Mouthwashes: Alternatives and Future Directions.
Bacteria
Caries
Gingivitis
Mouthwash
Naturopathic
Novel
Journal
International dental journal
ISSN: 1875-595X
Titre abrégé: Int Dent J
Pays: England
ID NLM: 0374714
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
18
08
2023
accepted:
21
08
2023
medline:
24
11
2023
pubmed:
23
10
2023
entrez:
22
10
2023
Statut:
ppublish
Résumé
This narrative review summarises "alternative" or "natural" over-the-counter (OTC) mouthwashes not covered elsewhere in this supplement and newly emerging products, as potential mouthwashes of the future. The "natural" mouthwashes reviewed include saltwater, baking soda, coconut oil, charcoal, propolis, seaweeds, and probiotics. Other than essential oils, it is apparent that their clinical effectiveness is still under debate, but there is some evidence to suggest that propolis reduces plaque and gingivitis. This review also covers the host immune response, via novel anti-inmmunomodulant mouthwashes, such as erythropoietin to reduce inflammation with oral mucositis (OM) after radiotherapy. The emerging concept of nanoparticle-containing mouthwashes, such as iron oxide, is further discussed for OM, this agent having the potential for more targeted delivery of chemical antimicrobials. Unfortunately, there are impacts on the environment of widening mouthwash use with more new products, including increased use of packaging, antimicrobial resistance, and possible detrimental effects on marine life. Further, there are roadblocks, relating to regularly approvals and side effects, that still need to be overcome for any OTC deivered immunomodulant or nanoformulation mouthwashes. Despite these caveats, there are many new mouthwashes under development, which could help manage major oral diseases such as caries, gingivitis, and periodontal disease.
Identifiants
pubmed: 37867066
pii: S0020-6539(23)00457-4
doi: 10.1016/j.identj.2023.08.011
pmc: PMC10690551
pii:
doi:
Substances chimiques
Mouthwashes
0
Propolis
9009-62-5
Oils, Volatile
0
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
S89-S97Informations de copyright
Copyright © 2023. Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Conflict of interest None disclosed.
Références
J Indian Soc Pedod Prev Dent. 2010 Jul-Sep;28(3):179-82
pubmed: 21157050
Biomater Sci. 2021 Aug 7;9(15):5127-5135
pubmed: 33997876
Colloids Surf B Biointerfaces. 2021 Apr;200:111617
pubmed: 33592455
Nano Lett. 2021 Nov 24;21(22):9442-9449
pubmed: 34694125
Eur Rev Med Pharmacol Sci. 2017 Dec;21(24):5827-5836
pubmed: 29272020
Oral Implantol (Rome). 2017 Apr 10;10(1):59-70
pubmed: 28757937
BMC Oral Health. 2020 Jul 10;20(1):198
pubmed: 32650754
J Clin Pediatr Dent. 2023 Mar;47(2):85-100
pubmed: 36890746
Cancer. 2009 Aug 15;115(16):3699-708
pubmed: 19514089
Probiotics Antimicrob Proteins. 2018 Sep;10(3):485-495
pubmed: 28631250
J Indian Soc Periodontol. 2022 Jan-Feb;26(1):58-63
pubmed: 35136318
BMJ Open. 2022 Dec 20;12(12):e060753
pubmed: 36600415
J Dent Res. 2003 Mar;82(3):206-11
pubmed: 12598550
J Conserv Dent. 2020 Nov-Dec;23(6):624-631
pubmed: 34083921
Int J Mol Sci. 2023 Jan 06;24(2):
pubmed: 36674600
Complement Ther Med. 2019 Dec;47:102193
pubmed: 31780023
J Immunother. 2001 Jul-Aug;24(4):384-8
pubmed: 11565840
Environ Sci Pollut Res Int. 2021 Jul;28(26):34211-34228
pubmed: 33991301
Front Public Health. 2021 Nov 23;9:740800
pubmed: 34888281
