Pretreatment Modified Glasgow Prognostic Score for Predicting Prognosis and Survival in Elderly Patients with Gastric Cancer Treated with Perioperative FLOT.
FLOT
elderly
gastric cancer
modified Glasgow prognostic score
neoadjuvant chemotherapy
prognosis
survival
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
26 Sep 2023
26 Sep 2023
Historique:
received:
26
08
2023
revised:
15
09
2023
accepted:
20
09
2023
medline:
23
10
2023
pubmed:
14
10
2023
entrez:
14
10
2023
Statut:
epublish
Résumé
The adverse effects of chemotherapy are more apparent in elderly patients and lead to worse prognosis and mortality. Identifying immunonutritional risk factors is of great importance in terms of treatment effectiveness, prognosis, and mortality in geriatric oncology. The modified Glasgow prognostic score (mGPS) is an immunonutritional index based on serum CRP and albumin levels. In this study, we aimed to investigate the role of mGPS in predicting prognosis and survival in elderly patients with gastric cancer receiving perioperative FLOT treatment. We retrospectively enrolled 71 patients aged over 65 years and grouped them according to their pretreatment mGPS score. Kaplan-Meier and Cox regression analysis showed overall survival was significantly worse in the mGPS 1 and mGPS 2 groups than in the mGPS 0 group (
Identifiants
pubmed: 37836440
pii: nu15194156
doi: 10.3390/nu15194156
pmc: PMC10574228
pii:
doi:
Substances chimiques
C-Reactive Protein
9007-41-4
Serum Albumin
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
In Vivo. 2022 Mar-Apr;36(2):942-948
pubmed: 35241553
Surg Today. 2023 Jan;53(1):22-30
pubmed: 35781553
Eur J Clin Nutr. 2020 Nov;74(11):1519-1535
pubmed: 32366995
Langenbecks Arch Surg. 2022 Nov;407(7):2703-2714
pubmed: 35932298
Oncotarget. 2016 Jun 7;7(23):35423-36
pubmed: 27097114
Exp Ther Med. 2023 Mar 21;25(5):202
pubmed: 37090072
Curr Gastroenterol Rep. 2017 Aug;19(8):36
pubmed: 28730504
J Gastrointest Cancer. 2023 Jan 12;:
pubmed: 36633775
Sci Rep. 2023 May 12;13(1):7755
pubmed: 37173358
N Engl J Med. 2006 Jul 6;355(1):11-20
pubmed: 16822992
World J Surg. 2023 Sep;47(9):2213-2220
pubmed: 37140610
In Vivo. 2018 Nov-Dec;32(6):1667-1672
pubmed: 30348732
Lancet. 2019 May 11;393(10184):1948-1957
pubmed: 30982686
Cancer Med. 2023 Jan;12(1):38-48
pubmed: 35702873
Aging (Albany NY). 2021 Jan 6;13(1):1410-1421
pubmed: 33406501
Cancer Diagn Progn. 2021 May 3;1(2):43-52
pubmed: 35403127
Panminerva Med. 2017 Dec;59(4):302-307
pubmed: 28001023
BMC Cancer. 2020 Jun 3;20(1):517
pubmed: 32493247
BMC Surg. 2022 Jun 3;22(1):213
pubmed: 35655198
Am J Clin Nutr. 2005 Oct;82(4):777-83
pubmed: 16210706
Cancers (Basel). 2019 Apr 12;11(4):
pubmed: 31013858
J Acad Nutr Diet. 2012 May;112(5):730-8
pubmed: 22709779
J Cancer. 2018 Jan 6;9(4):660-666
pubmed: 29556323
Front Surg. 2023 Jan 09;9:1094973
pubmed: 36700011
Nutr Cancer. 2021;73(2):230-238
pubmed: 32270713
JAMA Oncol. 2023 Aug 1;9(8):1048-1055
pubmed: 37347489
Respir Investig. 2023 Jan;61(1):74-81
pubmed: 36460585
CA Cancer J Clin. 2021 May;71(3):209-249
pubmed: 33538338
Tech Coloproctol. 2023 May;27(5):397-405
pubmed: 36197565
J Cancer. 2021 Jan 1;12(2):397-403
pubmed: 33391436
J Clin Oncol. 2003 Oct 1;21(19):3647-50
pubmed: 14512396
Int J Colorectal Dis. 2007 Aug;22(8):881-6
pubmed: 17245566
Arab J Urol. 2020 Aug 26;19(1):2-8
pubmed: 33763243
Cancer Manag Res. 2018 Nov 26;10:6285-6294
pubmed: 30568490
Am J Surg. 2011 Feb;201(2):186-91
pubmed: 20832047
Sci Rep. 2018 Aug 22;8(1):12561
pubmed: 30135506
J Clin Oncol. 2011 May 1;29(13):1715-21
pubmed: 21444866
J Clin Oncol. 2012 Nov 1;30(31):3834-40
pubmed: 23008291
Arch Med Sci. 2017 Jun;13(4):851-863
pubmed: 28721154
Ann Surg. 2004 Aug;240(2):205-13
pubmed: 15273542
Aging Dis. 2022 Apr 1;13(2):379-388
pubmed: 35371597
BMJ Open. 2018 Apr 12;8(4):e019750
pubmed: 29654013
Cancer Manag Res. 2019 Jul 04;11:6163-6173
pubmed: 31308752
Front Immunol. 2022 Feb 08;13:827788
pubmed: 35211122
Ann Clin Biochem. 2013 Sep;50(Pt 5):457-64
pubmed: 23880621
Front Oncol. 2022 Jan 19;11:791912
pubmed: 35127498
PLoS One. 2020 Jul 27;15(7):e0236445
pubmed: 32716955
Am J Clin Pathol. 2021 Oct 13;156(5):749-765
pubmed: 34273159
Lancet Oncol. 2014 Oct;15(11):e493-503
pubmed: 25281468
Clin Pract (Lond). 2021;18(2):1626-1632
pubmed: 33972830
Nutr Cancer. 2020;72(7):1146-1154
pubmed: 31617767