Quantitative
Block sequential regularized expectation maximization (BSREM)
CZT digital detectors
Calibration
Dosimetry
Image reconstruction
Quantitative Lu-177 SPECT
SPECT/CT
Journal
EJNMMI physics
ISSN: 2197-7364
Titre abrégé: EJNMMI Phys
Pays: Germany
ID NLM: 101658952
Informations de publication
Date de publication:
18 Oct 2023
18 Oct 2023
Historique:
received:
07
08
2023
accepted:
12
10
2023
medline:
19
10
2023
pubmed:
19
10
2023
entrez:
18
10
2023
Statut:
epublish
Résumé
Dosimetry after radiopharmaceutical therapy with A series of The accuracy of the activity from the cylinder, although affected by septal penetration, was < 10% for all reconstructions. Both algorithms featured improved spatial resolution and higher RCs with increasing updates at the cost of noise build-up, but Q.Clear outperformed GE-OSEM in reducing noise accumulation. When the reconstruction parameters were carefully selected, similar values for noise (~0.15), spatial resolution (~1 cm) and RCs were found, irrespective of the reconstruction algorithm. Analogue results were found in patients. Accurate activity quantification is possible when imaging
Sections du résumé
BACKGROUND
BACKGROUND
Dosimetry after radiopharmaceutical therapy with
METHODS
METHODS
A series of
RESULTS
RESULTS
The accuracy of the activity from the cylinder, although affected by septal penetration, was < 10% for all reconstructions. Both algorithms featured improved spatial resolution and higher RCs with increasing updates at the cost of noise build-up, but Q.Clear outperformed GE-OSEM in reducing noise accumulation. When the reconstruction parameters were carefully selected, similar values for noise (~0.15), spatial resolution (~1 cm) and RCs were found, irrespective of the reconstruction algorithm. Analogue results were found in patients.
CONCLUSIONS
CONCLUSIONS
Accurate activity quantification is possible when imaging
Identifiants
pubmed: 37853247
doi: 10.1186/s40658-023-00586-z
pii: 10.1186/s40658-023-00586-z
pmc: PMC10584798
doi:
Types de publication
Journal Article
Langues
eng
Pagination
64Informations de copyright
© 2023. Springer Nature Switzerland AG.
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