. 2006 Sep 15;398(3):539-46
pubmed: 16737442
Molecules. 2020 Dec 12;25(24):
pubmed: 33322668
Environ Health Perspect. 2010 Aug;118(8):1071-80
pubmed: 20403794
J Nutr. 1989 Oct;119(10):1461-4
pubmed: 2585137
J Toxicol Environ Health A. 2007 Sep;70(18):1515-26
pubmed: 17710612
Hum Genomics. 2019 Sep 14;13(Suppl 1):51
pubmed: 31521203
Neurotoxicology. 2012 Oct;33(5):1356-61
pubmed: 22975422
Biol Trace Elem Res. 1998 Winter;66(1-3):185-91
pubmed: 10050919
Int J Mol Sci. 2021 Aug 07;22(16):
pubmed: 34445217
Neurotoxicology. 1981 Jan;2(1):65-73
pubmed: 15622725
Occup Environ Med. 2012 Jun;69(6):437-43
pubmed: 22447645
Neurochem Res. 2011 Aug;36(8):1546-57
pubmed: 21533646
Oxid Med Cell Longev. 2013;2013:316523
pubmed: 23983897
J Trace Elem Med Biol. 2019 Dec;56:124-130
pubmed: 31466044
PLoS Genet. 2010 Aug 26;6(8):
pubmed: 20865164
Met Ions Life Sci. 2013;13:199-227
pubmed: 24470093
Brain Res. 2011 Mar 25;1382:282-90
pubmed: 21262206
Nutrients. 2019 Jun 28;11(7):
pubmed: 31261654
Chem Rev. 2009 Oct;109(10):4862-84
pubmed: 19534496
Exp Neurol. 1993 Mar;120(1):89-94
pubmed: 8477830
Vet J. 2003 Sep;166(2):125-39
pubmed: 12902178
Int J Mol Sci. 2021 Apr 28;22(9):
pubmed: 33925013
Neurotoxicology. 2003 Aug;24(4-5):667-74
pubmed: 12900080
Clin Chem. 1979 Nov;25(11):1915-8
pubmed: 498501
J Child Adolesc Psychopharmacol. 2010 Apr;20(2):113-8
pubmed: 20415606
Nutrients. 2017 Feb 03;9(2):
pubmed: 28165362
J Biol Chem. 2000 Jun 30;275(26):19906-12
pubmed: 10747949
Molecules. 2022 Mar 15;27(6):
pubmed: 35335273
Toxicol Sci. 2007 Jul;98(1):198-205
pubmed: 17468184
Mol Neurobiol. 2020 May;57(5):2314-2332
pubmed: 32026227
Acta Derm Venereol. 2004;84(3):191-4
pubmed: 15202834
Am J Hum Genet. 2015 Dec 3;97(6):886-93
pubmed: 26637978
J Biol Chem. 2012 May 25;287(22):18717-29
pubmed: 22493290
Ann Nutr Metab. 2013;63(1-2):168-73
pubmed: 24021752
Toxicol Sci. 2011 Jul;122(1):121-33
pubmed: 21512103
Proc Soc Exp Biol Med. 1998 Oct;219(1):41-7
pubmed: 9751221
J Trace Elem Med Biol. 2014 Apr;28(2):106-116
pubmed: 24200516
J Neurochem. 2019 Jul;150(2):188-201
pubmed: 30720866
Mol Cell Biochem. 2017 May;429(1-2):1-10
pubmed: 28083716
Neurotoxicology. 2012 Jun;33(3):401-5
pubmed: 22542452
Toxicol Sci. 2010 Sep;117(1):169-79
pubmed: 20547568
BMC Public Health. 2012 Oct 29;12:919
pubmed: 23107312
Biol Trace Elem Res. 2014 Jun;159(1-3):445-50
pubmed: 24867776
Environ Health Perspect. 2011 Feb;119(2):219-24
pubmed: 20876035
Metallomics. 2011 Jan;3(1):38-41
pubmed: 21275153
Arch Neurol. 1999 May;56(5):569-74
pubmed: 10328252
J Am Coll Cardiol. 2007 Feb 13;49(6):631-42
pubmed: 17291928
Metallomics. 2020 Jul 22;12(7):1118-1130
pubmed: 32421118
Arch Biochem Biophys. 2015 Jul;577-578:49-59
pubmed: 25935364
PLoS One. 2013;8(3):e58792
pubmed: 23516557
Osteoarthritis Cartilage. 2000 Sep;8(5):343-50
pubmed: 10966840
Early Hum Dev. 1991 Oct;26(3):223-6
pubmed: 1773749
Curr Probl Pediatr Adolesc Health Care. 2014 Nov;44(10):277-318
pubmed: 25199954
Environ Res. 2015 Oct;142:688-95
pubmed: 26381693
Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1769-E1778
