Habitual short sleepers with pre-existing medical conditions are at higher risk of Long COVID.

COVID-19 ICOSS II International COVID Sleep Study Survey Long COVID pre-existing medical conditions sleep duration

Journal

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
ISSN: 1550-9397
Titre abrégé: J Clin Sleep Med
Pays: United States
ID NLM: 101231977

Informations de publication

Date de publication:
03 Oct 2023
Historique:
medline: 20 10 2023
pubmed: 20 10 2023
entrez: 20 10 2023
Statut: aheadofprint

Résumé

Preliminary evidence suggests that the risk of Long COVID is higher among people with pre-existing medical conditions. Based on its proven adjuvant role in immunity, habitual sleep duration may alter the risk for developing Long COVID. The objective of this study was to determine whether the odds of Long COVID are higher amongst those with pre-existing medical conditions, and whether the strength of this association varies by habitual sleep duration. Using data from 13,461 respondents from 16 countries who participated in the 2021 survey based International COVID Sleep Study II (ICOSS II), we studied the associations between habitual sleep duration, pre-existing medical conditions, and Long COVID. Of 2,508 individuals who had COVID-19, 61% reported at least one Long COVID symptom. Multivariable logistic regression analysis showed that the risk of having Long COVID was 1.8-fold higher for average-length sleepers (6-9h/night) with pre-existing medical conditions compared to those without pre-existing medical conditions [aOR 1.84 (1.18-2.90), P=0.008]. The risk of Long COVID was 3-fold higher for short sleepers with pre-existing medical conditions [aOR 2.95 (1.04-8.4), P=0.043] and not significantly higher for long sleepers with pre-existing conditions [aOR 2.11 (0.93-4.77), P=0.073] compared to average-length sleepers without pre-existing conditions. Habitual short nighttime sleep duration exacerbated the risk of Long COVID in individuals with pre-existing conditions. Restoring nighttime sleep to average duration represents a potentially modifiable behavioral factor to lower the odds of Long COVID for at-risk patients.

Identifiants

DOI: 10.5664/jcsm.10818 PMID: 37858285
pubmed: 37858285
doi: 10.5664/jcsm.10818
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023 American Academy of Sleep Medicine.

Auteurs

Linor Berezin (L)

Department of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada.

Rida Waseem (R)

Department of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada.

Ilona Merikanto (I)

SleepWell Research Program, Faculty of Medicine, University of Helsinki, Orton Orthopaedics Hospital, Helsinki, Finl and.

Christian Benedict (C)

Department of Pharmaceutical Biosciences, Molecular Neuropharmacology, Uppsala University, Sweden.

Brigitte Holzinger (B)

Institute for Consciousness and Dream Research; Medical University of Vienna, Wien, Postgraduate Sleep Coaching, Vienna, Austria.

Luigi De Gennaro (L)

Department of Psychology, Sapienza University of Rome, Roma, Lazio, Italy.
IRCCS Fondazione Santa Lucia, Roma, Italy.

Yun Kwok Wing (YK)

Li Chiu Kong Family Sleep Assessment Unit, Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.

Bjørn Bjorvatn (B)

Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Norwegian Competence Center for Sleep Disorders, Haukeland University Hospital, Bergen, Norway.

Maria Korman (M)

Department of Occupational Therapy, Faculty of Health Sciences, Ariel University, Ariel, Israel.

Charles M Morin (CM)

Centre de recherche CERVO/Brain Research Center, École de psychologie, Université Laval, Canada.

Colin Espie (C)

Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

Anne-Marie Landtblom (AM)

Department of Medical Sciences, Neurology, Uppsala University, Uppsala, Sweden.
Department of Biomedical and Clinical Sciences, Linköping University, Sweden.

Thomas Penzel (T)

Sleep Medicine Center, Charite University Hospital Berlin, Berlin, Germany.

Kentaro Matsui (K)

Department of Clinical Laboratory, National Center Hospital, National Center of Neurology and Psychiatry, Kodaira, Japan.

Harald Hrubos-Strøm (H)

Department of Otorhinolaryngology, Akershus University Hospital, Lørenskog, Norway.
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Sérgio Mota-Rolim (S)

Brain Institute, Physiology and Behavior Department, and Onofre Lopes University Hospital Federal University of Rio Grande do Norte, Brazil.

Michael R Nadorff (MR)

Department of Psychology, Mississippi State University, Mississippi State, Mississippi.

Giuseppe Plazzi (G)

IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna, Italy.
Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.

Catia Reis (C)

Universidade Católica Portuguesa, Católica Research Centre for Psychological Family and Social Welbeing, Lisbon, Portugal.
Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Lisboa, Portugal.
Instituto de Saúde Ambiental, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.

Rachel Ngan Yin Chan (RNY)

Li Chiu Kong Family Sleep Assessment Unit, Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.

Ana Suely Cunha (AS)

Medical College, Potiguar University, Natal, Brazil.

Juliana Yordanova (J)

Institute of Neurobiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.

Adrijana Koscec Bjelajac (AK)

Institute for Medical Research and Occupational Health, Zagreb, Croatia.

Yuichi Inoue (Y)

Department of Somnology, Tokyo Medical University, Tokyo, Japan.
Japan Somnology Center, Institute of Neuropsychiatry, Tokyo, Japan.

Yves Dauvilliers (Y)

Sleep-Wake Disorders Center, Department of Neurology, Guide Chauliac Hospital, Institute for Neurosciences of Montpellier INM, INSERM, University of Montpellier, Montpellier, France.

Markku Partinen (M)

Department of Clinical Neurosciences, University of Helsinki Clinicum Unit, Helsinki, Finl and.
Helsinki Sleep Clinic, Terveystalo Healthcare Services, Helsinki, Finl and.

Frances Chung (F)

Department of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada.

Classifications MeSH