J Tradit Complement Med. 2016 Jun 06;7(1):106-109
pubmed: 28053895
Br Dent J. 2020 Feb;228(4):290-294
pubmed: 32112023
Mar Drugs. 2023 Feb 02;21(2):
pubmed: 36827150
Braz J Microbiol. 2010 Jul;41(3):805-9
pubmed: 24031558
J Clin Oncol. 2003 Dec 15;21(24):4546-52
pubmed: 14597742
Trends Biotechnol. 2015 Nov;33(11):621-636
pubmed: 26493710
Nat Rev Microbiol. 2018 Dec;16(12):745-759
pubmed: 30301974
Braz Dent Sci. 2014;17(1):11-15
pubmed: 24971228
Int J Nanomedicine. 2016 May 31;11:2471-80
pubmed: 27330290
J Pharm Bioallied Sci. 2021 Jun;13(Suppl 1):S757-S760
pubmed: 34447196
Hematol Oncol. 2017 Mar;35(1):106-112
pubmed: 26310513
J Prev Med Hyg. 2022 Jul 31;63(2):E282-E287
pubmed: 35968060
Front Pharmacol. 2017 Jun 08;8:354
pubmed: 28642709
Clin Oral Investig. 2019 Apr;23(4):1673-1683
pubmed: 30151705
J Indian Soc Periodontol. 2011 Apr;15(2):121-5
pubmed: 21976834
Environ Sci Pollut Res Int. 2022 Jul;29(32):48736-48747
pubmed: 35199264
Community Dent Oral Epidemiol. 2021 Dec;49(6):581-593
pubmed: 33686705
Clin Oral Investig. 2021 Jul;25(7):4349-4357
pubmed: 33389135
Arch Oral Biol. 1990;35 Suppl:115S-122S
pubmed: 2088214
Clin Cancer Res. 1999 Jun;5(6):1363-8
pubmed: 10389920
Natl J Maxillofac Surg. 2017 Jul-Dec;8(2):106-109
pubmed: 29386812
J Am Dent Assoc. 2017 Nov;148(11S):S1-S3
pubmed: 29056183
Bone Marrow Transplant. 1998 Oct;22(8):781-5
pubmed: 9827976
Eur J Oncol Nurs. 2022 Feb;56:102093
pubmed: 35026498
J Dent Sci. 2022 Jan;17(1):249-255
pubmed: 35028045
J Clin Periodontol. 1997 Nov;24(11):796-8
pubmed: 9402499
Evid Based Dent. 2015 Mar;16(1):27-8
pubmed: 25909940
Niger Med J. 2015 Mar-Apr;56(2):143-7
pubmed: 25838632
Acta Odontol Scand. 2021 Nov;79(8):613-622
pubmed: 33956564
Appl Environ Microbiol. 2006 Oct;72(10):6854-8
pubmed: 16950914
J Endod. 2021 Jun;47(6):939-946
pubmed: 33640425
Phytomed Plus. 2021 Aug;1(3):100043
pubmed: 35399823
Evid Based Complement Alternat Med. 2013;2013:351062
pubmed: 23365605
Mar Drugs. 2022 Feb 15;20(2):
pubmed: 35200670
Front Pharmacol. 2021 Nov 29;12:787633
pubmed: 34912230
PLoS One. 2016 Jul 21;11(7):e0159843
pubmed: 27441729
Int J Dent Hyg. 2022 May;20(2):415-421
pubmed: 35133701
Lifestyle Genom. 2022;15(1):35-44
pubmed: 35021171
Caries Res. 2014;48(3):186-92
pubmed: 24480927
J Endod. 2016 Oct;42(10):1417-26
pubmed: 27520408
J Clin Exp Dent. 2019 Mar 01;11(3):e244-e249
pubmed: 31001394
Pharmaceutics. 2022 Jul 07;14(7):
pubmed: 35890323
Indian J Dent Res. 2018 Sep-Oct;29(5):672-677
pubmed: 30409952
Bioorg Med Chem Lett. 2014 Jun 1;24(11):2530-4
pubmed: 24755428
BMC Oral Health. 2022 Jul 29;22(1):313
pubmed: 35906582
Front Oral Health. 2023 Jan 30;3:977830
pubmed: 36798750
Anaerobe. 2013 Jun;21:34-8
pubmed: 23583539
J Oral Biosci. 2021 Mar;63(1):23-34
pubmed: 33465498
J Indian Soc Pedod Prev Dent. 2017 Oct-Dec;35(4):319-326
pubmed: 28914244
BMC Oral Health. 2021 Sep 23;21(1):465
pubmed: 34556107
Cureus. 2022 Aug 18;14(8):e28125
pubmed: 35990566
Eur J Dent. 2020 Feb;14(1):55-62
pubmed: 32168532
Nat Prod Res. 2018 Jun;32(12):1441-1445
pubmed: 28641462
Crit Rev Microbiol. 2020 Aug;46(4):475-491
pubmed: 32720594
Int J Food Microbiol. 2023 Mar 2;388:110083
pubmed: 36708610
Int J Antimicrob Agents. 2001 Dec;18(6):553-7
pubmed: 11738343
Microb Pathog. 2018 Feb;115:233-238
pubmed: 29277474
Support Care Cancer. 2013 Nov;21(11):3165-77
pubmed: 24018908
Nat Nanotechnol. 2010 Aug;5(8):565-9
pubmed: 20581832