Can Hydrogen Water Enhance Oxygen Saturation in Patients with Chronic Lung Disease? A Non-Randomized, Observational Pilot Study.

COPD COVD-19 antioxidant hydrogen-rich water hypoxia inflammation oxidative stress

Journal

Diseases (Basel, Switzerland)
ISSN: 2079-9721
Titre abrégé: Diseases
Pays: Switzerland
ID NLM: 101636232

Informations de publication

Date de publication:
26 Sep 2023
Historique:
received: 21 08 2023
revised: 20 09 2023
accepted: 22 09 2023
medline: 24 10 2023
pubmed: 24 10 2023
entrez: 24 10 2023
Statut: epublish

Résumé

Recently, chronic lung diseases have been found to be associated with marked inflammation and oxidative stress, which leads to fibrosis in the lungs and chronic respiratory failure. This study aims to determine if hydrogen-rich water (HRW) can enhance oxygen saturation among patients with chronic lung diseases. Ten patients with chronic lung diseases due to COPD ( HRW administration was associated with a significant increase in oxygen saturation (SpO Treatment with HRW in patients with hypoxia from chronic lung diseases may decrease oxidative stress and improve oxygen saturation in some patients. HRW therapy may also provide increased exercise tolerance in patients with chronic hypoxia, but further research is needed.

Sections du résumé

BACKGROUND BACKGROUND
Recently, chronic lung diseases have been found to be associated with marked inflammation and oxidative stress, which leads to fibrosis in the lungs and chronic respiratory failure. This study aims to determine if hydrogen-rich water (HRW) can enhance oxygen saturation among patients with chronic lung diseases.
METHODS METHODS
Ten patients with chronic lung diseases due to COPD (
RESULTS RESULTS
HRW administration was associated with a significant increase in oxygen saturation (SpO
CONCLUSION CONCLUSIONS
Treatment with HRW in patients with hypoxia from chronic lung diseases may decrease oxidative stress and improve oxygen saturation in some patients. HRW therapy may also provide increased exercise tolerance in patients with chronic hypoxia, but further research is needed.

Identifiants

pubmed: 37873771
pii: diseases11040127
doi: 10.3390/diseases11040127
pmc: PMC10594520
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Int J Chron Obstruct Pulmon Dis. 2015 Feb 02;10:261-76
pubmed: 25673984
Thorax. 2003 Apr;58(4):289-93
pubmed: 12668787
Surgery. 2015 Aug;158(2):399-407
pubmed: 25983276
Oncotarget. 2017 Sep 21;8(60):102653-102673
pubmed: 29254278
Respiration. 2019;97(1):42-51
pubmed: 30227423
Am J Respir Crit Care Med. 2017 Apr 1;195(7):871-880
pubmed: 27736154
Diabetes Metab Syndr Obes. 2020 Mar 24;13:889-896
pubmed: 32273740
Respir Res. 2021 May 13;22(1):149
pubmed: 33985501
Int J Chron Obstruct Pulmon Dis. 2011;6:413-21
pubmed: 21857781
Free Radic Res. 2010 Sep;44(9):971-82
pubmed: 20815764
Biochem Biophys Res Commun. 2017 Oct 7;492(1):74-81
pubmed: 28807355
Clin Case Rep. 2021 Nov 06;9(11):e05039
pubmed: 34765212
JAMA. 2017 Jun 6;317(21):2177-2186
pubmed: 28528348
J Integr Neurosci. 2021 Sep 30;20(3):667-676
pubmed: 34645100
QJM. 2020 Dec 1;113(12):870-875
pubmed: 32407476
Life (Basel). 2023 Feb 02;13(2):
pubmed: 36836774
QJM. 2021 Feb 18;114(1):74-75
pubmed: 33151329
Front Pharmacol. 2020 Oct 15;11:543718
pubmed: 33178011
Med Gas Res. 2013 Aug 04;3(1):18
pubmed: 23916029
EBioMedicine. 2022 May;79:103994
pubmed: 35417845
Pharmacol Ther. 2014 Oct;144(1):1-11
pubmed: 24769081
Nat Med. 2007 Jun;13(6):688-94
pubmed: 17486089

Auteurs

Ram B Singh (RB)

Department of Medicine, Halberg Hospital and Research Institute, Moradabad 244001, India.

Alex Tarnava (A)

Natural Wellness Now Health Products Inc., Maple Ridge, BC V4R 2S6, Canada.

Ghizal Fatima (G)

Department of Biotechnology, Era's Lucknow Medical College and Hospital, Lucknow 226003, India.

Jan Fedacko (J)

Centre of Clinical and Preclinical Research-MEDIPARK, Pavol Jozef Safarik University, 040 11 Kosice, Slovakia.

Viliam Mojto (V)

Third Department of Internal Medicine, Faculty of Medicine, Comenius University, 813 72 Bratislava, Slovakia.

Tyler W LeBaron (TW)

Molecular Hydrogen Institute, Cedar City, UT 84720, USA.
Department of Kinesiology and Outdoor Recreation, Southern Utah University, Cedar, UT 84720, USA.

Classifications MeSH