Aftermath of Chlamydia Trachomatis - The Tip of an Iceberg in Female Reproductive Health.
Chlamydia trachomatis
Infertility
PCR
prevalence
Journal
Journal of mother and child
ISSN: 2719-535X
Titre abrégé: J Mother Child
Pays: Poland
ID NLM: 101771247
Informations de publication
Date de publication:
01 Jun 2023
01 Jun 2023
Historique:
received:
13
03
2023
accepted:
10
09
2023
medline:
23
10
2023
pubmed:
16
10
2023
entrez:
16
10
2023
Statut:
epublish
Résumé
The magnitude of infertile couples worldwide was found to be 60-80 million. Genital infection due to Chlamydia trachomatis (C. trachomatis) is one of the most prevalent sexually transmitted infections (STIs) which may present as PID, leading to ectopic pregnancy, infertility or other adverse health outcomes. This study was done to assess the prevalence of C. trachomatis infections among female patients with infertility using real time PCR (RT-PCR) and to compare the findings of molecular testing with hysterosalpingography (HSG) and ultrasonography (USG). 50 endocervical swabs were collected from women of reproductive age group attending infertility clinic and stored at -80 ºC. DNA extraction was done with Helini bacterial mini spin kit and tested for C. trachomatis DNA by RT-PCR kit. Of the 50 patients, 43 (86%) had primary infertility, and 7 (14%) had secondary infertility. Three (6%) were positive for C. trachomatis by RT-PCR. Two had primary infertility and one had secondary infertility. Routine screening of C. trachomatis even in high-risk populations is not available in developing countries like India. The World Health Organization recommends syndromic approach for case management. Hence, a cost-effective, highly sensitive and specific test is the pressing priority in resource poor settings.
Identifiants
pubmed: 37843972
pii: jmotherandchild.20232701.d-23-00033
doi: 10.34763/jmotherandchild.20232701.d-23-00033
pmc: PMC10578464
doi:
Substances chimiques
DNA
9007-49-2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
102-106Informations de copyright
© 2023 Aparnna Vaikundam Subramanian et al., published by Sciendo.
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