MAP1B Regulates Cortical Neuron Interstitial Axon Branching Through the Tubulin Tyrosination Cycle.

Interstitial axon branching cortical neuron development intracellular signaling microtubules

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
02 Oct 2023
Historique:
pubmed: 24 10 2023
medline: 24 10 2023
entrez: 24 10 2023
Statut: epublish

Résumé

Regulation of directed axon guidance and branching during development is essential for the generation of neuronal networks. However, the molecular mechanisms that underlie interstitial axon branching in the mammalian brain remain unresolved. Here, we investigate interstitial axon branching

Identifiants

DOI: 10.1101/2023.10.02.560024 PMID: 37873083 PMC: PMC10592918
pubmed: 37873083
doi: 10.1101/2023.10.02.560024
pmc: PMC10592918
pii:
doi:

Types de publication

Preprint

Langues

eng

Déclaration de conflit d'intérêts

DECLARATION OF INTERESTS The authors declare no competing interests. RH currently serves as a Director of Neuroscience at Prilenia Therapeutics. JD currently works at Novartis.

Auteurs

Jakub Ziak (J)

The Solomon H. Snyder Department of Neuroscience, Johns Hopkins Kavli Neuroscience Discovery Institute, The Johns Hopkins School of Medicine, 725 North Wolfe St., Baltimore, MD 21205.

Joelle Dorskind (J)

The Solomon H. Snyder Department of Neuroscience, Johns Hopkins Kavli Neuroscience Discovery Institute, The Johns Hopkins School of Medicine, 725 North Wolfe St., Baltimore, MD 21205.
Novartis Institutes for BioMedical Research, Boston, MA.

Brian Trigg (B)

The Solomon H. Snyder Department of Neuroscience, Johns Hopkins Kavli Neuroscience Discovery Institute, The Johns Hopkins School of Medicine, 725 North Wolfe St., Baltimore, MD 21205.

Sriram Sudarsanam (S)

The Solomon H. Snyder Department of Neuroscience, Johns Hopkins Kavli Neuroscience Discovery Institute, The Johns Hopkins School of Medicine, 725 North Wolfe St., Baltimore, MD 21205.

Randal Hand (R)

The Solomon H. Snyder Department of Neuroscience, Johns Hopkins Kavli Neuroscience Discovery Institute, The Johns Hopkins School of Medicine, 725 North Wolfe St., Baltimore, MD 21205.
Prilenia Therapeutics, Boston, MA.

Alex L Kolodkin (AL)

The Solomon H. Snyder Department of Neuroscience, Johns Hopkins Kavli Neuroscience Discovery Institute, The Johns Hopkins School of Medicine, 725 North Wolfe St., Baltimore, MD 21205.

Classifications MeSH