pubmed: 29437953
J Anim Sci. 2021 Aug 1;99(8):
pubmed: 33982089
Mol Hum Reprod. 2000 Jan;6(1):19-25
pubmed: 10611256
Biol Trace Elem Res. 2013 Nov;155(2):184-9
pubmed: 23955423
Toxicol Sci. 2013 Dec;136(2):373-81
pubmed: 23997110
Science. 2002 Jul 19;297(5580):353-6
pubmed: 12130773
Am J Ind Med. 2007 Nov;50(11):801-11
pubmed: 17924418
Sci Total Environ. 2013 Jun 1;454-455:562-77
pubmed: 23570911
Ann N Y Acad Sci. 2010 Nov;1212:78-96
pubmed: 21070247
Neurotoxicol Teratol. 2014 Jan-Feb;41:71-9
pubmed: 24370548
Chemosphere. 2015 Jun;128:70-8
pubmed: 25655821
Am J Hum Genet. 2012 Mar 9;90(3):467-77
pubmed: 22341971
J Trace Elem Med Biol. 2006;20(4):253-62
pubmed: 17098585
Antiviral Res. 2014 Nov;111:136-42
pubmed: 25260898
Clin Chem. 1980 Mar;26(3):531-2
pubmed: 7363482
Neurotoxicology. 2018 Jul;67:112-120
pubmed: 29778792
Aging (Milano). 2000 Dec;12(6):470-7
pubmed: 11211958
Am J Clin Nutr. 1994 Dec;60(6):949-55
pubmed: 7985639
J Neurochem. 2008 Jun;105(5):1948-59
pubmed: 18284614
Poult Sci. 2005 Jan;84(1):100-5
pubmed: 15685948
Environ Health Perspect. 2011 Jan;119(1):138-43
pubmed: 20855239
J Nutr. 1990 Sep;120(9):1075-9
pubmed: 2204694
Diagnostics (Basel). 2022 Nov 08;12(11):
pubmed: 36359577
Environ Int. 2021 Jul;152:106468
pubmed: 33765546
J Inherit Metab Dis. 2008 Apr;31(2):151-63
pubmed: 18392750
Neurotoxicology. 2006 Jan;27(1):125-30
pubmed: 16140386
J Clin Endocrinol Metab. 2010 Nov;95(11):E291-9
pubmed: 20685861
FASEB J. 2019 Feb;33(2):2228-2240
pubmed: 30247984
Forensic Sci Int. 2005 Oct 4;153(1):39-44
pubmed: 15979835
Neurochem Int. 2006 May-Jun;48(6-7):426-33
pubmed: 16513220
J Appl Toxicol. 2012 May;32(5):310-7
pubmed: 22120544
Neurotoxicology. 2018 Jan;64:219-229
pubmed: 28651968
J Trace Elem Med Biol. 2011 Jan;25 Suppl 1:S3-10
pubmed: 21167697
NMR Biomed. 2003 Apr;16(2):82-95
pubmed: 12730949
Metallomics. 2012 Jul;4(7):700-8
pubmed: 22534978
Oxid Med Cell Longev. 2009 Jul-Aug;2(3):152-9
pubmed: 20592770
Int J Mol Sci. 2022 Mar 11;23(6):
pubmed: 35328471
Environ Int. 2016 Sep;94:177-188
pubmed: 27258659
J Nutr. 2007 Dec;137(12):2809-13
pubmed: 18029504
Int J Mol Sci. 2021 Nov 03;22(21):
pubmed: 34769364
Neurosci Biobehav Rev. 2021 Oct;129:117-132
pubmed: 34339708
J Trace Elem Med Biol. 1997 Jun;11(2):92-8
pubmed: 9285889
FEBS Lett. 2001 Dec 7;509(2):309-16
pubmed: 11741608
Diabetes Res Clin Pract. 2011 Mar;91(3):333-41
pubmed: 21211861
Int J Environ Res Public Health. 2018 Jun 10;15(6):
pubmed: 29890770
J Bacteriol. 2010 Sep;192(17):4489-97
pubmed: 20601473
Int J Environ Res Public Health. 2015 Apr 10;12(4):3944-61
pubmed: 25867198
Am J Clin Nutr. 1992 Mar;55(3):747-52
pubmed: 1550052
Nat Commun. 2016 May 27;7:11601
pubmed: 27231142
Indian J Clin Biochem. 2022 Oct;37(4):487-493
pubmed: 36262780
Nutrients. 2016 Aug 13;8(8):
pubmed: 27529280
Int J Appl Radiat Isot. 1964 Apr;15:175-90
pubmed: 14138346
Int J Environ Res Public Health. 2019 Sep 22;16(19):
pubmed: 31546716
Arch Gerontol Geriatr. 2013 Mar-Apr;56(2):389-94
pubmed: 23245729
