Phosphorylated HP1α-Nucleosome Interactions in Phase Separated Environments.


Journal

Journal of the American Chemical Society
ISSN: 1520-5126
Titre abrégé: J Am Chem Soc
Pays: United States
ID NLM: 7503056

Informations de publication

Date de publication:
08 11 2023
Historique:
medline: 9 11 2023
pubmed: 23 10 2023
entrez: 23 10 2023
Statut: ppublish

Résumé

In the nucleus, transcriptionally silent genes are sequestered into heterochromatin compartments comprising nucleosomes decorated with histone H3 Lys9 trimethylation and a protein called HP1α. This protein can form liquid-liquid droplets

Identifiants

pubmed: 37870432
doi: 10.1021/jacs.3c06481
pmc: PMC10636758
doi:

Substances chimiques

Nucleosomes 0
Heterochromatin 0
Histones 0
Chromosomal Proteins, Non-Histone 0
Transcription Factors 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

23994-24004

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Auteurs

Nesreen Elathram (N)

Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.

Bryce E Ackermann (BE)

Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.

Evan T Clark (ET)

Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.

Shelby R Dunn (SR)

Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.

Galia T Debelouchina (GT)

Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.

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Classifications MeSH