Current Diagnostic and Treatment Methods of Alzheimer's Disease: A Narrative Review.
alzheimer’s
detection of a.d
plaques
risk factors
tangles
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
11
08
2023
accepted:
20
09
2023
medline:
23
10
2023
pubmed:
23
10
2023
entrez:
23
10
2023
Statut:
epublish
Résumé
To diagnose and predict the possibility of Alzheimer's or a different kind of dementia, medical professionals employ tests that look at a patient's mental competence; however, such methods are impracticable. A reliable diagnosis at the start of treatment is essential for therapy. Except in situations with apparent genetic variations, most Alzheimer's patients lack a known etiology. Therefore, every Alzheimer's patient receives the same treatment plan, regardless of the etiology, which may or may not be successful in slowing or preventing the disease's progression. Tau pathology is further complicated by the amyloid buildup that arises from the cellular phase of Alzheimer's disease (AD). Alzheimer's is a degenerative, diverse, complicated, and incurable neurological disorder primarily affecting elderly individuals. The currently accepted drugs available for treating AD, which involve cholinesterase inhibitors and N-methyl-D-aspartate
Identifiants
pubmed: 37868425
doi: 10.7759/cureus.45649
pmc: PMC10589453
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e45649Informations de copyright
Copyright © 2023, Dafre et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Cochrane Database Syst Rev. 2018 Mar 01;3:CD001120
pubmed: 29493789
Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12292-12297
pubmed: 27791018
Curr Top Med Chem. 2017;17(27):3000-3016
pubmed: 28714419
Folia Neuropathol. 2019;57(2):87-105
pubmed: 31556570
Folia Neuropathol. 2013;51(3):169-88
pubmed: 24114635
Molecules. 2020 Dec 08;25(24):
pubmed: 33302541
Therap Adv Gastroenterol. 2016 Mar;9(2):229-39
pubmed: 26929784
Physiol Rev. 2019 Oct 1;99(4):1877-2013
pubmed: 31460832
Lancet. 2005 Dec 17;366(9503):2112-7
pubmed: 16360788
Nat Rev Neurosci. 2002 Oct;3(10):824-8
pubmed: 12360327
Subcell Biochem. 2012;65:329-52
pubmed: 23225010
Neurobiol Aging. 2013 Nov;34(11):2457-64
pubmed: 23769397
Curr Alzheimer Res. 2018 Feb 22;15(4):303-312
pubmed: 28474568
PLoS One. 2014 Jan 27;9(1):e86498
pubmed: 24475133
JAMA Neurol. 2018 Jul 1;75(7):834-841
pubmed: 29582053
Eur J Nucl Med Mol Imaging. 2020 Nov;47(12):2753-2764
pubmed: 32318784
Cold Spring Harb Perspect Med. 2012 Apr;2(4):a006213
pubmed: 22474610
Lancet Neurol. 2022 Aug;21(8):726-734
pubmed: 35643092
Curr Neuropharmacol. 2020;18(11):1106-1125
pubmed: 32484110
Curr Sports Med Rep. 2017 Jan/Feb;16(1):19-22
pubmed: 28067736
Nutrients. 2022 Feb 05;14(3):
pubmed: 35277027
F1000Res. 2018 Jul 31;7:
pubmed: 30135715
Food Chem Toxicol. 2010 Dec;48(12):3289-303
pubmed: 20870006
Mol Biol Rep. 2021 Jul;48(7):5629-5645
pubmed: 34181171
Am J Alzheimers Dis Other Demen. 2020 Jan-Dec;35:1533317520937542
pubmed: 32864980
Psychiatriki. 2019 Apr-Jun;30(2):142-155
pubmed: 31425142
Int J Mol Sci. 2020 Sep 01;21(17):
pubmed: 32882843
J Alzheimers Dis. 2014;38(1):201-9
pubmed: 23948937
Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14052-7
pubmed: 18779561
JAMA Neurol. 2015 Oct;72(10):1139-47
pubmed: 26302439
Toxicol Appl Pharmacol. 2018 Oct 1;356:8-14
pubmed: 30025849
PLoS One. 2019 Sep 17;14(9):e0222505
pubmed: 31527913
Curr Alzheimer Res. 2018;15(12):1106-1113
pubmed: 30101706
Neurobiol Aging. 2014 Jan;35(1):122-9
pubmed: 23916950
Neurosci Lett. 1993 Oct 1;160(2):139-44
pubmed: 8247344
Front Psychol. 2015 Mar 02;6:230
pubmed: 25784891
Eur J Med Chem. 2014 Mar 21;75:21-30
pubmed: 24508831
Sci Rep. 2018 Apr 27;8(1):6670
pubmed: 29703936
Acta Psychiatr Scand. 1988 Sep;78(3):257-75
pubmed: 3057813
Curr Med Chem. 2015;22(3):373-404
pubmed: 25386820
Acta Psychiatr Scand. 1964;40:SUPPL 173:1+
pubmed: 14154723
Biochem Soc Trans. 2005 Nov;33(Pt 5):1041-4
pubmed: 16246041
Biomark Med. 2018 Jul;12(7):799-812
pubmed: 29902934
CNS Drugs. 2013 Jun;27(6):469-78
pubmed: 23733403
Nutrients. 2021 Dec 22;14(1):
pubmed: 35010895
Alzheimers Res Ther. 2016 Feb 17;8:7
pubmed: 26883213
Alzheimers Res Ther. 2023 Mar 27;15(1):65
pubmed: 36973733