Paradoxical inflammatory blepharitis in a patient with Crohn's disease.
Journal
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
ISSN: 1528-3933
Titre abrégé: J AAPOS
Pays: United States
ID NLM: 9710011
Informations de publication
Date de publication:
21 Oct 2023
21 Oct 2023
Historique:
received:
19
06
2023
revised:
24
08
2023
accepted:
28
08
2023
pubmed:
24
10
2023
medline:
24
10
2023
entrez:
23
10
2023
Statut:
aheadofprint
Résumé
We report the case of a 15-year-old boy with severe inflammatory blepharitis who was being treated with a TNFα inhibitor for Crohn's disease (CD). This case shows the potential utility of a skin biopsy in distinguishing metastatic CD associated with granulomatous blepharitis from a paradoxical blepharitis induced by anti-TNFα. It also demonstrates that ustekinumab can be considered in patients with CD who cannot tolerate TNFα inhibitors because of cutaneous paradoxical reactions.
Identifiants
pubmed: 37871794
pii: S1091-8531(23)00217-3
doi: 10.1016/j.jaapos.2023.08.012
pii:
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2023 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.