High Nutritional Risk Is Associated with Poor Functional Status and Prognostic Biomarkers in Stroke Patients at Admission to a Rehabilitation Unit.
CONUT
GNRI
PNI
inflammation
malnutrition
older patients
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
25 Sep 2023
25 Sep 2023
Historique:
received:
30
08
2023
revised:
21
09
2023
accepted:
22
09
2023
medline:
23
10
2023
pubmed:
14
10
2023
entrez:
14
10
2023
Statut:
epublish
Résumé
Considering that malnutrition (undernutrition) is common in stroke patients and may negatively impact body function, the aim of this study was to determine the relationship between nutritional risk and functional status in stroke patients at admission to a rehabilitation unit. Nutritional risk was assessed using the Geriatric Nutritional Risk Index (GNRI), the Prognostic Nutritional Index (PNI) and the Controlling Nutritional Status (CONUT) score. Functional status was assessed using the Barthel Index, the modified Rankin Scale, the Trunk Control Test and the Sitting Balance Scale, and cognitive function was assessed using the Short Portable Mental Status Questionnaire. C-reactive protein, fibrinogen and D-dimer were also evaluated as established prognostic biomarkers. Stroke patients (n = 245; age 69.7 ± 12.8 years; 47%, women; 82% ischemic stroke) at admission to a rehabilitation unit were included in this study. A high prevalence of nutritional risk was detected with each tool and was found to be greater using the GNRI and in patients aged ≥75 years. Multiple logistic regression analysis showed that age and dysphagia were independent predictors of high nutritional risk. High risk groups performed worse on all functional tests compared to the low-risk groups (
Identifiants
pubmed: 37836427
pii: nu15194144
doi: 10.3390/nu15194144
pmc: PMC10574786
pii:
doi:
Substances chimiques
C-Reactive Protein
9007-41-4
Biomarkers
0
Fibrinogen
9001-32-5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
J Am Geriatr Soc. 1975 Oct;23(10):433-41
pubmed: 1159263
Clin Nutr. 2017 Feb;36(1):49-64
pubmed: 27642056
Cerebrovasc Dis. 2023;52(3):318-343
pubmed: 36279857
Nutr Metab Cardiovasc Dis. 2023 Aug;33(8):1501-1510
pubmed: 37336716
J Stroke Cerebrovasc Dis. 2018 Mar;27(3):716-723
pubmed: 29126759
J Acad Nutr Diet. 2019 May;119(5):840-855
pubmed: 30660633
Nutrients. 2023 Jan 29;15(3):
pubmed: 36771390
Nutrients. 2022 Jun 09;14(12):
pubmed: 35745121
Arch Phys Med Rehabil. 2020 May;101(5):852-860
pubmed: 31891712
Lancet. 2023 Mar 18;401(10380):951-966
pubmed: 36716756
Nutrients. 2022 Nov 15;14(22):
pubmed: 36432512
Nutrients. 2022 Oct 12;14(20):
pubmed: 36296943
Nutrients. 2021 May 23;13(6):
pubmed: 34070955
Clin Nutr. 2019 Feb;38(1):10-47
pubmed: 30005900
Front Neurol. 2023 Mar 09;14:1067706
pubmed: 36970524
Diabetes. 2020 Sep;69(9):1961-1973
pubmed: 32540876
Lancet Neurol. 2021 Oct;20(10):795-820
pubmed: 34487721
Stroke. 2007 Mar;38(3):1091-6
pubmed: 17272767
Nutrition. 2023 May;109:111971
pubmed: 36745968
Stroke. 1990 Jan;21(1):82-6
pubmed: 2300995
J Pain Symptom Manage. 2013 Aug;46(2):201-6
pubmed: 23159683
BMC Geriatr. 2021 Dec 4;21(1):676
pubmed: 34863118
Neurocrit Care. 2018 Dec;29(3):374-384
pubmed: 28799021
Front Neurol. 2023 Jun 05;14:1199814
pubmed: 37342777
J Cachexia Sarcopenia Muscle. 2022 Apr;13(2):1036-1044
pubmed: 35166066
Clin Nutr. 2017 Aug;36(4):1089-1096
pubmed: 27426415
J Stroke Cerebrovasc Dis. 2023 Aug;32(8):107207
pubmed: 37295174
Physiother Theory Pract. 2015 Jan;31(1):39-44
pubmed: 25096157
J Nutr Health Aging. 2022;26(6):590-597
pubmed: 35718868
Front Neurol. 2022 Feb 01;12:780080
pubmed: 35178021
Lancet Neurol. 2006 Jul;5(7):603-12
pubmed: 16781990
Am J Clin Nutr. 2008 Jan;87(1):106-13
pubmed: 18175743
Clin Nutr. 2018 Feb;37(1):354-396
pubmed: 29274834
Front Nutr. 2022 Feb 14;9:816167
pubmed: 35237641