J Nutr. 1992 Jun;122(6):1300-8
pubmed: 1588448
J Neurosci Methods. 2011 Nov 15;202(2):182-91
pubmed: 21740928
Public Health Nutr. 2013 Sep;16(9):1677-83
pubmed: 23534837
Indian J Med Res. 2008 Oct;128(4):484-500
pubmed: 19106442
Front Genet. 2017 Nov 17;8:177
pubmed: 29204154
Climacteric. 2015 Jun;18(3):379-88
pubmed: 25236970
Eukaryot Cell. 2005 Jul;4(7):1159-65
pubmed: 16002642
Environ Health. 2016 Mar 12;15:44
pubmed: 26968381
Sci Signal. 2019 Jan 08;12(563):
pubmed: 30622196
Front Neurosci. 2019 Jun 26;13:654
pubmed: 31293375
Neurotoxicology. 1999 Apr-Jun;20(2-3):343-53
pubmed: 10385895
Brain Res Rev. 2007 Feb;53(2):332-6
pubmed: 17166592
Toxicol Sci. 2008 May;103(1):116-24
pubmed: 18234737
Metab Brain Dis. 2016 Oct;31(5):1047-54
pubmed: 27250967
J Biol Chem. 2001 Nov 23;276(47):44284-96
pubmed: 11553618
Toxicol Appl Pharmacol. 2009 Oct 15;240(2):219-25
pubmed: 19607852
Parkinsons Dis. 2011 Feb 17;2011:865319
pubmed: 21403909
Clin Cases Miner Bone Metab. 2016 Sep-Dec;13(3):181-185
pubmed: 28228778
Br J Dermatol. 1999 Jan;140(1):26-34
pubmed: 10215764
Int J Hyg Environ Health. 2013 Mar;216(2):170-4
pubmed: 22494935
Metallomics. 2014 Apr;6(4):921-31
pubmed: 24599255
Annu Rev Nutr. 2015;35:71-108
pubmed: 25974698
J Trace Elem Med Biol. 2015 Oct;32:145-54
pubmed: 26302922
Sci Rep. 2017 Feb 03;7:41804
pubmed: 28155922
PLoS Med. 2014 May 27;11(5):e1001651
pubmed: 24866475
Neurotoxicology. 2013 Mar;35:121-8
pubmed: 23313730
Mol Med Rep. 2017 May;15(5):3340-3349
pubmed: 28339021
Hum Mol Genet. 2000 Nov 22;9(19):2799-809
pubmed: 11092756
Breast Cancer Res Treat. 2008 Mar;108(2):203-15
pubmed: 17473980
Biofactors. 1999;10(1):15-24
pubmed: 10475586
Environ Health Perspect. 2006 Aug;114(8):1172-8
pubmed: 16882521
Mol Aspects Med. 2005 Aug-Oct;26(4-5):353-62
pubmed: 16099026
Neurotoxicology. 2018 Jan;64:60-67
pubmed: 28803850
J Nutr Biochem. 2004 Jun;15(6):335-41
pubmed: 15157939
Metallomics. 2017 Aug 16;9(8):1028-1046
pubmed: 28620665
Neurotoxicology. 1984 Spring;5(1):67-76
pubmed: 6144084
Biochem Biophys Res Commun. 2013 Mar 1;432(1):1-4
pubmed: 23357421
Biol Trace Elem Res. 2013 Dec;156(1-3):79-90
pubmed: 24222606
Nutr Hosp. 2011 Sep-Oct;26(5):965-70
pubmed: 22072339
J Neurosci. 2007 Oct 24;27(43):11758-68
pubmed: 17959817
J Biol Chem. 2015 Sep 25;290(39):23725-37
pubmed: 26269591
Sci Total Environ. 2012 Jun 15;427-428:19-25
pubmed: 22551936
Epilepsia. 1993 May-Jun;34(3):441-6
pubmed: 8099325
J Med Chem. 2010 May 27;53(10):4266-76
pubmed: 20441173
Environ Health Perspect. 2011 Oct;119(10):1501-6
pubmed: 21493178
Vascul Pharmacol. 2016 Sep;84:67-73
pubmed: 27401963
Environ Sci Technol. 2014 Dec 16;48(24):14695-702
pubmed: 25390650
Environ Sci Technol. 2011 May 1;45(9):4096-101
pubmed: 21438595
J Inorg Biochem. 1981 Jun;14(3):253-60
pubmed: 6114986
Curr Environ Health Rep. 2017 Jun;4(2):223-228
pubmed: 28417441
Mol Med Rep. 2012 Oct;6(4):797-804
pubmed: 22825700
Toxicol Sci. 2015 Apr;144(2):318-27
pubmed: 25601986
Front Mol Neurosci. 2017 Oct 24;10:339
pubmed: 29114205
Biochim Biophys Acta. 2006 Jul;1763(7):747-58
