Inflammatory Markers as Predictors of Atrial Fibrillation Recurrence: Exploring the C-Reactive Protein to Albumin Ratio in Cryoablation Patients.
C-reactive protein
CRP albumin ratio
atrial fibrillation
cryoablation
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
30 Sep 2023
30 Sep 2023
Historique:
received:
12
08
2023
revised:
17
09
2023
accepted:
26
09
2023
medline:
14
10
2023
pubmed:
14
10
2023
entrez:
14
10
2023
Statut:
epublish
Résumé
Atrial fibrillation (AF) is a common cardiac rhythm disorder associated with hemodynamic disruptions and thromboembolic events. While antiarrhythmic drugs are often recommended as the initial treatment, catheter ablation has emerged as a viable alternative. However, the recurrence of AF following ablation remains a challenge, and there is growing interest in exploring inflammatory markers as predictors of recurrence. This retrospective, cross-sectional analysis included 249 patients who underwent cryoablation for paroxysmal AF. The relationship between the 'C-reactive protein (CRP) to albumin ratio (CAR)' and AF recurrence was examined. Two hundred and forty-nine patients with paroxysmal non-valvular atrial fibrillation were included. They were divided into two groups: those without recurrence (Group 1) and those with recurrence (Group 2). Significant differences were observed in age (57.2 ± 9.9 vs. 62.5 ± 8.4, Inflammation plays a crucial role in the initiation and progression of AF. This study demonstrated that along with age, the CAR can serve as an independent predictor of AF recurrence following cryoablation.
Sections du résumé
BACKGROUND
BACKGROUND
Atrial fibrillation (AF) is a common cardiac rhythm disorder associated with hemodynamic disruptions and thromboembolic events. While antiarrhythmic drugs are often recommended as the initial treatment, catheter ablation has emerged as a viable alternative. However, the recurrence of AF following ablation remains a challenge, and there is growing interest in exploring inflammatory markers as predictors of recurrence.
METHODS
METHODS
This retrospective, cross-sectional analysis included 249 patients who underwent cryoablation for paroxysmal AF. The relationship between the 'C-reactive protein (CRP) to albumin ratio (CAR)' and AF recurrence was examined.
RESULTS
RESULTS
Two hundred and forty-nine patients with paroxysmal non-valvular atrial fibrillation were included. They were divided into two groups: those without recurrence (Group 1) and those with recurrence (Group 2). Significant differences were observed in age (57.2 ± 9.9 vs. 62.5 ± 8.4,
CONCLUSIONS
CONCLUSIONS
Inflammation plays a crucial role in the initiation and progression of AF. This study demonstrated that along with age, the CAR can serve as an independent predictor of AF recurrence following cryoablation.
Identifiants
pubmed: 37834958
pii: jcm12196313
doi: 10.3390/jcm12196313
pmc: PMC10573371
pii:
doi:
Types de publication
Journal Article
Langues
eng
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
J Am Coll Cardiol. 2012 Dec 4;60(22):2263-70
pubmed: 23194937
J Arrhythm. 2023 Jul 04;39(4):515-522
pubmed: 37560294
Clin Med (Lond). 2009 Feb;9(1):30-3
pubmed: 19271597
Int J Biol Macromol. 2021 Aug 1;184:857-862
pubmed: 34181998
Circulation. 2022 Mar 15;145(11):796-804
pubmed: 34933570
J Am Coll Cardiol. 2003 Jul 16;42(2):185-97
pubmed: 12875749
N Engl J Med. 2021 Jan 28;384(4):305-315
pubmed: 33197159
Med Sci Monit. 2022 Jan 27;28:e934569
pubmed: 35082255
Eur Heart J. 2021 Feb 1;42(5):373-498
pubmed: 32860505
Front Nutr. 2021 Aug 18;8:728353
pubmed: 34490334
Ann Surg Oncol. 2021 Jun;28(6):3055-3056
pubmed: 33095364
Cardiovasc Res. 2014 May 1;102(2):258-69
pubmed: 24728497
Clin Res Cardiol. 2021 Jun;110(6):775-788
pubmed: 33089361
J Cardiovasc Electrophysiol. 2011 Sep;22(9):987-93
pubmed: 21489023
Biosci Rep. 2020 Jan 31;40(1):
pubmed: 31815281
Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029618824418
pubmed: 30808220
J Med Invest. 2021;68(3.4):244-255
pubmed: 34759138
JACC Basic Transl Sci. 2019 Sep 23;4(5):640-654
pubmed: 31768479
Front Physiol. 2021 Jul 02;12:686507
pubmed: 34276406
Expert Rev Cardiovasc Ther. 2017 Aug;15(8):601-618
pubmed: 28724315
PLoS One. 2015 Jul 06;10(7):e0129274
pubmed: 26147984
Circ Res. 2014 Apr 25;114(9):1453-68
pubmed: 24763464
J Emerg Med. 1999 Nov-Dec;17(6):1019-25
pubmed: 10595891
Rev Assoc Med Bras (1992). 2020 Aug;66(8):1070-1076
pubmed: 32935800
Heart. 2019 Dec;105(24):1860-1867
pubmed: 31444267
Eur Heart J. 2013 Sep;34(35):2746-51
pubmed: 23900699
Circulation. 2001 Dec 11;104(24):2886-91
pubmed: 11739301
Clin Appl Thromb Hemost. 2015 Jan;21(1):5-9
pubmed: 24431383
Med Sci Monit. 2016 Nov 16;22:4393-4400
pubmed: 27848931
Circulation. 2019 Mar 5;139(10):e56-e528
pubmed: 30700139
Curr Vasc Pharmacol. 2015;13(2):192-201
pubmed: 24188486
Ageing Res Rev. 2016 Nov;31:1-8
pubmed: 27592340
Scand Cardiovasc J. 2019 Apr;53(2):83-90
pubmed: 30835559
PLoS One. 2013;8(3):e59321
pubmed: 23555017
Can J Cardiol. 2020 Dec;36(12):1847-1948
pubmed: 33191198
Kidney Int. 1997 Sep;52(3):761-70
pubmed: 9291198