Ischemia-Modified Albumin and Antioxidant Protection in Newborns with Asphyxia of Varying Severity.
antioxidant capacity of blood serum
ischemia-modified albumin
newborns with asphyxia
oxidative stress
serum albumin
Journal
Bulletin of experimental biology and medicine
ISSN: 1573-8221
Titre abrégé: Bull Exp Biol Med
Pays: United States
ID NLM: 0372557
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
21
02
2023
medline:
2
11
2023
pubmed:
19
10
2023
entrez:
19
10
2023
Statut:
ppublish
Résumé
The content of ischemia-modified albumin (IMA), serum albumin, and antioxidant capacity of blood serum was studied in healthy newborns and in newborns with moderate and severe asphyxia on days 1-2 and 3-4 of the postnatal period. Changes in these indicators were found in both groups of newborns with birth asphyxia in comparison with the group of healthy newborns and were more pronounced in children with severe asphyxia. An increase in the IMA level (by 1.6 times; p<0.001) and antioxidant capacity of blood serum (by 2.4 times; p<0.001) and a decrease in serum albumin content (by 1.5 times; p<0.001) were found in severe asphyxia on days 1-2. Analysis of changes in these indicators by days 3-4 allows to talk about a decrease in the intensity of free-radical reactions in newborns with birth asphyxia during complex therapy.
Identifiants
pubmed: 37855865
doi: 10.1007/s10517-023-05913-z
pii: 10.1007/s10517-023-05913-z
doi:
Substances chimiques
ischemia-modified albumin
0
Serum Albumin
0
Biomarkers
0
Antioxidants
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
620-624Informations de copyright
© 2023. Springer Science+Business Media, LLC, part of Springer Nature.
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