A Rare Case of Myxedema Coma Precipitated by a Single Dose of Haloperidol in a Patient With Paranoid Schizophrenia.
antipsychotic use
endocrine disorder
haldol
hypothalamic-pituitary axis
hypothyroid myxedema coma
severe hypothyroid states
thyroid dysfunction
thyroid replacement therapy
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
accepted:
13
09
2023
medline:
16
10
2023
pubmed:
16
10
2023
entrez:
16
10
2023
Statut:
epublish
Résumé
Myxedema coma is a rare and potentially life-threatening condition that occurs when severe hypothyroidism is untreated or inadequately managed. It is characterized by a rapid drop in mental status, hypothermia, respiratory failure, hypotension, and other symptoms of severe metabolic dysfunction. The condition primarily affects older women with a history of thyroid dysfunction but can occur in any age or gender group. A common trigger for this condition is seen with a drop in atmospheric temperatures or during the cold winter months. However, a rare, poorly documented trigger is recent antipsychotic use in severe hypothyroid states. The diagnosis of myxedema coma requires prompt recognition and treatment, as delays can result in significant morbidity and mortality which is the objective of this case report.
Identifiants
pubmed: 37842468
doi: 10.7759/cureus.45190
pmc: PMC10571067
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e45190Informations de copyright
Copyright © 2023, Menendez et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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