Multifunctional nano MOF drug delivery platform in combination therapy.

Drug Delivery Systems Metal-Organic Frameworks / pharmacology Combined Modality Therapy Nanotechnology
Cancer therapy Combination therapy Drug delivery Metal-organic frameworks

Journal

European journal of medicinal chemistry
ISSN: 1768-3254
Titre abrégé: Eur J Med Chem
Pays: France
ID NLM: 0420510

Informations de publication

Date de publication:
05 Dec 2023
Historique:
received: 27 08 2023
revised: 11 10 2023
accepted: 14 10 2023
medline: 3 11 2023
pubmed: 21 10 2023
entrez: 20 10 2023
Statut: ppublish

Résumé

Recent preclinical and clinical studies have demonstrated that for cancer treatment, combination therapies are more effective than monotherapies in reducing drug-related toxicity, decreasing drug resistance, and improving therapeutic efficacy. With the rapid development of nanotechnology, the combination of metal-organic frameworks (MOFs) and multi-mode therapy offers a realistic possibility to further improve the shortcomings of cancer treatment. This article focuses on the latest developments, achievements, and treatment strategies of representative multifunctional MOF combination therapies for cancer treatment in recent years, which include not only bimodal combination therapies, but also multi-modal synergistic therapies, further demonstrating the effectiveness and superiority of the MOF drug delivery systems in cancer treatment.

Identifiants

DOI: 10.1016/j.ejmech.2023.115884 PMID: 37862817
pubmed: 37862817
pii: S0223-5234(23)00851-6
doi: 10.1016/j.ejmech.2023.115884
pii:
doi:

Substances chimiques

Metal-Organic Frameworks 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

115884

Informations de copyright

Copyright © 2023 Elsevier Masson SAS. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest We declare that we have no financial and personal relationships with other people or organizations that can inappropriately influence our work, there is no professional or other personal interest of any nature or kind in any product, service and/or company that could be construed as influencing the position presented in, or the review of, the manuscript entitled.

Auteurs

Dongwei Ma (D)

Guangxi Scientific Research Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning, 530200, China; Guangxi Zhuang Yao Medicine Center of Engineering and Technology, Nanning, 530200, China.

Gang Wang (G)

Guangxi Scientific Research Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning, 530200, China; Guangxi Zhuang Yao Medicine Center of Engineering and Technology, Nanning, 530200, China.

Jingsheng Lu (J)

Guangxi Scientific Research Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning, 530200, China; Guangxi Zhuang Yao Medicine Center of Engineering and Technology, Nanning, 530200, China.

Xiaoxuan Zeng (X)

Guangxi Scientific Research Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning, 530200, China; Guangxi Zhuang Yao Medicine Center of Engineering and Technology, Nanning, 530200, China.

Yanwei Cheng (Y)

Guangxi Scientific Research Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning, 530200, China; Guangxi Zhuang Yao Medicine Center of Engineering and Technology, Nanning, 530200, China.

Zhenwei Zhang (Z)

College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530200, China; Guangxi Zhuang Yao Medicine Center of Engineering and Technology, Nanning, 530200, China.

Ning Lin (N)

College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530200, China; Guangxi Zhuang Yao Medicine Center of Engineering and Technology, Nanning, 530200, China. Electronic address: linning@gxtcmu.edu.cn.

Qing Chen (Q)

Guangxi Scientific Research Center of Traditional Chinese Medicine, Guangxi University of Chinese Medicine, Nanning, 530200, China; Guangxi Zhuang Yao Medicine Center of Engineering and Technology, Nanning, 530200, China. Electronic address: chenqing@gxtcmu.edu.cn.

Articles similaires

Transarterial chemoembolization combined with molecular targeted agents plus immune checkpoint inhibitors for unresectable hepatocellular carcinoma beyond the up-to-seven criteria: a propensity score-matching analysis.

Wen Chen, Hai-Tao Yan, Jin-Xing Zhang et al.
1.00
Humans Carcinoma, Hepatocellular Chemoembolization, Therapeutic Liver Neoplasms Male

Mathematical modeling of vancomycin release from Poly-L-Lactic Acid-Coated implants.

Papon Thamvasupong, Kwanchanok Viravaidya-Pasuwat
1.00
Vancomycin Polyesters Anti-Bacterial Agents Models, Theoretical Drug Liberation

The efficacy of combined physiotherapeutic scoliosis-specific exercises and manual therapy in adolescent idiopathic scoliosis.

Zou Wenxia, Li Yuelong, Zhang Zhou et al.
1.00
Humans Scoliosis Adolescent Female Male

Folate-engineered chitosan nanoparticles: next-generation anticancer nanocarriers.

Prashant Kesharwani, Kratika Halwai, Saurav Kumar Jha et al.
1.00
Chitosan Humans Folic Acid Nanoparticles Drug Carriers

Classifications MeSH

questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Multifunctional nano MOF drug delivery...
questionsmedicales.fr › Structures macromoléculaires › Réseaux organométalliques › Multifunctional nano MOF drug delivery...
questionsmedicales.fr › Thérapeutique › Association thérapeutique › Multifunctional nano MOF drug delivery...
questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Miniaturisation › Nanotechnologie › Multifunctional nano MOF drug delivery...