MONITORING PERFUSION-BASED CONVECTION IN CANCER TUMOR TISSUE UNDERGOING NANOPARTICLE HEATING BY ANALYZING TEMPERATURE RESPONSES TO TRANSIENT PULSED HEATING.
Bio-heat and mass transfer
magnetic nanoparticle heating
natural and mixed convection
perfusion
Journal
Proceedings of the ASME Summer Heat Transfer Conference. ASME Summer Heat Transfer Conference
Titre abrégé: Proc ASME Summer Heat Transf Conf
Pays: United States
ID NLM: 9918697485506676
Informations de publication
Date de publication:
Jul 2023
Jul 2023
Historique:
medline:
20
10
2023
pubmed:
20
10
2023
entrez:
20
10
2023
Statut:
ppublish
Résumé
The dynamic nature of perfusion in living tissues, such as solid tumors during thermal therapy, produces challenging spatiotemporal thermal boundary conditions. Changes in perfusion can manifest as changes in convective heat transfer that influence temperature changes during cyclic heating. Herein, we propose a method to actively monitor changes in local convection (perfusion) in vivo by using a transient thermal pulsing analysis. Syngeneic 4T1 tumor cells were injected subcutaneously into BALB/c mice and followed by caliper measurements. When tumor volumes measured 150-400 mm
Identifiants
pubmed: 37860628
doi: 10.1115/ht2023-105470
pmc: PMC10585666
mid: NIHMS1898488
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : NCI NIH HHS
ID : R01 CA247290
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA257557
Pays : United States
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