pubmed: 16828895
Int J Hyg Environ Health. 2010 Jul;213(4):252-8
pubmed: 20418157
J Clin Hypertens (Greenwich). 2022 Jul;24(7):918-927
pubmed: 35748116
Int J Mol Sci. 2021 Nov 05;22(21):
pubmed: 34769404
Neurotoxicology. 2010 Sep;31(5):572-4
pubmed: 20188756
Saf Health Work. 2014 Sep;5(3):113-7
pubmed: 25379323
Foods. 2020 Oct 16;9(10):
pubmed: 33081306
Brain Res Bull. 1994;33(3):345-9
pubmed: 8293318
Iran J Med Sci. 2016 Nov;41(6):518-524
pubmed: 27853332
J Neurochem. 2016 May;137(3):331-59
pubmed: 26852372
Handb Clin Neurol. 2015;131:169-89
pubmed: 26563789
Epidemiology. 2009 May;20(3):367-73
pubmed: 19289966
J Biol Chem. 2020 May 8;295(19):6312-6329
pubmed: 32188696
Neurotoxicol Teratol. 2016 Jul-Aug;56:55-67
pubmed: 27302314
J Trace Elem Med Biol. 2014 Jan;28(1):45-9
pubmed: 24210171
Int J Mol Sci. 2021 Aug 31;22(17):
pubmed: 34502369
Neurochem Res. 2012 Mar;37(3):469-79
pubmed: 22033861
Neurotoxicology. 2002 Oct;23(4-5):635-43
pubmed: 12428735
Environ Res. 2013 Feb;121:39-44
pubmed: 23141434
J Dermatolog Treat. 2009;20(2):90-3
pubmed: 19296347
Int J Mol Sci. 2021 Jul 22;22(15):
pubmed: 34360586
Future Neurol. 2012 Mar;7(2):145-153
pubmed: 22563296
Food Addit Contam. 2005 Jul;22(7):624-41
pubmed: 16019838
Curr Environ Health Rep. 2015 Sep;2(3):284-94
pubmed: 26231505
Int J Food Sci Nutr. 2009 Nov;60(7):590-600
pubmed: 19817638
Environ Res. 2011 Jan;111(1):156-63
pubmed: 20943219
Nutr Clin Pract. 2012 Aug;27(4):440-91
pubmed: 22730042
Am J Clin Nutr. 1995 Mar;61(3 Suppl):621S-624S
pubmed: 7879727
Adv Neurobiol. 2017;18:159-181
pubmed: 28889267
Int J Mol Sci. 2022 Feb 14;23(4):
pubmed: 35216231
J Med Case Rep. 2012 Feb 07;6:52
pubmed: 22313512
Environ Health Perspect. 2016 Dec;124(12):1876-1881
pubmed: 27258818
J Biol Chem. 2011 Aug 26;286(34):29654-62
pubmed: 21724849
J Trace Elem Med Biol. 2021 Sep;67:126772
pubmed: 34000573
Neurotoxicology. 2008 Nov;29(6):1044-53
pubmed: 18771689
Neurotoxicology. 2006 May;27(3):311-4
pubmed: 16460806
Medicine (Baltimore). 2018 Jun;97(22):e10775
pubmed: 29851783
Neurosci Lett. 2001 Dec 4;316(1):5-8
pubmed: 11720765
World Health Organ Tech Rep Ser. 1980;647:1-116
pubmed: 6775420
Toxicol Lett. 2014 Dec 1;231(2):179-93
pubmed: 25151427
Metallomics. 2015 May;7(5):748-55
pubmed: 25695229
Int J Environ Res Public Health. 2022 Apr 06;19(7):
pubmed: 35410100
Environ Health Perspect. 2015 Oct;123(10):1066-71
pubmed: 25902278
Int J Diabetes Dev Ctries. 2009 Jan;29(1):35-40
pubmed: 20062562
Cell Metab. 2011 Dec 7;14(6):724-38
pubmed: 22152301
Talanta. 2010 Oct 15;82(5):1770-7
pubmed: 20875575
Toxicol Sci. 2015 Feb;143(2):482-98
pubmed: 25575534
Toxicol In Vitro. 2008 Feb;22(1):18-27
pubmed: 17845838
Free Radic Res. 2001 Apr;34(4):325-36
pubmed: 11328670
Ecotoxicol Environ Saf. 2020 Oct 15;203:110975
pubmed: 32678756
Environ Health Perspect. 2006 Jan;114(1):124-9
pubmed: 16393669
Nat Commun. 2022 Oct 13;13(1):6061
pubmed: 36229432
Neurology. 1969 Oct;19(10):1000-6
pubmed: 5387706
J Toxicol Environ Health. 1982 Apr;9(4):677-87
pubmed: 7108982
