Mast Cell Disorders of the Gastrointestinal Tract: Clarity out of Chaos.
Irritable bowel syndrome
Mast cell activation syndrome
Mast cell enterocolitis
Mast cells
Systemic mastocytosis
Journal
Surgical pathology clinics
ISSN: 1875-9157
Titre abrégé: Surg Pathol Clin
Pays: United States
ID NLM: 101491209
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
medline:
1
11
2023
pubmed:
21
10
2023
entrez:
20
10
2023
Statut:
ppublish
Résumé
Pathologists are increasingly asked to evaluate mast cell infiltrates in the gastrointestinal tract when there is clinical concern for systemic mastocytosis or a variety of functional disorders, including irritable bowel syndrome and mast cell activation syndrome. Neoplastic mast cells have established quantitative, morphologic, and immunohistochemical features that facilitate their identification in gastrointestinal mucosal biopsies. Specific qualitative and quantitative findings are lacking for inflammatory mast cell-mediated disorders. This review covers histopathologic features of mast cell disorders that affect the gastrointestinal tract and offers practical guidance for their assessment in mucosal biopsies.
Identifiants
pubmed: 37863564
pii: S1875-9181(23)00050-8
doi: 10.1016/j.path.2023.05.010
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
755-764Informations de copyright
Copyright © 2023 Elsevier Inc. All rights reserved.