Transversus Abdominis Plane Block VS. Local Wound Infiltration for Elective Minimally Invasive Cholecystectomy in Children: A Prospective Randomized Trial.

Analgesia Cholecystectomy Laparoscopic Opioid Pain Robotic

Journal

Journal of pediatric surgery
ISSN: 1531-5037
Titre abrégé: J Pediatr Surg
Pays: United States
ID NLM: 0052631

Informations de publication

Date de publication:
22 Sep 2023
Historique:
received: 17 08 2023
accepted: 06 09 2023
medline: 21 10 2023
pubmed: 21 10 2023
entrez: 20 10 2023
Statut: aheadofprint

Résumé

The efficacy of transversus abdominis plane (TAP) block versus local anesthetic wound infiltration (LWI) in pediatric laparoscopic surgery is largely unknown. The objective of this study was to prospectively analyze this in minimally invasive cholecystectomy. We hypothesized that TAP block would be superior to LWI in terms of pain control and post-operative complications. We conducted a prospective, randomized, single-blinded, controlled trial between 2017 and 2022 after obtaining Institutional Review Board (IRB) approval. After randomization, patients received a standard amount of ropivacaine via either 1) ultrasound-guided TAP block after general anesthesia induction or 2) local injection at port insertion by the operating surgeon. We collected data including operative time, pain scores, and medication usage post-operatively. We used descriptive statistics to report all endpoints and compared data with t-tests and Fisher's exact tests. A p-value less than 0.05 was considered statistically significant. We enrolled 85 patients (43 LWI, 42 TAP). Mean [standard deviation] age and body mass index (BMI) in the LWI and TAP groups were 14.8 [1.9] and 14.7 [2] years and 29.9 [7.2] and 27.4 [8.2] kilogram/meter There are no significant differences between equal administration of local anesthetic by TAP block and surgeon administered LWI during minimally invasive cholecystectomy. Randomized clinical trial. Level II.

Sections du résumé

BACKGROUND BACKGROUND
The efficacy of transversus abdominis plane (TAP) block versus local anesthetic wound infiltration (LWI) in pediatric laparoscopic surgery is largely unknown. The objective of this study was to prospectively analyze this in minimally invasive cholecystectomy. We hypothesized that TAP block would be superior to LWI in terms of pain control and post-operative complications.
METHODS METHODS
We conducted a prospective, randomized, single-blinded, controlled trial between 2017 and 2022 after obtaining Institutional Review Board (IRB) approval. After randomization, patients received a standard amount of ropivacaine via either 1) ultrasound-guided TAP block after general anesthesia induction or 2) local injection at port insertion by the operating surgeon. We collected data including operative time, pain scores, and medication usage post-operatively. We used descriptive statistics to report all endpoints and compared data with t-tests and Fisher's exact tests. A p-value less than 0.05 was considered statistically significant.
RESULTS RESULTS
We enrolled 85 patients (43 LWI, 42 TAP). Mean [standard deviation] age and body mass index (BMI) in the LWI and TAP groups were 14.8 [1.9] and 14.7 [2] years and 29.9 [7.2] and 27.4 [8.2] kilogram/meter
CONCLUSION CONCLUSIONS
There are no significant differences between equal administration of local anesthetic by TAP block and surgeon administered LWI during minimally invasive cholecystectomy.
TYPE OF STUDY METHODS
Randomized clinical trial.
LEVEL OF EVIDENCE METHODS
Level II.

Identifiants

pubmed: 37863700
pii: S0022-3468(23)00557-2
doi: 10.1016/j.jpedsurg.2023.09.020
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest None.

Auteurs

Sindhu Mannava (S)

Indiana University School of Medicine, Department of Surgery, 705 Riley Hospital Drive, Suite 2500, Indianapolis, IN, USA. Electronic address: svmannava@gmail.com.

Niloufar Hafezi (N)

Indiana University School of Medicine, Department of Surgery, 705 Riley Hospital Drive, Suite 2500, Indianapolis, IN, USA.

Farheen Turk (F)

Indiana University School of Medicine, 705 Riley Hospital Drive, Suite 2500, Indianapolis, IN, USA.

Cameron Colgate (C)

Indiana University School of Medicine, Center for Outcomes Research in Surgery, 545 Barnhill Drive, Emerson Hall, Indianapolis, IN, USA.

Johanna Askegard-Giesmann (J)

University of North Dakota, 5225 23rd Avenue S, Fargo, ND, USA.

Troy Markel (T)

Indiana University School of Medicine, Department of Surgery, Division of Pediatric Surgery, 705 Riley Hospital Drive, Suite 2500, Indianapolis, IN, USA.

Nicole Horn (N)

Indiana University School of Medicine, Department of Anesthesia, 1130 W Michigan Street, Fesler Hall Room 204, Indianapolis, IN, USA.

Brian Gray (B)

Indiana University School of Medicine, Department of Surgery, Division of Pediatric Surgery, 705 Riley Hospital Drive, Suite 2500, Indianapolis, IN, USA.

Classifications MeSH