[COMPLETE REMISSION OF METASTATIC RENAL CELL CARCINOMA AFTER PARTIAL NEPHRECTOMY FOLLOWING PEMBROLIZUMAB PLUS AXITINIB THERAPY: A CASE REPORT].

Axitinib Pembrolizumab renal cell carcinoma

Journal

Nihon Hinyokika Gakkai zasshi. The japanese journal of urology
ISSN: 1884-7110
Titre abrégé: Nihon Hinyokika Gakkai Zasshi
Pays: Japan
ID NLM: 2984841R

Informations de publication

Date de publication:
2022
Historique:
medline: 1 1 2022
pubmed: 1 1 2022
entrez: 22 10 2023
Statut: ppublish

Résumé

This case is a 62-year-old man diagnosed with metastatic renal cell carcinoma. He was referred to our department due to the left renal mass pointed with ultra sound examination. Radiographical examination showed left-side 42 mm renal tumor with multiple lung tumors, suggesting renal cell carcinoma, cT1bN0M1 (pul). As an induction therapy, we selected Pembrolizumab plus Axitinib combination therapy. After 4 course of the therapy, the left kidney tumor shrank to 27 mm, and the lung metastasis disappeared with computed tomography imaging. For the next step, we performed laparoscopic partial nephrectomy. The pathological diagnosis was clear cell carcinoma, grade 2 with central necrosis. Since then, complete remission has been maintained without any treatment for 21 months.

Identifiants

pubmed: 37866934
doi: 10.5980/jpnjurol.113.139
doi:

Types de publication

English Abstract Journal Article

Langues

jpn

Sous-ensembles de citation

IM

Pagination

139-142

Auteurs

Yasuhiro Hakamata (Y)

Department of Urology, Seirei Hamamatsu General Hospital.

Kosuke Uchida (K)

Department of Urology, Seirei Hamamatsu General Hospital.

Taisho Noda (T)

Department of Urology, Seirei Hamamatsu General Hospital.

Shin Imai (S)

Department of Urology, Seirei Hamamatsu General Hospital.

Tatsuaki Yoneda (T)

Department of Urology, Seirei Hamamatsu General Hospital.

Shinya Kudoh (S)

Soramame Nephrology & Urology Clinic.

Classifications MeSH