Environ Int. 2015 Nov;84:39-54
pubmed: 26209874
Nutrients. 2017 Mar 03;9(3):
pubmed: 28273828
Exp Neurol. 1998 Jan;149(1):277-83
pubmed: 9454637
Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):858-63
pubmed: 21187401
Metallomics. 2011 Mar;3(3):267-70
pubmed: 21298161
Free Radic Biol Med. 2014 Dec;77:139-51
pubmed: 25224035
Nutr Res Pract. 2008 Spring;2(1):22-5
pubmed: 20126361
J Alzheimers Dis. 2014;42(3):865-78
pubmed: 24961945
Neurotoxicology. 2016 Sep;56:262-268
pubmed: 27293182
Ann N Y Acad Sci. 2004 Mar;1012:209-23
pubmed: 15105268
Br J Nutr. 2012 Jul;108(2):267-76
pubmed: 22172096
J Neurochem. 1981 Apr;36(4):1443-8
pubmed: 7264641
Toxicol Sci. 2005 Mar;84(1):139-48
pubmed: 15601679
Am J Clin Nutr. 1999 Jul;70(1):37-43
pubmed: 10393136
Neurology. 1994 Sep;44(9):1583-6
pubmed: 7936278
Int J Mol Sci. 2021 Dec 11;22(24):
pubmed: 34948118
Mol Pharmacol. 2006 Jul;70(1):171-80
pubmed: 16638970
Ann Clin Biochem. 2012 Jul;49(Pt 4):341-51
pubmed: 22362086
Toxicol Res. 2015 Mar;31(1):17-23
pubmed: 25874029
J Neuroinflammation. 2017 May 5;14(1):99
pubmed: 28476157
Toxicol Sci. 2015 Feb;143(2):454-68
pubmed: 25416158
Int J Environ Res Public Health. 2015 Jul 06;12(7):7519-40
pubmed: 26154659
NMR Biomed. 2004 Dec;17(8):544-53
pubmed: 15617053
Indian J Pediatr. 2010 Jul;77(7):789-93
pubmed: 20589461
Int J Hyg Environ Health. 2007 May;210(3-4):495-9
pubmed: 17296328
Toxicol Sci. 2011 Aug;122(2):297-316
pubmed: 21622944
Chang Gung Med J. 2007 Sep-Oct;30(5):385-95
pubmed: 18062168
Cardiovasc Diabetol. 2013 Jan 09;12:9
pubmed: 23302150
Hypertens Res. 2023 Aug;46(8):1870-1879
pubmed: 37185603
Int J Dev Neurosci. 2011 Jun;29(4):365-75
pubmed: 21458557
Biol Trace Elem Res. 2005 Jul;106(1):1-28
pubmed: 16037607
Food Nutr Bull. 2009 Mar;30(1 Suppl):S41-59
pubmed: 19472601
Science. 2005 Jan 21;307(5708):384-7
pubmed: 15662004
Amino Acids. 2012 Jan;42(1):139-58
pubmed: 20454814
Eur J Clin Nutr. 2006 Jan;60(1):1-8
pubmed: 16118651
Neurotoxicology. 1984 Spring;5(1):37-47
pubmed: 6144083
Sci Rep. 2018 Feb 16;8(1):3163
pubmed: 29453449
Int J Mol Sci. 2020 May 06;21(9):
pubmed: 32384730
BMC Pharmacol Toxicol. 2013 Apr 18;14:23
pubmed: 23594835
Environ Res. 2013 Oct;126:9-16
pubmed: 23790803
J Trace Elem Med Biol. 2016 Dec;38:183-193
pubmed: 27085215
Epidemiology. 2007 Mar;18(2):270-3
pubmed: 17202870
Maturitas. 2021 Jan;143:127-131
pubmed: 33308618
J Nutr Biochem. 2005 Jan;16(1):44-9
pubmed: 15629240
Biology (Basel). 2020 May 21;9(5):
pubmed: 32455636
Curr Environ Health Rep. 2016 Dec;3(4):392-404
pubmed: 27722879
Brain Res. 2010 Nov 4;1359:201-7
pubmed: 20735995
Free Radic Biol Med. 2020 Nov 20;160:149-162
pubmed: 32745763
Int J Mol Sci. 2022 Dec 14;23(24):
pubmed: 36555531
PLoS One. 2014 Jan 24;9(1):e86866
pubmed: 24475187
Toxicol Sci. 2002 Feb;65(2):166-76
pubmed: 11812920
Res Autism Spectr Disord. 2014 Sep 1;8(9):1134-1145
pubmed: 25089152
Neurotoxicology. 2011 Mar;32(2):247-54
pubmed: 21182864
Environ Sci Technol. 2013 Feb 5;47(3):1629-37
pubmed: 23259818
J Neurochem. 2015 Aug;134(4):601-10
pubmed: 25982296
