Ovotesticular disorder of sex development in a 46 XY adolescent: a rare case report with review of the literature.
Adolescent
Disorders of Sex Development (DSD)
Histology
Karyotype
Ovotestis
Journal
BMC women's health
ISSN: 1472-6874
Titre abrégé: BMC Womens Health
Pays: England
ID NLM: 101088690
Informations de publication
Date de publication:
24 10 2023
24 10 2023
Historique:
received:
29
03
2023
accepted:
09
10
2023
medline:
30
10
2023
pubmed:
25
10
2023
entrez:
24
10
2023
Statut:
epublish
Résumé
Ovotestis is a rare cause of sexual ambiguity characterized by the presence in a patient of both testicular and ovarian tissue, leading to the development of both male and female structures. We report a case of ovotestis diagnosed in an adolescent, with a review of the literature. A 15-year-old patient presented with a right scrotal swelling associated with gynecomastia. Histology showed a juxtaposition of ovarian stroma with ovarian follicle and seminiferous tubules. Karyotype revealed a male subject (XY). We have therefore retained the diagnosis of ovotesticular disorders of sex development. Ovotestis is a rare finding, heterogeneous in its genetic etiology and clinical presentation. While many patients are diagnosed during infancy or childhood, we presented a case diagnosed in a 15-year-old adolescent.
Identifiants
pubmed: 37875919
doi: 10.1186/s12905-023-02698-1
pii: 10.1186/s12905-023-02698-1
pmc: PMC10594775
doi:
Types de publication
Review
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
549Informations de copyright
© 2023. BioMed Central Ltd., part of Springer Nature.
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