Controlling pericellular oxygen tension in cell culture reveals distinct breast cancer responses to low oxygen tensions.

anoxia breast cancer cancer metabolism cell culture hypoxia hypoxia-inducible factors oxygen physioxia

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
03 Oct 2023
Historique:
pubmed: 24 10 2023
medline: 24 10 2023
entrez: 24 10 2023
Statut: epublish

Résumé

Oxygen (O

Identifiants

pubmed: 37873449
doi: 10.1101/2023.10.02.560369
pmc: PMC10592900
pii:
doi:

Types de publication

Preprint

Langues

eng

Déclaration de conflit d'intérêts

Competing Interests The authors declare no conflicts of interest.

Auteurs

Zachary J Rogers (ZJ)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.

Thibault Colombani (T)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.

Saad Khan (S)

Department of Bioengineering, Northeastern University, Boston, MA 02115, USA.

Khushbu Bhatt (K)

Department of Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.

Alexandra Nukovic (A)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.

Guanyu Zhou (G)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.

Benjamin M Woolston (BM)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.

Cormac T Taylor (CT)

Conway Institute of Biomolecular and Biomedical Research and School of Medicine, University College Dublin, Belfield, Dublin, Ireland.

Daniele M Gilkes (DM)

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21321, USA.
Cellular and Molecular Medicine Program, The Johns Hopkins University School of Medicine, Baltimore, MD 21321, USA.
Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.
Johns Hopkins Institute for NanoBioTechnology, The Johns Hopkins University, Baltimore, MD 21218, USA.

Nikolai Slavov (N)

Departments of Bioengineering, Biology, Chemistry and Chemical Biology, Single Cell Center and Barnett Institute, Northeastern University, Boston, MA 02115 USA.
Parallel Squared Technology Institute, Watertown, MA 02135 USA.

Sidi A Bencherif (SA)

Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.
Department of Bioengineering, Northeastern University, Boston, MA 02115, USA.
Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.
Biomechanics and Bioengineering (BMBI), UTC CNRS UMR 7338, University of Technology of Compiègne, Sorbonne University, 60203 Compiègne, France.

Classifications MeSH