Neurotoxicology. 2012 Oct;33(5):1346-55
pubmed: 22975423
J Trace Elem Med Biol. 2016 Jan;33:114-9
pubmed: 26653752
Neurotoxicology. 2015 May;48:109-19
pubmed: 25732873
Biol Trace Elem Res. 2008 Apr;122(1):1-18
pubmed: 18193174
Heliyon. 2016 Jan 12;2(1):e00054
pubmed: 27441237
Toxicol Appl Pharmacol. 2007 Jun 1;221(2):131-47
pubmed: 17466353
Neurotoxicology. 2007 Sep;28(5):951-6
pubmed: 17576015
J Anal Toxicol. 2013 Sep;37(7):401-5
pubmed: 23794607
BMC Endocr Disord. 2014 Mar 08;14:24
pubmed: 24606630
Neurotoxicology. 2018 Mar;65:280-288
pubmed: 29183790
J Neurol Sci. 2002 Apr 15;196(1-2):45-52
pubmed: 11959156
Toxicol Sci. 2009 Dec;112(2):405-15
pubmed: 19812365
Neurotoxicology. 2005 Jan;26(1):107-11
pubmed: 15527878
J Neurocytol. 2001 Apr;30(4):353-60
pubmed: 11875282
J Hepatol. 2003 Dec;39(6):978-83
pubmed: 14642615
Int J Med Chem. 2011;2011:403039
pubmed: 25954517
Sci Rep. 2018 Jan 9;8(1):211
pubmed: 29317744
Fed Proc Transl Suppl. 1965 Mar-Apr;24:237-8
pubmed: 14304755
J Neurochem. 2010 Jan;112(1):227-37
pubmed: 19845833
Mol Autism. 2015 Oct 23;6:57
pubmed: 26500752
Metallomics. 2014 Apr;6(4):822-32
pubmed: 24549144
Br J Nutr. 2018 Jul;120(1):81-89
pubmed: 29673411
J Anal Toxicol. 2015 Nov-Dec;39(9):707-13
pubmed: 26265286
Oxid Med Cell Longev. 2018 Apr 5;2018:7580707
pubmed: 29849912
Neurotoxicology. 2014 Dec;45:301-8
pubmed: 24308913
Trends Microbiol. 2001 Aug;9(8):397-403
pubmed: 11514223
Front Immunol. 2013 Sep 17;4:278
pubmed: 24062745
Nat Commun. 2015 Feb 05;6:6053
pubmed: 25651975
J Cereb Blood Flow Metab. 2011 Dec;31(12):2324-33
pubmed: 21712832
Bioanalysis. 2014 Aug;6(17):2245-59
pubmed: 25383735
Sci Signal. 2019 Mar 12;12(572):
pubmed: 30862700
J Nutr. 2000 Nov;130(11):2821-30
pubmed: 11053527
Neurotoxicology. 2009 Jul;30(4):564-71
pubmed: 19635390
Lancet Neurol. 2014 Oct;13(10):1045-60
pubmed: 25231526
iScience. 2023 Jun 15;26(7):107136
pubmed: 37408687
Crit Rev Toxicol. 2005 Jan;35(1):1-32
pubmed: 15742901
Am J Physiol Gastrointest Liver Physiol. 2005 Dec;289(6):G981-6
pubmed: 16286504
Neurotoxicology. 2008 Jul;29(4):569-76
pubmed: 18565586
Talanta. 1973 Sep;20(9):835-42
pubmed: 18961353
Iran Biomed J. 2014;18(1):41-8
pubmed: 24375162
Nutrition. 1999 Oct;15(10):731-4
pubmed: 10501283
Brain Res. 2008 Mar 10;1198:160-70
pubmed: 18243167
J Nutr. 1987 Jan;117(1):133-43
pubmed: 3819860
Environ Res. 2006 Jan;100(1):100-14
pubmed: 16337847
Obesity (Silver Spring). 2014 Jan;22(1):178-87
pubmed: 23526686
Toxicol Sci. 2017 Oct 1;159(2):366-379
pubmed: 28962525
Poult Sci. 2014 Apr;93(4):959-69
pubmed: 24706974
Science. 2004 Dec 17;306(5704):2090-3
pubmed: 15514116
Neurochem Res. 2012 Mar;37(3):455-68
pubmed: 22083668
Environ Sci Pollut Res Int. 2018 Jun;25(18):17950-17956
pubmed: 29680891
Nature. 1997 Jul 31;388(6641):482-8
pubmed: 9242408
Toxicol Rev. 2006;25(3):147-54
pubmed: 17192121
Am J Hum Genet. 2012 Mar 9;90(3):457-66
pubmed: 22341972
Neuroscience. 2004;128(3):487-96
pubmed: 15381278
Neurochem Res. 2017 Feb;42(2):656-666
pubmed: 27900599
Biochim Biophys Acta. 1997 Sep 4;1328(2):90-8
