Effects of an App-Based Mindfulness Intervention during Pregnancy on the Infant's Prenatal Androgen Exposure: A Randomized Controlled Pilot Trial.
digit ratio
mindfulness
prenatal programming
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
23 Sep 2023
23 Sep 2023
Historique:
received:
23
08
2023
revised:
18
09
2023
accepted:
20
09
2023
medline:
14
10
2023
pubmed:
14
10
2023
entrez:
14
10
2023
Statut:
epublish
Résumé
Prenatal androgen exposure modulates the development of the brain, with lasting effects on its function and behavior over the infant's life span. Environmental factors during pregnancy, in particular maternal stress, have been shown to influence the androgen load of the unborn child. We here addressed the research gap on whether a mindfulness intervention or a pregnancy education administered to pregnant women more affects the androgen exposure of the unborn child (quantified by the proxies of second-to-fourth digit length ratio (2D:4D) and anogenital distance assessed one year after delivery and at delivery, respectively). Moreover, we tested the mindfulness intervention's effects on maternal perceived stress, anxiety, depressiveness, and mindfulness. Pregnant women (gestation weeks 8-14) were randomized to a 15-week app-based mindfulness-oriented intervention (
Identifiants
pubmed: 37834786
pii: jcm12196142
doi: 10.3390/jcm12196142
pmc: PMC10573842
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Federal Ministry of Education and Research
ID : 01GL1745B
Organisme : Deutsche Forschungsgemeinschaft
ID : GRK2162 / 270949263
Organisme : Deutsche Forschungsgemeinschaft
ID : TRR265 - Project-ID 402170461
Organisme : University of Erlangen-Nuremberg
ID : Open Access Publication Funding
Références
Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16289-94
pubmed: 21896736
Psychoneuroendocrinology. 2019 Jun;104:49-54
pubmed: 30802710
Front Psychiatry. 2018 Aug 07;9:351
pubmed: 30131728
J Neural Transm (Vienna). 2019 May;126(5):623-636
pubmed: 31028478
Sci Rep. 2020 Nov 9;10(1):19326
pubmed: 33168880
J Child Psychol Psychiatry. 2007 Mar-Apr;48(3-4):245-61
pubmed: 17355398
Addict Biol. 2018 May;23(3):904-920
pubmed: 28776866
J Affect Disord. 2019 Jan 15;243:381-390
pubmed: 30266030
J Pediatr. 1987 Aug;111(2):240-3
pubmed: 3612396
BMC Pregnancy Childbirth. 2016 Jan 15;16:5
pubmed: 26772181
J Psychosom Res. 2022 Jun;157:110790
pubmed: 35367919
Early Hum Dev. 2013 Feb;89(2):107-12
pubmed: 23017880
Horm Behav. 2009 Jan;55(1):235-9
pubmed: 19022257
Physiol Behav. 2013 Apr 10;114-115:14-20
pubmed: 23499769
Perspect Psychol Sci. 2018 Jan;13(1):36-61
pubmed: 29016274
Early Hum Dev. 2007 Feb;83(2):87-90
pubmed: 16814493
Psychoneuroendocrinology. 2013 Jun;38(6):907-15
pubmed: 23046825
JMIR Ment Health. 2022 Feb 21;9(2):e31116
pubmed: 35188471
Endocrinology. 2009 Nov;150(11):5119-24
pubmed: 19819951
BMC Psychiatry. 2015 Aug 25;15:206
pubmed: 26303960
Eur Arch Psychiatry Clin Neurosci. 2023 Sep;273(6):1243-1254
pubmed: 36449103
Psychoneuroendocrinology. 2015 Jun;56:148-56
pubmed: 25827959
J Clin Endocrinol Metab. 2011 Sep;96(9):E1502-6
pubmed: 21752894
Psychol Rep. 2007 Feb;100(1):115-26
pubmed: 17451014
J Am Acad Child Adolesc Psychiatry. 2007 Jun;46(6):737-746
pubmed: 17513986
Best Pract Res Clin Obstet Gynaecol. 2014 Jan;28(1):3-12
pubmed: 24140480
Horm Behav. 2020 Apr;120:104686
pubmed: 32014464
