LIPID MAPS: update to databases and tools for the lipidomics community.


Journal

Nucleic acids research
ISSN: 1362-4962
Titre abrégé: Nucleic Acids Res
Pays: England
ID NLM: 0411011

Informations de publication

Date de publication:
19 Oct 2023
Historique:
accepted: 04 10 2023
revised: 03 10 2023
received: 12 09 2023
medline: 19 10 2023
pubmed: 19 10 2023
entrez: 19 10 2023
Statut: aheadofprint

Résumé

LIPID MAPS (LIPID Metabolites and Pathways Strategy), www.lipidmaps.org, provides a systematic and standardized approach to organizing lipid structural and biochemical data. Founded 20 years ago, the LIPID MAPS nomenclature and classification has become the accepted community standard. LIPID MAPS provides databases for cataloging and identifying lipids at varying levels of characterization in addition to numerous software tools and educational resources, and became an ELIXIR-UK data resource in 2020. This paper describes the expansion of existing databases in LIPID MAPS, including richer metadata with literature provenance, taxonomic data and improved interoperability to facilitate FAIR compliance. A joint project funded by ELIXIR-UK, in collaboration with WikiPathways, curates and hosts pathway data, and annotates lipids in the context of their biochemical pathways. Updated features of the search infrastructure are described along with implementation of programmatic access via API and SPARQL. New lipid-specific databases have been developed and provision of lipidomics tools to the community has been updated. Training and engagement have been expanded with webinars, podcasts and an online training school.

Identifiants

pubmed: 37855672
pii: 7321986
doi: 10.1093/nar/gkad896
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Wellcome Trust
ID : 203014/Z/16/Z]
Pays : United Kingdom
Organisme : NIH HHS
ID : U2CDK119886
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM139641
Pays : United States

Informations de copyright

© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

Auteurs

Matthew J Conroy (MJ)

Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.

Robert M Andrews (RM)

Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.

Simon Andrews (S)

Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK.

Lauren Cockayne (L)

Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.

Edward A Dennis (EA)

Department of Pharmacology, Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0601, USA.

Eoin Fahy (E)

Department of Bioengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92037, USA.

Caroline Gaud (C)

Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK.

William J Griffiths (WJ)

Swansea University Medical School, Singleton Park, Swansea SA2 8PP, Wales, UK.

Geoff Jukes (G)

Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.

Maksim Kolchin (M)

Boehringer Ingelheim Espana SA, Carrer de Prat de la Riba, 50, 08174 Sant Cugat del Vallès, Barcelona, Spain.

Karla Mendivelso (K)

Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.

Andrea F Lopez-Clavijo (AF)

Babraham Institute, Babraham Research Campus, Cambridge CB22 3AT, UK.

Caroline Ready (C)

Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.

Shankar Subramaniam (S)

Department of Bioengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92037, USA.

Valerie B O'Donnell (VB)

Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff CF14 4XN, UK.

Classifications MeSH