pubmed: 9315607
Neurotoxicology. 2011 Oct;32(5):615-21
pubmed: 21871921
BMC Pharmacol Toxicol. 2016 Nov 4;17(1):57
pubmed: 27814772
Int J Mol Sci. 2022 Sep 15;23(18):
pubmed: 36142660
Parkinsonism Relat Disord. 2015 Jun;21(6):635-9
pubmed: 25903042
Am J Ind Med. 2007 Nov;50(11):841-52
pubmed: 17918212
Nutrients. 2022 Feb 16;14(4):
pubmed: 35215474
PLoS One. 2015 Jun 30;10(6):e0131815
pubmed: 26125595
Reprod Toxicol. 2006 Nov;22(4):580-5
pubmed: 16697554
Neurology. 1986 Dec;36(12):1584-7
pubmed: 3785672
J Biochem Mol Toxicol. 2017 Dec;31(12):
pubmed: 29205667
J Biol Chem. 1998 May 22;273(21):13080-8
pubmed: 9582346
J Clin Invest. 2017 Jun 1;127(6):2407-2417
pubmed: 28481222
Guang Pu Xue Yu Guang Pu Fen Xi. 2005 Jan;25(1):83-5
pubmed: 15852826
Int J Hyg Environ Health. 2012 Apr;215(3):411-7
pubmed: 22169700
Zdravookhr Beloruss. 1963 Apr;9:49-53
pubmed: 14064740
Neurotoxicology. 2011 Jan;32(1):1-8
pubmed: 20946915
J Inherit Metab Dis. 2017 Mar;40(2):261-269
pubmed: 27995398
Neurotoxicology. 2008 May;29(3):466-70
pubmed: 18400301
Neurobehav Toxicol Teratol. 1983 May-Jun;5(3):385-9
pubmed: 6410294
Sci Rep. 2015 Jan 26;5:8016
pubmed: 25619900
Cell Metab. 2005 Mar;1(3):191-200
pubmed: 16054062
J Occup Environ Med. 2011 May;53(5):506-10
pubmed: 21494156
Res Autism Spectr Disord. 2020 Nov;79:
pubmed: 33193808
Mol Cell. 2000 Feb;5(2):299-309
pubmed: 10882071
Neurochem Int. 2018 Jul;117:91-113
pubmed: 29550604
Epidemiology. 2010 Jul;21(4):433-9
pubmed: 20549838
Toxicol Appl Pharmacol. 2010 Nov 15;249(1):65-75
pubmed: 20800605
Environ Res. 2016 May;147:32-43
pubmed: 26844420
Cell Mol Biol Lett. 2015 Dec;20(4):685-97
pubmed: 26336112
Med Sci Monit. 2006 Jan;12(1):BR8-14
pubmed: 16369462
Biochem Biophys Res Commun. 2018 Mar 25;498(1):171-177
pubmed: 29408508
Lancet. 2007 Jan 20;369(9557):218-28
pubmed: 17240289
J Matern Fetal Neonatal Med. 2016;29(2):274-8
pubmed: 25655527
Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2331-6
pubmed: 16873728
Ann Neurol. 2014 Apr;75(4):608-12
pubmed: 24599576
Biochim Biophys Acta. 2013 Jan;1834(1):197-204
pubmed: 22999980
ACS Nano. 2019 Apr 23;13(4):4302-4311
pubmed: 30925040
Cells. 2022 Jul 15;11(14):
pubmed: 35883654
Br J Nutr. 2016 Sep;116(5):853-63
pubmed: 27385039
Diab Vasc Dis Res. 2018 Jul;15(4):336-339
pubmed: 29383971
Int J Mol Sci. 2021 Oct 27;22(21):
pubmed: 34769040
Pharmacol Res. 2021 Apr;166:105437
pubmed: 33493659
Brain Res Bull. 2021 Sep;174:268-280
pubmed: 34077795
Mol Cell Biol. 2014 Apr;34(7):1280-9
pubmed: 24469401
Toxicol Sci. 2010 Jun;115(2):535-46
pubmed: 20176619
Neurotoxicology. 2018 Jan;64:30-42
pubmed: 28873337
J Alzheimers Dis. 1999 Oct;1(3):139-145
pubmed: 12213999
Int Rev Neurobiol. 2013;110:277-312
pubmed: 24209443
Biol Trace Elem Res. 2003 Sep;94(3):193-201
pubmed: 12972687
Orphanet J Rare Dis. 2018 Jan 30;13(1):28
pubmed: 29382362
Med Hypotheses. 2005;65(3):607-16
pubmed: 15913899
Oxid Med Cell Longev. 2017;2017:7156928
pubmed: 28811866
Sci Total Environ. 1998 May 27;216(3):253-70
pubmed: 9646532
J Neuropathol Exp Neurol. 2007 Aug;66(8):675-82
