Flow Cytometric Assessment of Myelodysplastic Syndromes/Neoplasms.

Humans Flow Cytometry Myelodysplastic Syndromes / diagnosis Immunophenotyping Neoplasms
Flow cytometry Immunophenotyping MDS Myelodysplastic syndromes/neoplasms Myeloid maturation

Journal

Clinics in laboratory medicine
ISSN: 1557-9832
Titre abrégé: Clin Lab Med
Pays: United States
ID NLM: 8100174

Informations de publication

Date de publication:
12 2023
Historique:
medline: 31 10 2023
pubmed: 22 10 2023
entrez: 21 10 2023
Statut: ppublish

Résumé

Myelodysplastic syndromes/neoplasms (MDS) are a heterogeneous class of hematopoietic stem cell neoplasms characterized by ineffective hematopoiesis leading to peripheral cytopenias. This group of diseases is typically diagnosed using a combination of clinical, morphologic, and genetic criteria. Many studies have described the value of multiparametric flow cytometry (MFC) in the diagnosis, classification, and prognostication of MDS. This review summarizes the approach to MDS diagnosis and immunophenotypic characterization using MFC and describes the current state while highlighting future opportunities and potential pitfalls.

Identifiants

DOI: 10.1016/j.cll.2023.06.006 PMID: 37865501
pubmed: 37865501
pii: S0272-2712(23)00070-7
doi: 10.1016/j.cll.2023.06.006
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

521-547

Informations de copyright

Crown Copyright © 2023. Published by Elsevier Inc. All rights reserved.

Auteurs

Xueyan Chen (X)

Translational Science and Therapeutics Division, Fred Hutch Cancer Center, Seattle, WA, USA; Department of Laboratory Medicine and Pathology, University of Washington, 825 Eastlake Avenue East, Seattle, WA 98109, USA.

Ulrika Johansson (U)

SI-HMDS, Haematology, UHBW NHS Foundation Trust, Bristol Royal Infirmary, Upper Maudlin Street, Bristol, BS2 8HW, UK.

Sindhu Cherian (S)

Department of Laboratory Medicine and Pathology, University of Washington, 825 Eastlake Avenue East, Seattle, WA 98109, USA. Electronic address: cherians@uw.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Flow Cytometric Assessment of Myelodysplastic...
questionsmedicales.fr › Techniques d'investigation › Techniques cytologiques › Cytophotométrie › Cytométrie en flux › Flow Cytometric Assessment of Myelodysplastic...
questionsmedicales.fr › Hémopathies et maladies lymphatiques › Hémopathies › Maladies de la moelle osseuse › Syndromes myélodysplasiques › Flow Cytometric Assessment of Myelodysplastic...
questionsmedicales.fr › Techniques d'investigation › Techniques immunologiques › Tests immunologiques › Immunophénotypage › Flow Cytometric Assessment of Myelodysplastic...
questionsmedicales.fr › Tumeurs › Flow Cytometric Assessment of Myelodysplastic...