How do gravity alterations affect animal and human systems at a cellular/tissue level?
Journal
NPJ microgravity
ISSN: 2373-8065
Titre abrégé: NPJ Microgravity
Pays: United States
ID NLM: 101703605
Informations de publication
Date de publication:
21 Oct 2023
21 Oct 2023
Historique:
received:
31
12
2022
accepted:
11
10
2023
medline:
22
10
2023
pubmed:
22
10
2023
entrez:
21
10
2023
Statut:
epublish
Résumé
The present white paper concerns the indications and recommendations of the SciSpacE Science Community to make progress in filling the gaps of knowledge that prevent us from answering the question: "How Do Gravity Alterations Affect Animal and Human Systems at a Cellular/Tissue Level?" This is one of the five major scientific issues of the ESA roadmap "Biology in Space and Analogue Environments". Despite the many studies conducted so far on spaceflight adaptation mechanisms and related pathophysiological alterations observed in astronauts, we are not yet able to elaborate a synthetic integrated model of the many changes occurring at different system and functional levels. Consequently, it is difficult to develop credible models for predicting long-term consequences of human adaptation to the space environment, as well as to implement medical support plans for long-term missions and a strategy for preventing the possible health risks due to prolonged exposure to spaceflight beyond the low Earth orbit (LEO). The research activities suggested by the scientific community have the aim to overcome these problems by striving to connect biological and physiological aspects in a more holistic view of space adaptation effects.
Identifiants
pubmed: 37865644
doi: 10.1038/s41526-023-00330-y
pii: 10.1038/s41526-023-00330-y
pmc: PMC10590411
doi:
Types de publication
Journal Article
Langues
eng
Pagination
84Informations de copyright
© 2023. Springer Nature Limited.
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