Hepatoprotective Properties of Water Kefir: A Traditional Fermented Drink and Its Potential Role.
Antioxidant
hepatoprotector
inflammation
probiotic
water kefir
Journal
International journal of preventive medicine
ISSN: 2008-7802
Titre abrégé: Int J Prev Med
Pays: Iran
ID NLM: 101535380
Informations de publication
Date de publication:
2023
2023
Historique:
received:
26
01
2022
accepted:
01
11
2022
medline:
19
10
2023
pubmed:
19
10
2023
entrez:
19
10
2023
Statut:
epublish
Résumé
The liver is extremely vulnerable to damage because of its role in metabolism. Toxin, metabolic syndrome, alcohol, microorganisms, and autoimmune diseases can be the cause of liver damage. While different etiologies can cause liver disease, pathophysiologically, there are similarities in the role of free radicals, inflammatory mediators, and gut microbiome during the disease development. Therefore, ingredients with antioxidant, antiinflammatory, and antidysbiotic properties have the potential to act as hepatoprotectors; and water kefir is one of them. Water kefir is a traditional fermented drink made from water kefir grains, sugar, and dried fruit. Water kefir is dominated by lactic acid bacteria and yeast as a fermented beverage, and several species of this group of microorganisms have been shown as probiotics. According to researches, water kefir has strong antioxidant, antiinflammatory, and hepatoprotective effects. Even so, there are still few researches reported about water kefir as a hepatoprotective agent. Several studies, on the other hand, showed promising results. This review discusses the relationship between the pathophysiology of liver disease and the pharmacological activity of water kefir and other probiotics in general, which leads to the potential prospect of water kefir research as a hepatoprotective agent.
Identifiants
pubmed: 37855014
doi: 10.4103/ijpvm.ijpvm_29_22
pii: IJPVM-14-93
pmc: PMC10580206
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
93Informations de copyright
Copyright: © 2023 International Journal of Preventive Medicine.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
Références
Compr Physiol. 2013 Oct;3(4):1473-92
pubmed: 24265236
Front Microbiol. 2018 Dec 14;9:3063
pubmed: 30619149
PLoS One. 2018 Mar 8;13(3):e0192978
pubmed: 29518093
Microorganisms. 2021 Sep 16;9(9):
pubmed: 34576864
Microb Cell Fact. 2007 Jul 20;6:22
pubmed: 17659075
J Physiol Pharmacol. 2008 Aug;59 Suppl 1:107-17
pubmed: 18802219
Food Chem. 2013 May 1;138(1):84-9
pubmed: 23265459
Gut Microbes. 2020 Nov 9;12(1):1801944
pubmed: 32795116
J Hepatol. 2019 Feb;70(2):260-272
pubmed: 30658727
Appl Microbiol Biotechnol. 2013 Jan;97(2):809-17
pubmed: 22790540
Liver Res. 2021 Sep;5(3):151-163
pubmed: 35355516
Front Immunol. 2017 Nov 17;8:1553
pubmed: 29209314
World J Gastroenterol. 2010 May 7;16(17):2134-45
pubmed: 20440854
Oxid Med Cell Longev. 2016;2016:1340903
pubmed: 27066188
Gastroenterology. 2014 May;146(6):1513-24
pubmed: 24440671
J Food Sci. 2017 Dec;82(12):2960-2967
pubmed: 29131334
Alcohol Res. 2017;38(2):147-161
pubmed: 28988570
J Hepatol. 2019 Jan;70(1):151-171
pubmed: 30266282
J Clin Transl Hepatol. 2016 Jun 28;4(2):131-42
pubmed: 27350943
JHEP Rep. 2019 Jul 31;1(3):214-226
pubmed: 32039372
Lancet. 2012 Dec 15;380(9859):2095-128
pubmed: 23245604
Front Immunol. 2018 May 24;9:1131
pubmed: 29881384
J Appl Microbiol. 2017 Jul;123(1):271-279
pubmed: 28474851
FEMS Microbiol Lett. 2013 Nov;348(1):79-85
pubmed: 24004255
Therap Adv Gastroenterol. 2013 Jan;6(1):39-51
pubmed: 23320049
Front Microbiol. 2019 Mar 13;10:479
pubmed: 30918501
Adv Drug Deliv Rev. 2017 Nov 1;121:3-8
pubmed: 28600202
Biomed Res Int. 2017;2017:8972678
pubmed: 28913359
FEMS Yeast Res. 2011 Jun;11(4):379-87
pubmed: 21375688
Biomed Res Int. 2019 Jan 2;2019:8507583
pubmed: 30719448
PLoS One. 2018 Feb 14;13(2):e0192021
pubmed: 29444150
J Microbiol Biotechnol. 2015 Sep;25(9):1568-77
pubmed: 25951843
Ann Clin Transl Neurol. 2015 Jan;2(1):56-66
pubmed: 25642435
PLoS One. 2012;7(7):e40648
pubmed: 22848391
Gastroenterology. 2013 Aug;145(2):375-82.e1-2
pubmed: 23583430
Appl Environ Microbiol. 2014 Apr;80(8):2564-72
pubmed: 24532061
J Hepatol. 2013 Jul;59(1):160-8
pubmed: 23511777
BMC Complement Altern Med. 2017 Jan 21;17(1):64
pubmed: 28109187
Gastroenterology. 2019 Oct;157(4):1109-1122
pubmed: 31255652
Front Microbiol. 2012 Dec 19;3:421
pubmed: 23267352
PLoS One. 2012;7(12):e52493
pubmed: 23300685
Exp Mol Med. 2019 Aug 13;51(8):1-14
pubmed: 31409765
Microb Biotechnol. 2022 Jan;15(1):247-261
pubmed: 33492728
Gut. 2016 Dec;65(12):2035-2044
pubmed: 27802157
Integr Cancer Ther. 2016 Dec;15(4):NP53-NP66
pubmed: 27230756
Fungal Genet Biol. 2020 Apr;137:103333
pubmed: 31923554
Free Radic Biol Med. 2016 May;94:55-65
pubmed: 26898146
Foods. 2020 Aug 21;9(9):
pubmed: 32825754
BMC Med. 2014 Sep 18;12:145
pubmed: 25242656
Int J Food Microbiol. 2011 Dec 15;151(3):284-8
pubmed: 22000549
FEMS Microbiol Lett. 1996 Aug 1;141(2-3):207-12
pubmed: 8768524
Sci Rep. 2020 Jul 14;10(1):11572
pubmed: 32665600
Front Microbiol. 2018 Nov 06;9:2684
pubmed: 30459744
Int J Mol Sci. 2015 Nov 02;16(11):26087-124
pubmed: 26540040
Nutr Clin Pract. 2020 Feb;35(1):24-29
pubmed: 31840297