J Neurosci. 2012 Feb 15;32(7):2241-7
pubmed: 22396398
Clin Psychopharmacol Neurosci. 2016 May 31;14(2):148-52
pubmed: 27121425
Early Hum Dev. 2023 Jun;181:105776
pubmed: 37084692
Andrology. 2013 Jan;1(1):94-9
pubmed: 23258636
Horm Behav. 2020 Nov;126:104867
pubmed: 32998030
Early Hum Dev. 2004 Apr;77(1-2):23-8
pubmed: 15113628
Eur J Neurosci. 2015 May;41(9):1157-66
pubmed: 25784297
Psychol Bull. 2021 Aug;147(8):749-786
pubmed: 34898233
Toxicol Sci. 2001 Aug;62(2):236-49
pubmed: 11452136
Int J Environ Res Public Health. 2021 Apr 29;18(9):
pubmed: 33947132
Psychoneuroendocrinology. 2007 May;32(4):313-21
pubmed: 17400395
Geburtshilfe Frauenheilkd. 2018 Dec;78(12):1283-1291
pubmed: 30686833
Horm Behav. 2006 Mar;49(3):315-9
pubmed: 16143332
BMC Pregnancy Childbirth. 2022 Apr 8;22(1):301
pubmed: 35395734
J Neurosci. 2012 Jan 11;32(2):674-80
pubmed: 22238103
BMC Psychiatry. 2016 May 23;16:159
pubmed: 27216151
Lancet. 2014 Nov 15;384(9956):1800-19
pubmed: 25455250
J Affect Disord. 2023 Aug 15;335:216-227
pubmed: 37156275
Br J Clin Psychol. 2020 Nov;59(4):461-479
pubmed: 32715513
Midwifery. 2016 May;36:70-9
pubmed: 27106946
Andrology. 2016 Jul;4(4):616-25
pubmed: 26846869
J Pediatr Endocrinol Metab. 2020 Oct 09;34(1):79-88
pubmed: 33035191
Early Hum Dev. 2006 Jul;82(7):469-75
pubmed: 16473482
JAMA Psychiatry. 2019 Jul 1;76(7):700-707
pubmed: 30994877
Aust N Z J Psychiatry. 2020 Apr;54(4):423-432
pubmed: 31957479
Mindfulness (N Y). 2017;8(6):1421-1437
pubmed: 29201244
Behav Neurosci. 2008 Apr;122(2):273-81
pubmed: 18410167
J Womens Health (Larchmt). 2015 May;24(5):384-93
pubmed: 25751609
J Behav Addict. 2017 Mar 1;6(1):30-41
pubmed: 28358645
Acta Psychiatr Scand. 2017 Jul;136(1):96-107
pubmed: 28383757
Front Psychiatry. 2017 Nov 20;8:213
pubmed: 29249989
Physiol Behav. 2010 Mar 30;99(4):433-7
pubmed: 19958785
J Affect Disord. 1996 Jul 29;39(3):185-9
pubmed: 8856422
Addict Biol. 2020 Mar;25(2):e12866
pubmed: 31859437
Horm Behav. 2011 Aug;60(3):256-63
pubmed: 21664359
PLoS One. 2021 Mar 9;16(3):e0248368
pubmed: 33690629
J Neural Transm (Vienna). 2018 Feb;125(2):239-246
pubmed: 29164314
Biol Sex Differ. 2017 Apr 12;8:11
pubmed: 28413602
J Neural Transm (Vienna). 2016 Dec;123(12):1499-1503
pubmed: 27565149
J Affect Disord. 2023 Jul 1;332:262-272
pubmed: 37054897
Biol Psychiatry. 2012 Nov 15;72(10):839-47
pubmed: 22763187
Endocrinology. 1959 Sep;65:369-82
pubmed: 14432658
J Clin Endocrinol Metab. 2015 Mar;100(3):E508-17
pubmed: 25514102
Endocrinology. 2015 Oct;156(10):3435-41
pubmed: 26241065
Proc Biol Sci. 2005 Jul 22;272(1571):1473-9
pubmed: 16011922
Horm Behav. 2016 Feb;78:86-94
pubmed: 26542674
Autism Res. 2012 Aug;5(4):221-30
pubmed: 22674640
Int J Environ Res Public Health. 2020 Nov 13;17(22):
pubmed: 33203014
J Med Internet Res. 2023 Feb 10;25:e41298
pubmed: 36763452
Am J Hum Biol. 2010 Sep-Oct;22(5):619-30
pubmed: 20737609
Arch Womens Ment Health. 2016 Feb;19(1):125-32
pubmed: 25971851
Sci Rep. 2021 Apr 14;11(1):8157
pubmed: 33854119
Psychoneuroendocrinology. 2022 Nov;145:105913
pubmed: 36081227
Dtsch Med Wochenschr. 1998 Jan 16;123(3):35-40
pubmed: 9472218
J Affect Disord. 2016 Jul 15;199:163-70
pubmed: 27107891
Front Endocrinol (Lausanne). 2014 Jan 30;5:9
pubmed: 24523714
Asian J Psychiatr. 2023 Feb;80:103321
pubmed: 36423436
Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13498-503
pubmed: 12370412