pubmed: 17882011
Neurology. 2018 Sep 11;91(11):e1022-e1030
pubmed: 30097475
Expert Rev Neurother. 2020 Nov;20(11):1109-1121
pubmed: 32799578
Metab Brain Dis. 2020 Oct;35(7):1101-1108
pubmed: 32643093
J Biol Chem. 2019 Dec 13;294(50):19197-19208
pubmed: 31699897
J Neurosci. 2009 Mar 11;29(10):3200-5
pubmed: 19279257
Psychiatry Res. 2014 Dec 15;220(1-2):418-25
pubmed: 25064383
Neurotoxicology. 2011 Aug;32(4):450-7
pubmed: 21453724
J Occup Environ Hyg. 2014;11(4):210-7
pubmed: 24579750
Toxicol Lett. 2007 Sep 10;173(2):88-100
pubmed: 17669604
Int J Mol Sci. 2021 Dec 03;22(23):
pubmed: 34884881
Pediatr Neurol. 2007 Mar;36(3):181-3
pubmed: 17352953
Environ Toxicol Pharmacol. 2010 May;29(3):314-9
pubmed: 21787619
Ind Health. 2016;54(1):79-86
pubmed: 26423330
J Biol Chem. 2020 Mar 6;295(10):3040-3054
pubmed: 32001620
PLoS One. 2009 Nov 18;4(11):e7792
pubmed: 19924247
Diabetes. 2016 Sep;65(9):2639-51
pubmed: 27284109
ACS Omega. 2023 Apr 27;8(18):16439-16449
pubmed: 37179629
J Biochem Mol Toxicol. 2016 Feb;30(2):97-105
pubmed: 26418576
Curr Top Cell Regul. 1984;24:153-69
pubmed: 6149889
Br J Ind Med. 1971 Jan;28(1):78-82
pubmed: 5101169
Biol Trace Elem Res. 1996 May;52(2):171-9
pubmed: 8773758
Science. 2008 Feb 15;319(5865):962-5
pubmed: 18276893
Environ Res. 2014 Aug;133:232-8
pubmed: 24971720
Environ Health Perspect. 2010 Oct;118(10):1465-70
pubmed: 20936744
J Trace Elem Med Biol. 2017 Sep;43:9-14
pubmed: 27707611
Front Cell Infect Microbiol. 2013 Dec 05;3:91
pubmed: 24367765
Pharmacol Ther. 2007 Feb;113(2):369-77
pubmed: 17084903
Yakugaku Zasshi. 2004 Sep;124(9):577-85
pubmed: 15340179
Prog Neurobiol. 2001 Sep;65(1):1-105
pubmed: 11369436
Int J Hyg Environ Health. 2011 Dec;215(1):26-35
pubmed: 21820957
Int J Mol Sci. 2021 Nov 11;22(22):
pubmed: 34830074
Neurotoxicology. 2014 Dec;45:260-6
pubmed: 24374477
Environ Res. 2010 Jul;110(5):497-504
pubmed: 20381026
Neurotoxicology. 2018 Jan;64:267-277
pubmed: 28450057
PLoS One. 2012;7(1):e30918
pubmed: 22295119
Diabetes Metab. 2004 Apr;30(2):121-38
pubmed: 15223984
Dalton Trans. 2009 Jun 7;(21):4069-76
pubmed: 19452053
Sci Total Environ. 2012 Sep 1;433:362-70
pubmed: 22819887
Med Hypotheses. 2006;66(1):200-1
pubmed: 16165310
Arch Gynecol Obstet. 2009 Sep;280(3):415-23
pubmed: 19169697
Mol Neurobiol. 2014 Dec;50(3):1098-110
pubmed: 24777576
Cell Death Dis. 2020 Oct 8;11(10):834
pubmed: 33033239
Toxicol Ind Health. 2019 Jan;35(1):53-62
pubmed: 30466360
Environ Health Perspect. 2015 Jul;123(7):717-22
pubmed: 25734517
Ann Hematol. 1999 Oct;78(10):483-4
pubmed: 10550562
Cancers (Basel). 2022 Aug 10;14(16):
pubmed: 36010852
Int J Hyg Environ Health. 2012 Jul;215(4):449-57
pubmed: 22341685
Metallomics. 2010 Feb;2(2):117-25
pubmed: 21069142
Nutrients. 2021 Dec 31;14(1):
pubmed: 35011060
Am J Ind Med. 2007 Nov;50(11):788-800
pubmed: 17918215
Int J Mol Sci. 2021 Oct 28;22(21):
pubmed: 34769138
Adv Neurobiol. 2017;18:13-34
pubmed: 28889261
Toxicology. 2012 Feb 26;292(2-3):90-8
pubmed: 22154916
Br J Nutr. 2009 Apr;101(8):1200-8
pubmed: 19007448