A Strategy for Rescuing a Child From Clonazepam Poisoning: A Case Study.
Journal
Therapeutic drug monitoring
ISSN: 1536-3694
Titre abrégé: Ther Drug Monit
Pays: United States
ID NLM: 7909660
Informations de publication
Date de publication:
01 Apr 2024
01 Apr 2024
Historique:
received:
23
05
2023
accepted:
15
08
2023
medline:
18
3
2024
pubmed:
25
10
2023
entrez:
25
10
2023
Statut:
ppublish
Résumé
This report describes the successful rescue of a 12-year-old girl who ingested large quantities of clonazepam tablets. The patient was promptly treated with flumazenil and hemoperfusion to alleviate the symptoms of central depression. Therapeutic drug monitoring was used to evaluate detoxification efficacy. The authors analyzed the rescue protocol for clonazepam poisoning based on the pathophysiology, clinical manifestations, and pharmacokinetics of clonazepam overdose. The patient responded well to the treatment and was discharged from the hospital without adverse events. This case study demonstrated the effectiveness and safety of combining flumazenil with hemoperfusion as a treatment for clonazepam poisoning. This study aimed to provide insights into more effective methods for treating clonazepam overdose and contribute to the ongoing issue of managing this condition.
Sections du résumé
BACKGROUND
BACKGROUND
This report describes the successful rescue of a 12-year-old girl who ingested large quantities of clonazepam tablets.
METHODS
METHODS
The patient was promptly treated with flumazenil and hemoperfusion to alleviate the symptoms of central depression. Therapeutic drug monitoring was used to evaluate detoxification efficacy. The authors analyzed the rescue protocol for clonazepam poisoning based on the pathophysiology, clinical manifestations, and pharmacokinetics of clonazepam overdose.
RESULTS
RESULTS
The patient responded well to the treatment and was discharged from the hospital without adverse events.
CONCLUSIONS
CONCLUSIONS
This case study demonstrated the effectiveness and safety of combining flumazenil with hemoperfusion as a treatment for clonazepam poisoning. This study aimed to provide insights into more effective methods for treating clonazepam overdose and contribute to the ongoing issue of managing this condition.
Identifiants
pubmed: 37876261
doi: 10.1097/FTD.0000000000001148
pii: 00007691-990000000-00156
doi:
Substances chimiques
Clonazepam
5PE9FDE8GB
Flumazenil
40P7XK9392
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
138-140Informations de copyright
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
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