Long-term exposure to low-level air pollution and greenness and mortality in Northern Europe. The Life-GAP project.

Humans Nitrogen Dioxide Air Pollution Ozone Europe Particulate Matter / adverse effects Soot Air Pollutants / adverse effects Environmental Exposure / adverse effects
Green space Long-term effect Nitrogen dioxide Ozone Particulate matter Premature mortality

Journal

Environment international
ISSN: 1873-6750
Titre abrégé: Environ Int
Pays: Netherlands
ID NLM: 7807270

Informations de publication

Date de publication:
Nov 2023
Historique:
received: 13 04 2023
revised: 28 09 2023
accepted: 09 10 2023
medline: 20 11 2023
pubmed: 20 10 2023
entrez: 19 10 2023
Statut: ppublish

Résumé

Air pollution has been linked to mortality, but there are few studies examining the association with different exposure time windows spanning across several decades. The evidence for the effects of green space and mortality is contradictory. We investigated all-cause mortality in relation to exposure to particulate matter (PM The exposure assessment was based on a combination of the Danish Eulerian Hemispheric Model and the Urban Background Model for the years 1990, 2000 and 2010. The analysis included a complete case dataset with 9,135 participants from the third Respiratory Health in Northern Europe study (RHINE III), aged 40-65 years in 2010, with mortality follow-up to 2021. We performed Cox proportional hazard models, adjusting for potential confounders. Altogether, 327 (3.6 %) persons died in the period 2010-2021. Increased exposures in 1990 of PM Long term exposure to even low levels of air pollution is associated with mortality. Opening up for a long latency period, our findings indicate that air pollution exposures over time may be even more harmful than anticipated.

Sections du résumé

BACKGROUND BACKGROUND
Air pollution has been linked to mortality, but there are few studies examining the association with different exposure time windows spanning across several decades. The evidence for the effects of green space and mortality is contradictory.
OBJECTIVE OBJECTIVE
We investigated all-cause mortality in relation to exposure to particulate matter (PM
METHODS METHODS
The exposure assessment was based on a combination of the Danish Eulerian Hemispheric Model and the Urban Background Model for the years 1990, 2000 and 2010. The analysis included a complete case dataset with 9,135 participants from the third Respiratory Health in Northern Europe study (RHINE III), aged 40-65 years in 2010, with mortality follow-up to 2021. We performed Cox proportional hazard models, adjusting for potential confounders.
RESULTS RESULTS
Altogether, 327 (3.6 %) persons died in the period 2010-2021. Increased exposures in 1990 of PM
CONCLUSION CONCLUSIONS
Long term exposure to even low levels of air pollution is associated with mortality. Opening up for a long latency period, our findings indicate that air pollution exposures over time may be even more harmful than anticipated.

Identifiants

DOI: 10.1016/j.envint.2023.108257 PMID: 37857189
pubmed: 37857189
pii: S0160-4120(23)00530-5
doi: 10.1016/j.envint.2023.108257
pii:
doi:

Substances chimiques

Nitrogen Dioxide S7G510RUBH
Ozone 66H7ZZK23N
Particulate Matter 0
Soot 0
Air Pollutants 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108257

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Shanshan Xu (S)

Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway. Electronic address: shanshan.xu@uib.no.

Alessandro Marcon (A)

Unit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Verona, Italy.

Randi Jacobsen Bertelsen (RJ)

Department of Clinical Science, University of Bergen, Bergen, Norway.

Bryndis Benediktsdottir (B)

Department of Respiratory Medicine and Sleep, Landspitali - the National University Hospital of Iceland, Reykjavik, Iceland.

Jørgen Brandt (J)

Department of Environmental Science, Aarhus University, Roskilde, Denmark.

Kristine Engemann (K)

Section for Ecoinformatics & Biodiversity, Department of Bioscience, Aarhus University, Aarhus C, Denmark.

Lise Marie Frohn (LM)

Department of Environmental Science, Aarhus University, Roskilde, Denmark.

Camilla Geels (C)

Department of Environmental Science, Aarhus University, Roskilde, Denmark.

Thorarinn Gislason (T)

Department of Respiratory Medicine and Sleep, Landspitali - the National University Hospital of Iceland, Reykjavik, Iceland.

Joachim Heinrich (J)

Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany; Allergy and Lung Health Unit, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia.

Mathias Holm (M)

Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Christer Janson (C)

Department of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.

Iana Markevych (I)

Institute of Psychology, Jagiellonian University, Krakow, Poland.

Lars Modig (L)

Department of Public Health and Clinical Medicine, Section of Sustainable Health, Umeå University, Sweden.

Hans Orru (H)

Department of Public Health, Institute of Family Medicine and Public Health, Faculty of Medicine, University of Tartu, Tartu, Estonia.

Vivi Schlünssen (V)

Department of Public Health, Research Unit for Environment Occupation and Health, Danish Ramazzini Center, Aarhus University, Aarhus, Denmark.

Torben Sigsgaard (T)

Department of Public Health, Research Unit for Environment Occupation and Health, Danish Ramazzini Center, Aarhus University, Aarhus, Denmark.

Ane Johannessen (A)

Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Long-term exposure to low-level air pollution...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Oxydes d'azote › Dioxyde d'azote › Long-term exposure to low-level air pollution...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Pollution de l'air › Long-term exposure to low-level air pollution...
questionsmedicales.fr › Produits chimiques inorganiques › Gaz › Oxygène › Ozone › Long-term exposure to low-level air pollution...
questionsmedicales.fr › Régions géographiques › Europe › Long-term exposure to low-level air pollution...
questionsmedicales.fr › Mélanges complexes › Matière particulaire › Long-term exposure to low-level air pollution...
questionsmedicales.fr › Mélanges complexes › Matière particulaire › Fumée › Suie › Long-term exposure to low-level air pollution...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Polluants environnementaux › Polluants atmosphériques › Long-term exposure to low-level air pollution...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pollution de l'environnement › Exposition environnementale › Long-term exposure to low-level air pollution...