Immunologic changes are detectable in the peripheral blood transcriptome of clinically asymptomatic Chagas cardiomyopathy patients.


Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
05 Oct 2023
Historique:
pubmed: 24 10 2023
medline: 24 10 2023
entrez: 24 10 2023
Statut: epublish

Résumé

Chagas disease, caused by the protozoan parasite

Identifiants

pubmed: 37873108
doi: 10.1101/2023.10.03.560680
pmc: PMC10592925
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : FIC NIH HHS
ID : D43 TW010074
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI107028
Pays : United States

Déclaration de conflit d'intérêts

Potential conflicts of interest: Y. E. C.-S. reports nonfinancial support from InBios International Inc. during the conduct of the study and outside the submitted work.

Références

Nat Biotechnol. 2019 Jul;37(7):773-782
pubmed: 31061481
Nat Commun. 2019 May 22;10(1):2263
pubmed: 31118448
Acta Trop. 2013 Jan;125(1):23-31
pubmed: 22982466
Front Immunol. 2018 Apr 09;9:486
pubmed: 29686665
Front Immunol. 2019 Apr 18;10:800
pubmed: 31057540
J Infect Dis. 2002 Sep 15;186(6):872-5
pubmed: 12198628
Front Med (Lausanne). 2021 Jul 23;8:681635
pubmed: 34368188
Circulation. 2011 Nov 15;124(20):2264-74
pubmed: 22083148
J Antimicrob Chemother. 2020 Mar 1;75(3):690-696
pubmed: 31754690
Nat Rev Immunol. 2003 Jan;3(1):11-22
pubmed: 12511872
J Immunol. 2023 May 1;210(9):1198-1207
pubmed: 37068299
J Clin Microbiol. 1996 Sep;34(9):2143-7
pubmed: 8862574
PLoS Negl Trop Dis. 2022 May 16;16(5):e0010386
pubmed: 35576215
Innovation (Camb). 2021 Jul 01;2(3):100141
pubmed: 34557778
Trends Mol Med. 2007 Oct;13(10):422-32
pubmed: 17919976
Int J Cardiol. 2015 Jan 15;178:55-62
pubmed: 25442238
Int Immunol. 2002 Oct;14(10):1135-44
pubmed: 12356679
Circulation. 2007 Mar 6;115(9):1109-23
pubmed: 17339569
Parasit Vectors. 2016 Dec 7;9(1):631
pubmed: 27923409
Lancet Infect Dis. 2001 Sep;1(2):92-100
pubmed: 11871482
Front Immunol. 2021 Feb 19;12:584538
pubmed: 33679735
Immunobiology. 2012 Aug;217(8):768-77
pubmed: 22672991
PLoS One. 2014 Apr 21;9(4):e95977
pubmed: 24752321
OMICS. 2012 May;16(5):284-7
pubmed: 22455463
Circ Arrhythm Electrophysiol. 2017 Jan;10(1):
pubmed: 28087563
Genome Biol. 2014;15(12):550
pubmed: 25516281
Immunity. 1998 Jun;8(6):693-701
pubmed: 9655483
Scand J Immunol. 2005 Sep;62(3):297-308
pubmed: 16179017
J Infect Dis. 2017 Feb 1;215(3):387-395
pubmed: 28003350
PLoS One. 2013;8(2):e57181
pubmed: 23451183
Lancet. 2010 Apr 17;375(9723):1388-402
pubmed: 20399979
J Innate Immun. 2013;5(4):389-400
pubmed: 23571507
J Biol Chem. 1998 Oct 9;273(41):26923-30
pubmed: 9756940
Clin Infect Dis. 2021 May 4;72(9):e303-e310
pubmed: 32766826
PLoS One. 2012;7(5):e35966
pubmed: 22574131
PLoS Negl Trop Dis. 2011 Aug;5(8):e1294
pubmed: 21886854
Infect Immun. 1993 Dec;61(12):5129-33
pubmed: 8225589
Arq Bras Cardiol. 2023 Jun 26;120(6):e20230269
pubmed: 37377258
Pathogens. 2022 Nov 23;11(12):
pubmed: 36558736
Exp Mol Med. 2019 Dec 19;51(12):1-13
pubmed: 31857574
Int Immunol. 1996 Jan;8(1):13-22
pubmed: 8671585
Immunology. 2010 Jan;129(1):28-40
pubmed: 19824921
PLoS Negl Trop Dis. 2018 Jun 13;12(6):e0006567
pubmed: 29897909
Nat Immunol. 2009 Oct;10(10):1073-80
pubmed: 19701189
Cell Rep. 2014 Nov 6;9(3):1075-88
pubmed: 25437561
Immunity. 1999 Dec;11(6):743-52
pubmed: 10626896
PLoS One. 2018 Nov 29;13(11):e0208133
pubmed: 30496249
Am J Med. 2020 Nov;133(11):1262-1265
pubmed: 32592664
Cell Rep. 2019 Feb 5;26(6):1627-1640.e7
pubmed: 30726743
Circ Res. 2016 Jun 24;119(1):159-76
pubmed: 27340274
Open Forum Infect Dis. 2021 Mar 02;8(4):ofab096
pubmed: 33884277
Am J Clin Pathol. 2016 Aug;146(2):191-8
pubmed: 27425387
Circulation. 2018 Sep 18;138(12):e169-e209
pubmed: 30354432
J Am Heart Assoc. 2014 Feb 07;3(1):e000632
pubmed: 24510116
N Engl J Med. 2015 Oct;373(14):1295-306
pubmed: 26323937
Clin Infect Dis. 2017 Jul 15;65(2):268-275
pubmed: 28369287
Infect Immun. 1994 May;62(5):1820-9
pubmed: 8168945
Sci Data. 2022 Jun 24;9(1):360
pubmed: 35750679
Cell Immunol. 2020 Feb;348:103974
pubmed: 31879029
Expert Opin Pharmacother. 2019 Oct;20(15):1797-1807
pubmed: 31456439
PLoS Pathog. 2021 Apr 7;17(4):e1009502
pubmed: 33826673
Genome Biol. 2017 Nov 15;18(1):220
pubmed: 29141660
Cardiology. 1992;80(5-6):424-37
pubmed: 1451131
PLoS Negl Trop Dis. 2021 Feb 4;15(2):e0009059
pubmed: 33539379
Transpl Immunol. 2008 Jan;18(3):250-4
pubmed: 18047933
Infect Genet Evol. 2021 Nov;95:105079
pubmed: 34509648
Scand J Immunol. 2007 Aug-Sep;66(2-3):362-71
pubmed: 17635814
Front Immunol. 2018 Aug 24;9:1929
pubmed: 30197647

Auteurs

Carolina Duque (C)

Department of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

Jaime So (J)

Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Yagahira E Castro-Sesquen (YE)

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Kelly DeToy (K)

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Sneider A Gutierrez Guarnizo (SA)

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Fatemeh Jahanbakhsh (F)

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Edith Malaga Machaca (EM)

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Monica Miranda-Schaeubinger (M)

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Indira Chakravarti (I)

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Virginia Cooper (V)

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Mary E Schmidt (ME)

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Luigi Adamo (L)

Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Rachel Marcus (R)

MedStar Washington Hospital Center, Washington, D.C., USA.

Kawsar R Talaat (KR)

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Robert H Gilman (RH)

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Monica R Mugnier (MR)

Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Classifications MeSH