[COMPLETE REMISSION OF METASTATIC RENAL CELL CARCINOMA AFTER PARTIAL NEPHRECTOMY FOLLOWING PEMBROLIZUMAB PLUS AXITINIB THERAPY: A CASE REPORT].
Axitinib
Pembrolizumab
renal cell carcinoma
Journal
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology
ISSN: 1884-7110
Titre abrégé: Nihon Hinyokika Gakkai Zasshi
Pays: Japan
ID NLM: 2984841R
Informations de publication
Date de publication:
2022
2022
Historique:
medline:
1
1
2022
pubmed:
1
1
2022
entrez:
22
10
2023
Statut:
ppublish
Résumé
This case is a 62-year-old man diagnosed with metastatic renal cell carcinoma. He was referred to our department due to the left renal mass pointed with ultra sound examination. Radiographical examination showed left-side 42 mm renal tumor with multiple lung tumors, suggesting renal cell carcinoma, cT1bN0M1 (pul). As an induction therapy, we selected Pembrolizumab plus Axitinib combination therapy. After 4 course of the therapy, the left kidney tumor shrank to 27 mm, and the lung metastasis disappeared with computed tomography imaging. For the next step, we performed laparoscopic partial nephrectomy. The pathological diagnosis was clear cell carcinoma, grade 2 with central necrosis. Since then, complete remission has been maintained without any treatment for 21 months.
Identifiants
pubmed: 37866934
doi: 10.5980/jpnjurol.113.139
doi:
Types de publication
English Abstract
Journal Article
Langues
jpn
Sous-ensembles de citation
IM