Aptasensors: employing molecular probes for precise medical diagnostics and drug monitoring.

aptasensors biomaterial analysis biosensors diagnosis personalized medicine therapeutic monitoring

Journal

Bioanalysis
ISSN: 1757-6199
Titre abrégé: Bioanalysis
Pays: England
ID NLM: 101512484

Informations de publication

Date de publication:
Dec 2023
Historique:
medline: 27 11 2023
pubmed: 17 10 2023
entrez: 17 10 2023
Statut: ppublish

Résumé

Accurate detection and monitoring of therapeutic drug levels are vital for effective patient care and treatment management. Aptamers, composed of single-stranded DNA or RNA molecules, are integral components of biosensors designed for both qualitative and quantitative detection of biological samples. Aptasensors play crucial roles in target identification, validation, detection of drug-target interactions and screening potential of drug candidates. This review focuses on the pivotal role of aptasensors in early disease detection, particularly in identifying biomarkers associated with various diseases such as cancer, infectious diseases and cardiovascular disorders. Aptasensors have demonstrated exceptional potential in enhancing disease diagnostics and monitoring therapeutic drug levels. Aptamer-based biosensors represent a transformative technology in the field of healthcare, enabling precise diagnostics, drug monitoring and disease detection.

Identifiants

pubmed: 37847048
doi: 10.4155/bio-2023-0141
doi:

Substances chimiques

Molecular Probes 0
Aptamers, Nucleotide 0
Biomarkers 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1439-1460

Auteurs

Zainab Lafi (Z)

Pharmacological & Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, 19328, Jordan.

Lobna Gharaibeh (L)

Pharmacological & Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, 19328, Jordan.

Hamdi Nsairat (H)

Pharmacological & Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, 19328, Jordan.

Nisreen Asha (N)

Cell Therapy Center, The University of Jordan, Amman, 11942, Jordan.

Walhan Alshaer (W)

Cell Therapy Center, The University of Jordan, Amman, 11942, Jordan.

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Classifications MeSH