Detailed Phytochemical Evaluation of a Locally Endemic Species (Campanula baskilensis) by LC-MS/MS and Its In-Depth Antioxidant and Enzyme Inhibitory Activities.

Campanula baskilensis LC-MS/MS antioxidant bioactivity enzyme inhibition

Journal

Chemistry & biodiversity
ISSN: 1612-1880
Titre abrégé: Chem Biodivers
Pays: Switzerland
ID NLM: 101197449

Informations de publication

Date de publication:
17 Oct 2023
Historique:
received: 08 08 2023
accepted: 15 10 2023
pubmed: 17 10 2023
medline: 17 10 2023
entrez: 17 10 2023
Statut: aheadofprint

Résumé

The importance of bioactive plant species in the scientific world is increasing day by day. The relationship between health and traditional-modern life, promotes the creation of new value-added natural products. This is the first research to conduct a bioactivity and chemical composition analysis of Campanula baskilensis species, which belongs to the medicinally important genus Campanula L (Campanulaceae). The aim of the current study is to quantitatively investigate the phytochemical contents of aerial and root parts of different C. baskilensis extracts (ethanol, methanol, and water) by LC-MS/MS and to evaluate their total phenolic and flavonoid contents, antioxidant and enzyme inhibitory activities. Remarkably, LC-MS/MS results revealed that, high amounts of quinic acid (53.6 mg/g aerial-MeOH extract), fumaric acid (6.3 mg/g aerial-H

Identifiants

pubmed: 37846496
doi: 10.1002/cbdv.202301182
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202301182

Subventions

Organisme : Dicle University Science and Technology Application and Research Center (DUBTAM)

Informations de copyright

© 2023 Wiley-VHCA AG, Zurich, Switzerland.

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Auteurs

Mustafa Abdullah Yilmaz (MA)

Department of Analytical Chemistry, Faculty of Pharmacy, Dicle University, Diyarbakir, 21280, Turkiye.
Dicle University Science and Technology Application and Research Center (DUBTAM), Diyarbakir, 21280, Turkiye.

Oğuz Cakir (O)

Department of Nutrition and Dietetics, Ataturk Faculty of Health Sciences, Dicle University, Diyarbakir, 21280, Turkiye.

Ebubekir Izol (E)

Bee and Natural Products R & D and P & D Application and Research Center, Bingol University, Bingol, 12000, Turkiye.

Abbas Tarhan (A)

Dicle University Science and Technology Application and Research Center (DUBTAM), Diyarbakir, 21280, Turkiye.

Lutfi Behcet (L)

Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Bingol University, Bingol, 12000, Turkiye.

Gokhan Zengin (G)

Department of Biology, Science Faculty, Selcuk University, Konya, 42130, Turkiye.

Classifications MeSH