Sargachromenol Attenuates Inflammatory Responses by Regulating NF-κB and Nrf2 Pathways in RAW 264.7 Cells and LPS-treated Mice.
Journal
Planta medica
ISSN: 1439-0221
Titre abrégé: Planta Med
Pays: Germany
ID NLM: 0066751
Informations de publication
Date de publication:
17 Oct 2023
17 Oct 2023
Historique:
medline:
18
10
2023
pubmed:
18
10
2023
entrez:
17
10
2023
Statut:
aheadofprint
Résumé
This study aims to explore the anti-inflammatory mechanisms of sargachromenol in both RAW 264.7 cells and lipopolysaccharide (LPS)-treated mice, as previous reports have suggested that sargachromenol possesses anti-aging, anti-inflammatory, antioxidant, and neuroprotective properties. Although the precise mechanism behind its anti-inflammatory activity remains unclear, pretreatment with sargachromenol effectively reduced the production of nitric oxide, prostaglandin E
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Korea Institute of Marine Science and Technology promotion
ID : 20220252
Organisme : National Research Foundation of Korea
ID : NRF-2021R1A6A1A03039211
Organisme : Korea Coast Guard
ID : 20210004
Informations de copyright
Thieme. All rights reserved.
Déclaration de conflit d'intérêts
The authors declare that they have no conflict of interest.